scholarly journals Impact of YTHDF1 gene polymorphisms on Wilms tumor susceptibility: A five‐center case‐control study

2021 ◽  
Author(s):  
Yanfei Liu ◽  
Huiran Lin ◽  
Rui‐Xi Hua ◽  
Jiao Zhang ◽  
Jiwen Cheng ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Case Control Study ◽  
Wilms Tumor ◽  
Case Control ◽  
Tumor Susceptibility ◽  
Control Study

YTHDC1 gene polymorphisms and Wilms tumor susceptibility in Chinese children: A five-center case-control study

Gene ◽  
2021 ◽  
Vol 783 ◽  
pp. 145571
Author(s):  
Ao Lin ◽  
Rui-Xi Hua ◽  
Mingming Zhou ◽  
Wen Fu ◽  
Jiao Zhang ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Case Control Study ◽  
Wilms Tumor ◽  
Case Control ◽  
Chinese Children ◽  
Tumor Susceptibility ◽  
Control Study

METTL3 polymorphisms and Wilms tumor susceptibility in Chinese children: A five‐center case–control study

2020 ◽  
Vol 22 (11) ◽  
Author(s):  
Ao Lin ◽  
Mingming Zhou ◽  
Rui‐Xi Hua ◽  
Jiao Zhang ◽  
Haixia Zhou ◽  
...  
Keyword(s):  
Case Control Study ◽  
Wilms Tumor ◽  
Case Control ◽  
Chinese Children ◽  
Tumor Susceptibility ◽  
Control Study

scholarly journals Association of KRAS and NRAS gene polymorphisms with Wilms tumor risk: a four-center case-control study

Aging ◽  
2019 ◽  
Vol 11 (5) ◽  
pp. 1551-1563 ◽  
Author(s):  
Wen Fu ◽  
Zhenjian Zhuo ◽  
Rui-Xi Hua ◽  
Kai Fu ◽  
Wei Jia ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Case Control Study ◽  
Wilms Tumor ◽  
Case Control ◽  
Tumor Risk ◽  
Control Study

Role of FTO gene polymorphisms in Wilms tumor predisposition: a five‐center case‐control study

2021 ◽  
Author(s):  
Rui‐Xi Hua ◽  
Wen Fu ◽  
Ao Lin ◽  
Haixia Zhou ◽  
Jiwen Cheng ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Case Control Study ◽  
Wilms Tumor ◽  
Case Control ◽  
Fto Gene ◽  
Control Study

scholarly journals Genetic association of TOLLIP gene polymorphisms and HIV infection: a case-control study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ming-Gui Wang ◽  
Jing Wang ◽  
Jian-Qing He
Keyword(s):  
Hiv Infection ◽  
Gene Polymorphisms ◽  
Case Control Study ◽  
Binary Logistic Regression ◽  
Case Control ◽  
Additive Models ◽  
Chinese Han ◽  
Interacting Protein ◽  
Control Study ◽  
Age And Sex

Abstract Background Previous studies have indicated that host genetic factors play an essential role in immunity to human immunodeficiency virus (HIV) infection. We aimed to investigate the association between the toll-interacting protein (TOLLIP) and mannose-binding lectin 2 (MBL2) genes and HIV infection susceptibility among Chinese Han patients. Methods This is a case-control study. A total of 435 HIV-infected patients and 1013 seronegative healthy individuals were recruited. DNA was extracted from whole blood. Two SNPs in the MBL2 gene (rs7096206 and rs1800450) and three SNPs in the TOLLIP gene (rs5743899, rs3750920, and rs5743867) were selected and genotyped using a SNPscan Kit (Cat#: G0104, Genesky Biotechnologies Inc., Shanghai, China). Odds ratios (ORs) and their 95% confidence intervals (CIs) were calculated using unconditional binary logistic regression. Results A significant association between the minor alleles rs5743899 (C allele) and rs5743867 (G allele) in the TOLLIP gene and susceptibility to HIV infection was found in this study after adjusting for age and sex (Pa = 0.011 and < 0.001, respectively). The rs5743867 in the TOLLIP gene was significantly associated with the risk of HIV infection in dominant, recessive, and additive models when adjusted for age and sex (Pa < 0.05). No significant association was found between MBL2 gene polymorphisms and HIV infection. Conclusion Our study found a statistically significant association between the two SNPs (rs5743867 and rs5743899) in the TOLLIP gene and susceptibility to HIV infection in a Chinese Han population.

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