Direct extraction of phenylacetic acid from immobilised enzymatic hydrolysis of penicillin G with cloud point extraction

2006 ◽  
Vol 81 (4) ◽  
pp. 560-565 ◽  
Author(s):  
Zhilong Wang ◽  
Yajing Guo ◽  
Da Bao ◽  
Hanshi Qi
Keyword(s):  
Enzymatic Hydrolysis ◽  
Cloud Point ◽  
Phenylacetic Acid ◽  
Cloud Point Extraction ◽  
Penicillin G ◽  
Direct Extraction ◽  
Hydrolysis Of

Enzymatic hydrolysis of penicillin G in ionic liquids

2008 ◽  
Vol 136 ◽  
pp. S391
Author(s):  
Mai Ngoc Lan ◽  
Sung Ho Ha ◽  
Yoon-Mo Koo
Keyword(s):  
Ionic Liquids ◽  
Enzymatic Hydrolysis ◽  
Penicillin G ◽  
Hydrolysis Of

Improving the Industrial Production of 6-APA: Enzymatic Hydrolysis of Penicillin G in the Presence of Organic Solvents

2003 ◽  
Vol 19 (6) ◽  
pp. 1639-1642 ◽  
Author(s):  
O. Abian ◽  
C. Mateo ◽  
G. Fernandez-Lorente ◽  
J.M. Guisan ◽  
R. Fernandez-Lafuente
Keyword(s):  
Enzymatic Hydrolysis ◽  
Organic Solvents ◽  
Industrial Production ◽  
Penicillin G ◽  
Hydrolysis Of

scholarly journals Preparation of Sterically Demanding 2,2-Disubstituted-2-Hydroxy Acids by Enzymatic Hydrolysis

Catalysts ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 113 ◽  
Author(s):  
Andrea Pinto ◽  
Immacolata Serra ◽  
Diego Romano ◽  
Martina Contente ◽  
Francesco Molinari ◽  
...  
Keyword(s):  
Enzymatic Hydrolysis ◽  
Phenylacetic Acid ◽  
General Structure ◽  
Hydroxy Acids ◽  
Pig Liver Esterase ◽  
Liver Esterase ◽  
Sterically Demanding ◽  
Optically Pure ◽  
Hydrolysis Of ◽  
Derivatives Of

Preparation of optically-pure derivatives of 2-hydroxy-2-(3-hydroxyphenyl)-2-phenylacetic acid of general structure 2 was accomplished by enzymatic hydrolysis of the correspondent esters. A screening with commercial hydrolases using the methyl ester of 2-hydroxy-2-(3-hydroxyphenyl)-2-phenylacetic acid (1a) showed that crude pig liver esterase (PLE) was the only preparation with catalytic activity. Low enantioselectivity was observed with substrates 1a–d, whereas PLE-catalysed hydrolysis of 1e proceeded with good enantioselectivity (E = 28), after optimization. Enhancement of the enantioselectivity was obtained by chemical re-esterification of enantiomerically enriched 2e, followed by sequential enzymatic hydrolysis with PLE. The preparation of optically-pure (S)-2e was validated on multi-milligram scale.

Extraction and enzymatic hydrolysis of Penicillin G in emulsion liquid membranes

1996 ◽  
Vol 208 (1) ◽  
pp. 133-144 ◽  
Author(s):  
I. Miesiąc ◽  
K. Schügerl ◽  
A. Hasler ◽  
J. Szymanowski
Keyword(s):  
Enzymatic Hydrolysis ◽  
Penicillin G ◽  
Liquid Membranes ◽  
Emulsion Liquid Membranes ◽  
Hydrolysis Of

Equilibrium modeling of extractive enzymatic hydrolysis of penicillin G with concomitant 6-aminopenicillanic acid crystallization

2002 ◽  
Vol 78 (4) ◽  
pp. 395-402 ◽  
Author(s):  
M. B. Diender ◽  
A. J. J. Straathof ◽  
T. van der Does ◽  
C. Ras ◽  
J. J. Heijnen
Keyword(s):  
Enzymatic Hydrolysis ◽  
Penicillin G ◽  
Equilibrium Modeling ◽  
Hydrolysis Of
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