Synthesis of novel polyesters for potential applications in skin tissue engineering

2015 ◽  
Vol 91 (3) ◽  
pp. 733-741 ◽  
Author(s):  
Akanksha Kanitkar ◽  
Mollie Smoak ◽  
Cong Chen ◽  
Giovanna Aita ◽  
Thomas Scherr ◽  
...  
RSC Advances ◽  
2016 ◽  
Vol 6 (77) ◽  
pp. 73636-73644 ◽  
Author(s):  
Kui Yu ◽  
Xiangxiang Zhou ◽  
Tonghe Zhu ◽  
Tong Wu ◽  
Juan Wang ◽  
...  

In this study, PEUU was blended with gelatin for electrospun nanofiber and nanoyarn. PEUU/gelatin with a mass ratio of 75 : 25 showed better comprehensive property than nanofiber thus paving way for the further research in tissue engineering field.


Author(s):  
Marketa Bacakova ◽  
Jana Musilkova ◽  
Tomas Riedel ◽  
Denisa Stranska ◽  
Eduard Brynda ◽  
...  

2018 ◽  
Author(s):  
Antonios Keirouz ◽  
Giuseppino Fortunato ◽  
Anthony Callanan ◽  
Norbert Radacsi

Scaffolds and implants used for tissue engineering need to be adapted for their mechanical properties with respect to their environment within the human body. Therefore, a novel composite for skin tissue engineering is presented by use of blends of Poly(vinylpyrrolidone) (PVP) and Poly(glycerol sebacate) (PGS) were fabricated via the needleless electrospinning technique. The formed PGS/PVP blends were morphologically, thermochemically and mechanically characterized. The morphology of the developed fibers related to the concentration of PGS, with high concentrations of PGS merging the fibers together plasticizing the scaffold. The tensile modulus appeared to be affected by the concentration of PGS within the blends, with an apparent decrease in the elastic modulus of the electrospun mats and an exponential increase of the elongation at break. Ultraviolet (UV) crosslinking of PGS/PVP significantly decreased and stabilized the wettability of the formed fiber mats, as indicated by contact angle measurements. In vitro examination showed good viability and proliferation of human dermal fibroblasts over the period of a week. The present findings provide important insights for tuning the elastic properties of electrospun material by incorporating this unique elastomer, as a promising future candidate for skin substitute constructs.


3 Biotech ◽  
2021 ◽  
Vol 11 (4) ◽  
Author(s):  
Satyavrat Tripathi ◽  
Bhisham Narayan Singh ◽  
Divakar Singh ◽  
Gaurav kumar ◽  
Pradeep Srivastava

Author(s):  
Chao Wei ◽  
Yihua Feng ◽  
Dezhao Che ◽  
Jiahui Zhang ◽  
Xuan Zhou ◽  
...  

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