scholarly journals MicroRNA profiles in plasma samples from young metabolically healthy obese patients and miRNA‐21 are associated with diastolic dysfunction via TGF‐β1/Smad pathway

2020 ◽  
Vol 34 (6) ◽  
Author(s):  
Pengkang Yang ◽  
Xin Dong ◽  
Yuyang Zhang
Keyword(s):  
Diastolic Dysfunction ◽  
Obese Patients ◽  
Plasma Samples ◽  
Smad Pathway ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy ◽  
Tgf Β1

scholarly journals The prevalence of metabolically healthy obesity according to the sample of the Moscow region

2017 ◽  
Vol 14 (4) ◽  
pp. 51-56 ◽  
Author(s):  
Elena V. Ostrovskaya ◽  
Tatiana I. Romantsova ◽  
Andrei N. Gerasimov ◽  
Tamara E. Novoselova
Keyword(s):  
Metabolic Syndrome ◽  
Carbohydrate Metabolism ◽  
Medical Records ◽  
Density Lipoprotein ◽  
Homa Index ◽  
Obese Patients ◽  
Hip Circumference ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

Introduction. Obesity is a major factor for cardiometabolic risk. However, there is a category of obese patients without disorders of lipid, carbohydrate metabolism and cardiovascular disease metabolically healthy obese (MHO). Aim. Our goal was to investigate the prevalence and characteristics of this phenotype compared to patients with metabolic syndrome (MS). Materials and methods. To evaluate the prevalence of the MHO phenotype we analyzed 389 medical records of females aged 1860 years with obesity. Three types of MHO criteria were used: 1) HOMA index (2.7); 2) IDF-criteria of metabolic syndrome, 2005; 3) the BioSHaRE-EU 2013 criteria (obese patients without any symptoms of MS). We conducted a comparative analysis of anthropometry, status of lipid and carbohydrate metabolism, the functional state of the liver. Results. The MHO prevalence was: 34.5% according to HOMA index, according to the definitions of MS 2005 38.6%, in BioSHaRE-EU 9.6%. In groups of MHO and MS dyslipidemia was observed in 27.3 and 49.5% (p0.05), hypertension in 25% and 71.6% (p0.05), steatogepatosis in 47.7% vs 51.3% (p0.05) of observations, respectively. Among comorbidities the gynecological pathology was most prevalent - 50.8 and 61.4% (p0.05), disorders of carbohydrate metabolism differed significantly in frequency- 6.82 and 39.1% of patients (p0.05). Patients with MHO had a shorter duration of the existence of obesity than MS (18.7 vs. 24 years) (p=0.0004) and less likely to have attempted to reduce weight 85.8% and 91.6%. Average BMI, waist circumference, hip circumference, fasting glucose, total cholesterol, insulin basal, basal C-peptide, HOMA index in groups of MHO and MS differed significantly (p0.05). Median ALT was 20 and 23.2 U/l, AST 20 and 23 U/l, triglycerides 1.1 and 1.8 mmol/l, high-density lipoprotein 1.4 and 1.1 mmol/l, respectively. Conclusions. The MHO prevalence was maximal according to the MS definitions from 2005, and minimal with BioSHaRE-EU criteria. The main analyzed indicators differed significantly in groups MHO and MS. Longer obesity existence in the MS group may suggest an instability of MHO phenotype over time.

Effectiveness of bariatric surgery in metabolically healthy obese patients

2018 ◽  
Author(s):  
Laura Tuneu ◽  
Analia Ramos ◽  
Idoia Genua ◽  
Nicole Stantonyonge ◽  
Francisca Caimari ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Obese Patients ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

scholarly journals Are metabolically healthy obese patients also hemorheologically healthy?

2015 ◽  
Vol 61 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Jean-Frédéric Brun ◽  
Emmanuelle Varlet-Marie ◽  
Christine Fedou ◽  
Eric Raynaud de Mauverger
Keyword(s):  
Obese Patients ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

Visceral white adipose tissue and serum proteomic alternations in metabolically healthy obese patients undergoing bariatric surgery

Cytokine ◽  
2019 ◽  
Vol 115 ◽  
pp. 76-83 ◽  
Author(s):  
Ilias P. Doulamis ◽  
Panagiotis Konstantopoulos ◽  
Aspasia Tzani ◽  
Asier Antoranz ◽  
Angeliki Minia ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Adipose Tissue ◽  
White Adipose Tissue ◽  
Obese Patients ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

Sa1608 Less Liver Fibrosis in Metabolically Healthy Obese Patients Compared With Metabolically Unhealthy Obese Patients With Nonalcoholic Fatty Liver Disease

2016 ◽  
Vol 150 (4) ◽  
pp. S341
Author(s):  
Ylse Gutrierrez-Grobe ◽  
Beatriz Sánchez-Jimenez ◽  
Eva Juárez-Hernández ◽  
Martha Helena Uribe-Ramos ◽  
Martha Helena Ramos-Ostos ◽  
...  
Keyword(s):  
Liver Disease ◽  
Liver Fibrosis ◽  
Fatty Liver ◽  
Nonalcoholic Fatty Liver Disease ◽  
Fatty Liver Disease ◽  
Obese Patients ◽  
Nonalcoholic Fatty Liver ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

scholarly journals Effect of Alternate-Day Fasting on Weight Loss, Weight Maintenance, and Cardioprotection Among Metabolically Healthy Obese Adults

2017 ◽  
Vol 177 (7) ◽  
pp. 930 ◽  
Author(s):  
John F. Trepanowski ◽  
Cynthia M. Kroeger ◽  
Adrienne Barnosky ◽  
Monica C. Klempel ◽  
Surabhi Bhutani ◽  
...  
Keyword(s):  
Weight Loss ◽  
Weight Maintenance ◽  
Obese Adults ◽  
Metabolically Healthy Obese ◽  
Alternate Day Fasting ◽  
Healthy Obese ◽  
Metabolically Healthy
Sign in / Sign up

Export Citation Format

Share Document