The genetic association between osteoprotegerin gene polymorphisms and fracture risk in Chinese Han population

2019 ◽  
Vol 234 (11) ◽  
pp. 20603-20607
Author(s):  
Shuwen Wu ◽  
Zhiyong Li ◽  
Jian Zhang ◽  
Yanxiang Rui
Keyword(s):  
Fracture Risk ◽  
Genetic Association ◽  
Gene Polymorphisms ◽  
Chinese Han Population ◽  
Chinese Han ◽  
Han Population ◽  
Osteoprotegerin Gene

scholarly journals The genetic association between TLR-1, -2, -4, and -6 gene polymorphisms and rheumatoid arthritis (RA) susceptibility in a Chinese Han population

2021 ◽  
Keyword(s):  
Rheumatoid Arthritis ◽  
Genetic Association ◽  
Full Text ◽  
Gene Polymorphisms ◽  
Chinese Han Population ◽  
Chinese Han ◽  
Han Population

Abstract The full text of this preprint has been withdrawn by the authors due to author disagreement with the posting of the preprint. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.

scholarly journals Effects of in IL-1B/IL-1RN variants on the susceptibility to head and neck cancer in a chinese Han population

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yanhai Yin ◽  
Fen Li ◽  
Liangqian Tong ◽  
Chunru Chen ◽  
Bo Yuan
Keyword(s):  
Logistic Regression ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Genetic Association ◽  
Neck Cancer ◽  
Chinese Han Population ◽  
Nucleotide Polymorphisms ◽  
Chinese Han ◽  
Han Population ◽  
Logistic Regression Models

Abstract Background The study aimed to evaluate the relationship of IL-1B/IL-1RN polymorphisms to the predisposition of head and neck cancer (HNC) in a Chinese Han population. Methods Nine single-nucleotide polymorphisms (SNPs) in IL-1B/IL-1RN were genotyped based on Agena MassARRAY platform. Logistic regression models were used to analyze the genetic association between these SNPs and HNC risk by calculating odds ratios (ORs) and 95% confidence intervals (CI). Haplotype analysis were performed using Haploview program and logistic regression model. Results The genetic association between rs1143643 in IL-1B and the higher risk of HNC was found (OR = 1.23, 95% CI 1.04–1.46) in the overall. IL-1RN rs17042888 was related to a reduced risk of HNC in the subjects aged > 46 years (OR = 0.70, 95% CI: 0.50–0.98) and in females (OR = 0.71, 95% CI 0.52–0.98), while rs1143643 increased the predisposition of HNC among females (OR = 1.76, 95% CI 1.13–2.74). Furthermore, rs1143643 had an increased susceptibility to thyroid carcinoma (OR = 1.61, 95% CI 1.10–2.34). Moreover, compared with stage I–II, the frequency of IL-1RN rs452204-AG genotype was lower in patients with stage III–IV. Conclusions IL-1B (rs1143643) and IL-1RN (rs17042888 and rs452204) polymorphisms might be related to the individual susceptibility of HNC in the Chinese Han population. These results might help to improve the understanding of IL-1B and IL-1RN genes in the occurrence of HNC.

scholarly journals Association of interleukin-18 gene polymorphisms with Takayasu arteritis in a Chinese Han population

2020 ◽  
Vol 133 (19) ◽  
pp. 2315-2320
Author(s):  
Dan Wen ◽  
Xian-Liang Zhou ◽  
Xin Du ◽  
Jian-Zeng Dong ◽  
Chang-Sheng Ma
Keyword(s):  
Takayasu Arteritis ◽  
Gene Polymorphisms ◽  
Chinese Han Population ◽  
Interleukin 18 ◽  
Chinese Han ◽  
Han Population

scholarly journals Association between BMP4 gene polymorphisms and eyelid traits in Chinese Han population

2017 ◽  
Vol 6 ◽  
pp. e355-e356 ◽  
Author(s):  
Qian Wang ◽  
Bo Jin ◽  
Xiaoying Luo ◽  
Tao Feng ◽  
Yu Xia ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Chinese Han Population ◽  
Chinese Han ◽  
Han Population

Genetic association analysis between IL9 and coronary artery disease in a Chinese Han population

Cytokine ◽  
2022 ◽  
Vol 150 ◽  
pp. 155761
Author(s):  
Lingfeng Zha ◽  
Jiangtao Dong ◽  
Qianwen Chen ◽  
Yuhua Liao ◽  
Hongsong Zhang ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Genetic Association ◽  
Association Analysis ◽  
Chinese Han Population ◽  
Chinese Han ◽  
Genetic Association Analysis ◽  
Han Population ◽  
Artery Disease
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