The membrane emulsification process—a review

2004 ◽  
Vol 79 (3) ◽  
pp. 209-218 ◽  
Author(s):  
C Charcosset ◽  
I Limayem ◽  
H Fessi
Keyword(s):  
Membrane Emulsification ◽  
Emulsification Process

scholarly journals Microencapsulation of Enteric Bacteriophages in a pH-Responsive Solid Oral Dosage Formulation Using a Scalable Membrane Emulsification Process

Pharmaceutics ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 475 ◽  
Author(s):  
Vinner ◽  
Richards ◽  
Leppanen ◽  
Sagona ◽  
Malik
Keyword(s):  
Epithelial Cells ◽  
Prolonged Exposure ◽  
Oral Dosage ◽  
Bacterial Cells ◽  
Ph Responsive ◽  
Ion Milling ◽  
Membrane Emulsification ◽  
E Coli ◽  
Emulsification Process

A scalable low-shear membrane emulsification process was used to produce microencapsulated Escherichia coli-phages in a solid oral dosage form. Uniform pH-responsive composite microparticles (mean size ~100 µm) composed of Eudragit® S100 and alginate were produced. The internal microstructure of the gelled microcapsules was studied using ion-milling and imaging, which showed that the microparticles had a solid internal core. The microencapsulation process significantly protected phages upon prolonged exposure to a simulated gastric acidic environment. Encapsulated phages that had been pre-exposed to simulated gastric acid were added to actively growing bacterial cells using in vitro cell cultures and were found to be effective in killing E. coli. Encapsulated phages were also shown to be effective in killing actively growing E. coli in the presence of human epithelial cells. Confocal microscopy images showed that the morphology of encapsulated phage-treated epithelial cells was considerably better than controls without phage treatment. The encapsulated phages were stable during refrigerated storage over a four-week period. The process of membrane emulsification is highly scalable and is a promising route to produce industrial quantities of pH-responsive oral solid dosage forms suitable for delivering high titres of viable phages to the gastrointestinal tract.

scholarly journals Linking Findings in Microfluidics to Membrane Emulsification Process Design: The Importance of Wettability and Component Interactions with Interfaces

Membranes ◽  
2016 ◽  
Vol 6 (2) ◽  
pp. 26 ◽  
Author(s):  
Karin Schroën ◽  
Montse Ferrando ◽  
Silvia de Lamo-Castellví ◽  
Sami Sahin ◽  
Carme Güell
Keyword(s):  
Process Design ◽  
Membrane Emulsification ◽  
Emulsification Process

scholarly journals Vinaigrette Production by Membrane Emulsification: Process Optimization and Product Development

2015 ◽  
Vol 59 (3) ◽  
pp. 206-208
Author(s):  
Krisztina Albert ◽  
András Koris ◽  
Shabbir Ahammed ◽  
Igor Gáspár ◽  
Gyula Vatai
Keyword(s):  
Product Development ◽  
Process Optimization ◽  
Membrane Emulsification ◽  
Emulsification Process

scholarly journals Membrane Emulsification Process as a Method for Obtaining Molecularly Imprinted Polymers

Polymers ◽  
2021 ◽  
Vol 13 (16) ◽  
pp. 2830
Author(s):  
Joanna Wolska ◽  
Nasim Jalilnejad Falizi
Keyword(s):  
Molecularly Imprinted Polymer ◽  
Molecularly Imprinted Polymers ◽  
Binding Capacity ◽  
Aqueous Media ◽  
Sorption Process ◽  
Imprinted Polymer ◽  
Membrane Emulsification ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Emulsification Process

The membrane emulsification process (ME) using a metallic membrane was the first stage for preparing a spherical and monodisperse thermoresponsive molecularly imprinted polymer (TSMIP). In the second step of the preparation, after the ME process, the emulsion of monomers was then polymerized. Additionally, the synthesized TSMIP was fabricated using as a functional monomer N-isopropylacrylamide, which is thermosensitive. This special type of polymer was obtained for the recognition and determination of trace bisphenol A (BPA) in aqueous media. Two types of molecularly imprinted polymers (MIPs) were synthesized using amounts of BPA of 5 wt.% (MIP-2) and 7 wt.% (MIP-1) in the reaction mixtures. Additionally, a non-imprinted polymer (NIP) was also synthesized. Polymer MIP-2 showed thermocontrolled recognition for imprinted molecules and a higher binding capacity than its corresponding non-imprinted polymer and higher than other molecularly imprinted polymer (MIP-1). The best condition for the sorption process was at a temperature of 35 °C, that is, at a temperature close to the phase transition value for poly(N-isopropylacrylamide). Under these conditions, the highest levels of BPA removal from water were achieved and the highest adsorption capacity of MIP-2 was about 0.5 mmol g−1 (about 114.1 mg g−1) and was approximately 20% higher than for MIP-1 and NIP. It was also observed that during the kinetic studies, under these temperature conditions, MIP-2 sorbed BPA faster and with greater efficiency than its non-imprinted analogue.

Optimizing stirred cell membrane emulsification process for making a food-grade multiple emulsion

2017 ◽  
Vol 72 (3) ◽  
pp. 533-542 ◽  
Author(s):  
Branislava G. Nikolovski ◽  
Jelena D. Bajac ◽  
Ferenc L. Martinovic ◽  
Nenad Bogunović
Keyword(s):  
Cell Membrane ◽  
Multiple Emulsion ◽  
Membrane Emulsification ◽  
Food Grade ◽  
Stirred Cell ◽  
Emulsification Process
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