Variant Inosine Triphosphatase Phenotypes Are Associated With Increased Ribavirin Triphosphate Levels

2016 ◽  
Vol 57 (1) ◽  
pp. 118-124 ◽  
Author(s):  
Leah C. Jimmerson ◽  
Thomas J. Urban ◽  
Aimee Truesdale ◽  
Fafa Baouchi-Mokrane ◽  
Shyam Kottilil ◽  
...  
Keyword(s):  
Inosine Triphosphatase

Assignment of inosine triphosphatasegene to gorilla chromosome 13 and to human chromosome 20 in primate-rodent somatic cell hybrids

1976 ◽  
Vol 16 (1-5) ◽  
pp. 420-421 ◽  
Author(s):  
Meera Khan ◽  
P.L. Pearson ◽  
L.L.L. Wijnen ◽  
B.A. Doppert ◽  
A. Westerveld ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Somatic Cell ◽  
Somatic Cell Hybrids ◽  
Chromosome 13 ◽  
Cell Hybrids ◽  
Chromosome 20 ◽  
I Gene ◽  
Inosine Triphosphatase

Pharmacogenetic significance of inosine triphosphatase

2007 ◽  
Vol 8 (9) ◽  
pp. 1221-1228 ◽  
Author(s):  
Jörgen Bierau ◽  
Martijn Lindhout ◽  
Jaap A Bakker
Keyword(s):  
Inosine Triphosphatase

Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy

2013 ◽  
Vol 20 (12) ◽  
pp. 858-866 ◽  
Author(s):  
P. J. Clark ◽  
A. Aghemo ◽  
E. Degasperi ◽  
E. Galmozzi ◽  
T. J. Urban ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Hepatitis C Therapy ◽  
Anaemia Management ◽  
Inosine Triphosphatase

Inosine Triphosphatase Deficiency does not Predict Anaemia during Ribavirin Containing DAA All Oral Regimens for HCV

2016 ◽  
Vol 64 (2) ◽  
pp. S821-S822
Author(s):  
S. De Nicola ◽  
E. Galmozzi ◽  
A. Aghemo ◽  
R. D’Ambrosio ◽  
E. Degasperi ◽  
...  
Keyword(s):  
Inosine Triphosphatase

Localization of the inosine triphosphatase locus (Itp) on chromosome 2 of the mouse

1987 ◽  
Vol 25 (3-4) ◽  
pp. 267-274 ◽  
Author(s):  
Benjamin A. Taylor ◽  
Donna M. Walls ◽  
Michael J. Wimsatt
Keyword(s):  
Chromosome 2 ◽  
Inosine Triphosphatase

scholarly journals Inhibition of the soluble adenosine triphosphatase from mitochondria by adenylyl imidodiphosphate

1974 ◽  
Vol 143 (3) ◽  
pp. 745-749 ◽  
Author(s):  
Roger D. Philo ◽  
Michael J. Selwyn
Keyword(s):  
Atpase Activity ◽  
Rate Constants ◽  
Binding Sites ◽  
Adenosine Triphosphatase ◽  
Reaction Rate ◽  
Dissociation Reaction ◽  
Reaction Rate Constants ◽  
High Affinity ◽  
Number Of Binding Sites ◽  
Inosine Triphosphatase

1. Adenylyl imidodiphosphate is an inhibitor with high affinity for the soluble ATPase (adenosine triphosphatase) from mitochondria. 2. The reaction of the inhibitor with the ATPase is slow and estimates for the association and dissociation reaction rate constants are given. 3. The number of binding sites for the inhibitor appears to be doubled in the presence of 2,4-dinitrophenol. 4. Adenylyl imidodiphosphate is less effective as an inhibitor of the ATPase activity of this enzyme than of the inosine triphosphatase activity. It is also less effective on the ATPase of frozen-thawed or intact mitochondria and did not inhibit ADP-stimulated respiration by intact mitochondria.

Sign in / Sign up

Export Citation Format

Share Document