Optimization of process parameters and dissolution kinetics of nickel and cobalt from lateritic chromite overburden using organic acids

2014 ◽  
Vol 89 (10) ◽  
pp. 1491-1500 ◽  
Author(s):  
Supratim Biswas ◽  
Suparna Chakraborty ◽  
Mahua Ghosh Chaudhuri ◽  
Pataki C Banerjee ◽  
Siddhartha Mukherjee ◽  
...  
Keyword(s):  
Organic Acids ◽  
Process Parameters ◽  
Dissolution Kinetics ◽  
Optimization Of Process Parameters ◽  
Chromite Overburden ◽  
Kinetics Of

scholarly journals Study on Optimization of Wet Milling Process for the Development of Albendazole Containing Nanosuspension with Improved Dissolution

2020 ◽  
Vol 64 (4) ◽  
pp. 401-420
Author(s):  
Viktor Fülöp ◽  
Géza Jakab ◽  
Bence Tóth ◽  
Emese Balogh ◽  
István Antal
Keyword(s):  
Process Parameters ◽  
Dissolution Kinetics ◽  
Polymorphic Transition ◽  
Milling Process ◽  
Process Time ◽  
Wet Milling ◽  
Influence Of Process Parameters ◽  
Freundlich Equation ◽  
Milling Medium ◽  
Kinetics Of

The main objective of this work was to show the potential of the optimization of top-down wet planetary bead milling process parameters (milling speed, process time and size of the milling medium) by Design Of Experiments (DOE) approach for the development of albendazole (ABZ) containing nanosuspension with improved dissolution. In addition, the influence of process parameters (capacity of milling container, applied volume of milling beads, size of the milling medium, milling speed, milling time) on ABZ polymorphic transition has also been investigated. The optimized, milled formula yielded ~ 145.39 times reduction in mean particle size (182.200 ± 1.3130 nm) compared to unmilled dispersion, which demonstrated 13.50 times gain in mean dissolution rate value compared to the unmilled dispersion in medium at pH = 1.2. No lag time values were observed in the dissolution kinetics of the nanosuspension in comparison with the unmilled samples. Moreover, maximal mean solubility value was also improved by 1.45 times compared to the unmilled suspension, in medium at pH = 6.8, supporting the significance of the Ostwald-Freundlich equation. Diffraction pattern comparisons have indicated a polymorphic transition of albendazole to Form II, which was more pronounced in smaller container at high milling speed values and prolonged operations.

Dissolution kinetics of a lunar glass simulant at 25 °C: The effect of pH and organic acids

1996 ◽  
Vol 60 (1) ◽  
pp. 157-170 ◽  
Author(s):  
M.J. Eick ◽  
P.R. Grossl ◽  
D.C. Golden ◽  
D.L. Sparks ◽  
D.W. Ming
Keyword(s):  
Organic Acids ◽  
Dissolution Kinetics ◽  
Effect Of Ph ◽  
Kinetics Of

Dissolution kinetics of chromite overburden by using mineral acids

2007 ◽  
Vol 24 (6) ◽  
pp. 932-935 ◽  
Author(s):  
P. K. Swain ◽  
Gautam Roy Chaudhury ◽  
L. B. Sukla
Keyword(s):  
Dissolution Kinetics ◽  
Mineral Acids ◽  
Chromite Overburden ◽  
Kinetics Of

Optimization of Process Parameters for Production of Pectinase using Bacillus Subtilis MF447840.1

2019 ◽  
Vol 13 (1) ◽  
pp. 69-73 ◽  
Author(s):  
Ram Balak Mahto ◽  
Mukesh Yadav ◽  
Soumya Sasmal ◽  
Biswnath Bhunia
Keyword(s):  
Bacillus Subtilis ◽  
Process Parameters ◽  
Volume Ratio ◽  
Optimum Process ◽  
Agitation Rate ◽  
Fermentation Condition ◽  
Optimization Of Process Parameters ◽  
Food And Beverage ◽  
Pectinase Production ◽  
Sterile Product

Background: Pectinase enzyme has immense industrial prospects in the food and beverage industries. </P><P> Objective: In our investigation, we find out the optimum process parameters suitable for better pectinase generation by Bacillus subtilis MF447840.1 using submerged fermentation. </P><P> Method: 2% (OD600 nm = 0.2) of pure Bacillus subtilis MF447840.1 bacterial culture was inoculated in sterile product production media. The production media components used for this study were 1 g/l of pectin, 2 g/l of (NH4)2SO4, 1 g/l of NaCl, 0.25 g/l of K2HPO4, 0.25 g/l of KH2PO4 and 1 g/l of MgSO4 for pectinase generation. We reviewed all recent patents on pectinase production and utilization. The various process parameters were observed by changing one variable time method. </P><P> Results: The optimum fermentation condition of different parameters was noticed to be 5% inoculums, 25% volume ratio, temperature (37°C), pH (7.4) and agitation rate (120 rpm) following 4 days incubation. </P><P> Conclusion: Maximum pectinase generation was noticed as 345 ± 12.35 U following 4 days incubation.

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