Improvement of natamycin production by controlling the morphology of Streptomyces gilvosporeus Z8 with microparticle talc in seed preculture

2021 ◽  
Author(s):  
Chaoping Yue ◽  
Haitao Xu ◽  
Yingying Yu ◽  
Xin Yu ◽  
Min Yu ◽  
...  
Keyword(s):  
Natamycin Production

scholarly journals WblAch, a Pivotal Activator of Natamycin Biosynthesis and Morphological Differentiation in Streptomyces chattanoogensis L10, Is Positively Regulated by AdpAch

2014 ◽  
Vol 80 (22) ◽  
pp. 6879-6887 ◽  
Author(s):  
Pin Yu ◽  
Shui-Ping Liu ◽  
Qing-Ting Bu ◽  
Zhen-Xing Zhou ◽  
Zhen-Hong Zhu ◽  
...  
Keyword(s):  
Morphological Differentiation ◽  
Binding Activity ◽  
Transcriptional Analysis ◽  
Antibiotic Biosynthesis ◽  
Content Type ◽  
Real Time Quantitative Pcr ◽  
Dna Binding Activity ◽  
In The Wild ◽  
Natamycin Production ◽  
Streptomyces Chattanoogensis

ABSTRACTDetailed mechanisms ofWhiB-like (Wbl) proteins involved in antibiotic biosynthesis and morphological differentiation are poorly understood. Here, we characterize the role of WblAch, aStreptomyces chattanoogensisL10 protein belonging to this superfamily. Based on DNA microarray data and verified by real-time quantitative PCR (qRT-PCR), the expression ofwblAchwas shown to be positively regulated by AdpAch. Gel retardation assays and DNase I footprinting experiments showed that AdpAchhas specific DNA-binding activity for the promoter region ofwblAch. Gene disruption and genetic complementation revealed that WblAchacts in a positive manner to regulate natamycin production. WhenwblAchwas overexpressed in the wild-type strain, the natamycin yield was increased by ∼30%. This provides a strategy to generate improved strains for natamycin production. Moreover, transcriptional analysis showed that the expression levels ofwhigenes (includingwhiA,whiB,whiH, andwhiI) were severely depressed in the ΔwblAchmutant, suggesting that WblAchplays a part in morphological differentiation by influencing the expression of thewhigenes.

Identification of a novel Streptomyces chattanoogensis L10 and enhancing its natamycin production by overexpressing positive regulator ScnRII

2009 ◽  
Vol 47 (4) ◽  
pp. 506-513 ◽  
Author(s):  
Yi-Ling Du ◽  
Shi-Fei Chen ◽  
Liang-Ying Cheng ◽  
Xue-Ling Shen ◽  
Yuan Tian ◽  
...  
Keyword(s):  
Positive Regulator ◽  
Natamycin Production ◽  
Streptomyces Chattanoogensis

Optimization of the cultivation medium for natamycin production byStreptomyces natalensis

2000 ◽  
Vol 40 (3) ◽  
pp. 157-166 ◽  
Author(s):  
Mohamed A. Farid ◽  
Hesham A. El-Enshasy ◽  
Ahmed I. El-Diwany ◽  
El-Sayed A. El-Sayed
Keyword(s):  
Cultivation Medium ◽  
Natamycin Production

Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy

2016 ◽  
Vol 38 ◽  
pp. 418-426 ◽  
Author(s):  
Yemin Wang ◽  
Zhengsheng Tao ◽  
Hualiang Zheng ◽  
Fei Zhang ◽  
Qingshan Long ◽  
...  
Keyword(s):  
Natamycin Production

Sigma factor WhiGch positively regulates natamycin production in Streptomyces chattanoogensis L10

2015 ◽  
Vol 99 (6) ◽  
pp. 2715-2726 ◽  
Author(s):  
Shui-Ping Liu ◽  
Pin Yu ◽  
Peng-Hui Yuan ◽  
Zhen-Xing Zhou ◽  
Qing-Ting Bu ◽  
...  
Keyword(s):  
Sigma Factor ◽  
Natamycin Production ◽  
Streptomyces Chattanoogensis

Genome Shuffling ofStreptomyces gilvosporeusfor Improving Natamycin Production

2012 ◽  
Vol 60 (23) ◽  
pp. 6026-6036 ◽  
Author(s):  
Jian-Mei Luo ◽  
Jian-Shu Li ◽  
Dan Liu ◽  
Feng Liu ◽  
Yan-Ting Wang ◽  
...  
Keyword(s):  
Genome Shuffling ◽  
Natamycin Production

scholarly journals Comparative Genomic and Regulatory Analyses of Natamycin Production of Streptomyces lydicus A02

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Huiling Wu ◽  
Weicheng Liu ◽  
Lingling Shi ◽  
Kaiwei Si ◽  
Ting Liu ◽  
...  
Keyword(s):  
Comparative Genomic ◽  
Streptomyces Lydicus ◽  
Natamycin Production

Continuous natamycin production by using immobilized Streptomyces gilvosporeus Z8 via repeated batch culture

2019 ◽  
Vol 95 (1) ◽  
pp. 73-77 ◽  
Author(s):  
Xin Zeng ◽  
Huawei Zeng ◽  
Yi Meng ◽  
Dayong Xu ◽  
Biao Zhang ◽  
...  
Keyword(s):  
Batch Culture ◽  
Repeated Batch Culture ◽  
Repeated Batch ◽  
Natamycin Production

Improvement in natamycin production by Streptomyces natalensis with the addition of short-chain carboxylic acids

2013 ◽  
Vol 48 (12) ◽  
pp. 1831-1838 ◽  
Author(s):  
Elsayed Ahmed Elsayed ◽  
Mohamed Abdel Fattah Farid ◽  
Hesham Ali El Enshasy
Keyword(s):  
Carboxylic Acids ◽  
Short Chain ◽  
Streptomyces Natalensis ◽  
Natamycin Production
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