The promise of stem cell markers in the diagnosis and therapy of epithelial dysplasia and oral squamous cell carcinoma

2018 ◽  
Vol 233 (11) ◽  
pp. 8499-8507 ◽  
Author(s):  
Farnaz Mohajertehran ◽  
Amirhossein Sahebkar ◽  
Reza Zare ◽  
Nooshin Mohtasham
Keyword(s):  
Squamous Cell Carcinoma ◽  
Stem Cell ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Epithelial Dysplasia ◽  
Stem Cell Markers ◽  
Cell Markers ◽  
Diagnosis And Therapy

scholarly journals Interferon-α Promotes the Expression of Cancer Stem Cell Markers in Oral Squamous Cell Carcinoma

2017 ◽  
Vol 8 (12) ◽  
pp. 2384-2393 ◽  
Author(s):  
Hailong Ma ◽  
Shufang Jin ◽  
Wenyi Yang ◽  
Zhuowei Tian ◽  
Shuli Liu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Stem Cell ◽  
Oral Squamous Cell Carcinoma ◽  
Cancer Stem Cell ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Interferon Α ◽  
Stem Cell Markers ◽  
Cell Markers ◽  
Cancer Stem Cell Markers

scholarly journals Stem cell markers expression evaluation in Oral Squamous Cell Carcinoma

2021 ◽  
Vol 10 (13) ◽  
pp. e314101320840
Author(s):  
Julio Cesar Ramos Cadilho ◽  
Silvia Maria de Carvalho Lyra ◽  
Ana Beatriz Machado Lima ◽  
Carina Maciel da Silva Boghossian ◽  
Cláudia Maria Pereira
Keyword(s):  
Stem Cells ◽  
Squamous Cell Carcinoma ◽  
Stem Cell ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Embryonic Stem ◽  
Tobacco Consumption ◽  
Stem Cell Markers ◽  
Cell Markers

Oral carcinogenesis is a highly complex process. Molecular studies demonstrate that some oral cancers progress from pre-neoplastic lesions. Cancer stem cells (CSCs), a small cellular group within the tumor, have currently received much attention by its self-renewal and tumor differentiation ability. It is considered that CSCs may be responsible for the relapse and metastasis of cancer. CSCs have been reported to express common embryonic stem cells markers such as Nestin and Nanog. The aim of the present study was to identify the presence of Nestin and Nanog markers in patients with oral squamous cell carcinoma (OSCC). Nine samples were collected from patients diagnosed with OSCC and two healthy oral mucosa were used as control. The markers expression in nine OSCC was determined by end-point PCR. The OSCC population analyzed was mostly composed of black and white males, with a mean age of 70.6 years, that reported alcohol and tobacco consumption. Nestin and Nanog stem cell markers were expressed in all OSCCs and normal samples analyzed. As these two markers have already been related to the mechanism of metastasis and relapses in cancer, its expression determination could help to understand the aggressive and invasive nature of OSCC.

scholarly journals Cancer stem cell markers in patterning differentiation and in prognosis of oral squamous cell carcinoma

Tumor Biology ◽  
2017 ◽  
Vol 39 (6) ◽  
pp. 101042831770365 ◽  
Author(s):  
Simple Mohanta ◽  
Gangotri Siddappa ◽  
Sindhu Govindan Valiyaveedan ◽  
Ravindra Dodda Thimmasandra Ramanjanappa ◽  
Debashish Das ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Stem Cell ◽  
Oral Squamous Cell Carcinoma ◽  
Cancer Stem Cell ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Stem Cell Markers ◽  
Cell Markers ◽  
Cancer Stem Cell Markers
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