scholarly journals Correlation between the platelet‐to‐lymphocyte ratio and diabetic foot ulcer in patients with type 2 diabetes mellitus

2021 ◽  
Author(s):  
Kuanxin Zhang ◽  
Sheng Ding ◽  
Xiaoyu Lyu ◽  
Qin Tan ◽  
Zhongjing Wang
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio

scholarly journals Comparison Pai-1 Level in Type 2 Diabetes Mellitus with and Without Diabetic Foot Ulcer

2018 ◽  
Vol 1 (1) ◽  
pp. 1-5
Author(s):  
Alfi Dewi Sholat ◽  
Dairion Gatot ◽  
Savina Handayani ◽  
Andri Iskandar Mardia ◽  
Santi Syafril
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Diabetic Patients ◽  
Significant Difference ◽  
Pai 1

In type 2 diabetes mellitus, there are changes in hemostasis components, including overexpression of PAI-1. By these facts, the authors are interested in conducting the study of PAI-1 level in diabetic patients with and without foot ulcer. Methods: The sample of this research was collected cross-sectionally on 20 type 2 diabetic patients with foot ulcer and 20 without foot ulcer. Blood samples were taken to measure serum PAI-1 level, complete blood count and hemostasis screening test. Results: Statistical analysis showed there are significant differences in hemoglobin, trombosit, Fibrinogen and D-dimer levels in the ulcer and non-ulcer groups but no significant difference in PAI-1 level. Conclusions: No higher PAI – 1 level were found in diabetic foot ulcer group than those without diabetic foot ulcer. There was no significant difference between PAI-1 level and grade of diabetic foot ulcer.

scholarly journals Perilaku self-management dengan kejadian ulkus diabetikum pada pasien diabetes mellitus tipe 2

2020 ◽  
Vol 14 (3) ◽  
pp. 391-400
Author(s):  
Eka Yudha Chrisanto ◽  
Agustama Agustama
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Self Management ◽  
Diabetes Diet ◽  
Diabetes Melitus

Self-management behaviour of diabetic foot ulcer occurrence among patient with  type 2 diabetes mellitusBackground: Diabetes mellitus is one of the silent killers. Indonesia is a country with the 4th largest number of people with diabetes mellitus after China, India, and the United States. In Indonesia people with diabetes mellitus increased from 8.4 million in 2000 to 21.3 million in 2030.Purpose: To determine the self-management behaviour and diabetic foot ulcer occurrence among patient with  type 2 diabetes mellitus.Method: A quantitative research type, with cross sectional analytic and analytical research designs. The population of all people with diabetes mellitus as many as 432 people and a sample of 38 people with a total sampling technique. Data collection using questionnaire sheets and statistical tests used were Chi-Square statistical tests.Results: The frequency distribution of the incidence of diabetic ulcers in patients with type 2 diabetes mellitus, with the category of diabetic ulcers occurring as many as 14 respondents (36.8%). Diabetes diet adherence in patients with diabetes mellitus, with the category of non-compliance with 16 respondents (42.1%). Monitoring blood sugar levels in patients with type 2 diabetes mellitus, with non-routine categories of 15 respondents (39.5%). Physical activity in patients with type 2 diabetes mellitus, with a less good category of 19 respondents (50%).Conclusion: There is a relationship between blood sugar and diabetic ulcer diabetes in type 2 diabetes mellitus patients. There is a relationship between diabetes diet and diabetic ulcer diabetes in type 2 diabetes mellitus patients. There is a relationship between physical activity and the incidence of diabetic ulcers in patients with type 2 diabetes mellitus. It is expected that DM patients can routinely carry out physical and routine activities with high salt levels) in health care facilities and carry out a diabetes diet in accordance with the rules proposed by nutritionists.Keywords: Self-management; Behaviour; Diabetic foot ulcer; Occurrence; Patient; Type 2 diabetes mellitusPendahuluan: Diabetes melitus salah satu the silent killer. Indonesia merupakan negara dengan jumlah penderita diabetes melitus ke-4 terbanyak setelah Cina, India, dan Amerika Serikat.di Indonesia penyandang diabetes melitus mengalami kenaikan dari 8,4 juta pada tahun 2000 menjadi 21,3 juta pada tahun 2030.Tujuan: Diketahui hubungan perilaku self-management dengan kejadian ulkus diabetikum pada pasien diabetes mellitus tipe 2Metode: Jenis penelitian kuantitatif, dengan rancangan penelitian analitik dan pendekatan cross sectional. Populasi seluruh seluruh penderita diabetes melitus sebanyak 432 orang dan sampel sebanyak 38 orang dengan teknik total Sampling. Pengumpulan data menggunakan lembar kuesioner dan Uji statistik yang digunakan adalah uji statistik Chi-Square.Hasil: Distribusi frekuensi kejadian ulkus diabetikum pada penderita diabetes melitus tipe 2, dengan kategori terjadi ulkus diabetikum sebanyak 14 responden (36,8%). Kepatuhan diet diabetes pada pasien diabetes melitus, dengan kategori tidak patuh sebanyak 16 responden (42,1%). Pemantauan kadar gula darah pada pasien diabetes melitus tipe 2, dengan kategori tidak rutin sebanyak 15 responden (39,5%). Aktivitas fisik pada pasien diabetes melitus tipe 2, dengan kategori kurang baik sebanyak 19 responden (50%).Simpulan: Ada hubungan pemantauan kadar gula darah dengan kejadian ulkus diabetikum pada pasien diabetes melitus tipe 2. Ada hubungan kepatuhan diet diabetes dengan kejadian ulkus diabetikum pada pasien diabetes melitus tipe 2. Ada hubungan aktivitas fisik dengan kejadian ulkus diabetikum pada pasien diabetes melitus tipe 2. Diharapkan pasien DM agar rutin melakukan aktivitas fisik  serta rutin mengontrol kadar gula darah pada fasilitas pelayanan kesehatan Serta menjalankan diet diabetes sesuai dengan aturan yang disarankan ahli gizi.

scholarly journals Diabetes control could through platelet-to-lymphocyte ratio in hemograms

2019 ◽  
Vol 65 (1) ◽  
pp. 38-42 ◽  
Author(s):  
Burcin Atak ◽  
Gulali Aktas ◽  
Tuba T. Duman ◽  
Edip Erkus ◽  
M. Zahid Kocak ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Patients ◽  
Platelet To Lymphocyte Ratio ◽  
Type 2 Diabetic Patients ◽  
Lymphocyte Ratio ◽  
Inflammatory Index ◽  
Type 2 Diabetic

SUMMARY OBJECTIVE Association between type 2 diabetes mellitus and inflammation is well-established. We aimed to study platelet-to-lymphocyte ratio (PLR), a novel inflammatory index derived from hemogram, in diabetic patients in comparison to those in healthy volunteers. METHODS Medical data of type 2 diabetics that showed up in general outpatient medical clinics of our institution between February 2017 and August 2017 were recorded and analyzed. RESULTS Median PLR of type 2 diabetic patients was significantly higher than the PLR of healthy controls (p=0.001). Moreover, PLR was significantly and positively correlated with HbA1c (p<0.001, r=0.58), fasting plasma glucose (p<0.001, r=0.49), and c-reactive protein (p=0.003, r=0.30) levels. Type 2 diabetic subjects with proteinuria had significantly higher PLR levels than that of diabetic subjects without proteinuria. CONCLUSION As an inexpensive and easy to use index, PLR may be useful in predicting the development and control levels of type 2 diabetes mellitus. However, its correlation with HbA1c needs to be validated by larger prospective studies.

scholarly journals Platelet to lymphocyte ratio correlates with diabetic foot risk and foot ulcer in patients with type 2 diabetes

2019 ◽  
Vol 66 (10) ◽  
pp. 905-913 ◽  
Author(s):  
Yusuke Mineoka ◽  
Michiyo Ishii ◽  
Yoshitaka Hashimoto ◽  
Aki Yamashita ◽  
Naoto Nakamura ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Diabetic Foot ◽  
Foot Ulcer ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio

scholarly journals The Platelet-to-Lymphocyte Ratio Predicts Diabetic Retinopathy in Type 2 Diabetes Mellitus

2021 ◽  
Author(s):  
Jing Zeng ◽  
Min Chen ◽  
Qiu Feng ◽  
Haiyan Wan ◽  
Jianbo Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Inflammatory Responses ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio

Abstract Introduction:Diabetic retinopathy (DR), as a serious and specific neurovascular complication of DM, remains the leading cause of vision loss and preventable blindness in adults aged 20–74 years. Several studies have indicated that chronic inflammation plays an important role in DR. Emerging evidence suggests that the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR) are novel potential markers of inflammatory responses. However, only a few articles have evaluated the association between these factors and DR.Patients and Methods: The study included 133 patients diagnosed with type 2 diabetes mellitus (T2DM). Retinopathy was graded using the International Clinical Diabetic Retinopathy Disease Severity Scale.Results:The mean NLR, PLR and MLR were significantly higher in patients with DR than in patients without DR (p < 0.001, p = 0.002, and p = 0.003, respectively). In the post hoc analysis, the PDR group had the highest NLR and MLR values among the three groups. Multiple logistic regression showed that the PLR was an independent risk factor for DR (odds ratio [OR]: 1.022, 95% confidence interval [CI]: 1.005–1.040 p = 0.013). Based on the receiver operating characteristic (ROC) curve, the cutoff value of PLR as an indicator for DR diagnosis was projected to be 78.70 and yielded a sensitivity and specificity of 80.7% and 48.9%, respectively, with an area under the curve of 0.669 (95% CI: 0.572–0.765, P = 0.002).Conclusions:Our results suggest that PLR may be an independent risk factor for evaluating DR in patients with type 2 diabetes.

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