scholarly journals The prevalence of metabolically healthy obesity according to the sample of the Moscow region

2017 ◽  
Vol 14 (4) ◽  
pp. 51-56 ◽  
Author(s):  
Elena V. Ostrovskaya ◽  
Tatiana I. Romantsova ◽  
Andrei N. Gerasimov ◽  
Tamara E. Novoselova
Keyword(s):  
Metabolic Syndrome ◽  
Carbohydrate Metabolism ◽  
Medical Records ◽  
Density Lipoprotein ◽  
Homa Index ◽  
Obese Patients ◽  
Hip Circumference ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

Introduction. Obesity is a major factor for cardiometabolic risk. However, there is a category of obese patients without disorders of lipid, carbohydrate metabolism and cardiovascular disease metabolically healthy obese (MHO). Aim. Our goal was to investigate the prevalence and characteristics of this phenotype compared to patients with metabolic syndrome (MS). Materials and methods. To evaluate the prevalence of the MHO phenotype we analyzed 389 medical records of females aged 1860 years with obesity. Three types of MHO criteria were used: 1) HOMA index (2.7); 2) IDF-criteria of metabolic syndrome, 2005; 3) the BioSHaRE-EU 2013 criteria (obese patients without any symptoms of MS). We conducted a comparative analysis of anthropometry, status of lipid and carbohydrate metabolism, the functional state of the liver. Results. The MHO prevalence was: 34.5% according to HOMA index, according to the definitions of MS 2005 38.6%, in BioSHaRE-EU 9.6%. In groups of MHO and MS dyslipidemia was observed in 27.3 and 49.5% (p0.05), hypertension in 25% and 71.6% (p0.05), steatogepatosis in 47.7% vs 51.3% (p0.05) of observations, respectively. Among comorbidities the gynecological pathology was most prevalent - 50.8 and 61.4% (p0.05), disorders of carbohydrate metabolism differed significantly in frequency- 6.82 and 39.1% of patients (p0.05). Patients with MHO had a shorter duration of the existence of obesity than MS (18.7 vs. 24 years) (p=0.0004) and less likely to have attempted to reduce weight 85.8% and 91.6%. Average BMI, waist circumference, hip circumference, fasting glucose, total cholesterol, insulin basal, basal C-peptide, HOMA index in groups of MHO and MS differed significantly (p0.05). Median ALT was 20 and 23.2 U/l, AST 20 and 23 U/l, triglycerides 1.1 and 1.8 mmol/l, high-density lipoprotein 1.4 and 1.1 mmol/l, respectively. Conclusions. The MHO prevalence was maximal according to the MS definitions from 2005, and minimal with BioSHaRE-EU criteria. The main analyzed indicators differed significantly in groups MHO and MS. Longer obesity existence in the MS group may suggest an instability of MHO phenotype over time.

scholarly journals Increased Heart Failure Risk in Normal-Weight People With Metabolic Syndrome Compared With Metabolically Healthy Obese Individuals

2011 ◽  
Vol 58 (13) ◽  
pp. 1343-1350 ◽  
Author(s):  
Christina Voulgari ◽  
Nicholas Tentolouris ◽  
Polychronis Dilaveris ◽  
Dimitris Tousoulis ◽  
Nicholas Katsilambros ◽  
...  
Keyword(s):  
Heart Failure ◽  
Metabolic Syndrome ◽  
Normal Weight ◽  
Metabolically Healthy Obese ◽  
Failure Risk ◽  
Healthy Obese ◽  
Metabolically Healthy

scholarly journals Metabolically healthy obese and metabolic syndrome of the lean: the importance of diet quality. Analysis of MAGNETIC cohort

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Kamila Osadnik ◽  
Tadeusz Osadnik ◽  
Marta Lonnie ◽  
Mateusz Lejawa ◽  
Rafał Reguła ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Diet Quality ◽  
Quality Analysis ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

2061-P: Inflammation Status Is Independent Risk Factor for the Development of Metabolic Syndrome in Both Metabolically Healthy Obese and Nonobese Adults

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 2061-P
Author(s):  
KYU YEON HUR ◽  
MIN SUN CHOI ◽  
SUNG WOON PARK ◽  
SEUNG-EUN LEE ◽  
JIYEON AHN ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Risk Factor ◽  
Independent Risk Factor ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

Effectiveness of bariatric surgery in metabolically healthy obese patients

2018 ◽  
Author(s):  
Laura Tuneu ◽  
Analia Ramos ◽  
Idoia Genua ◽  
Nicole Stantonyonge ◽  
Francisca Caimari ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Obese Patients ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

Magnesium intake is associated with the metabolically healthy obese phenotype

2021 ◽  
pp. jim-2021-001841
Author(s):  
Fernando Guerrero-Romero ◽  
Gerardo Morales-Gurrola ◽  
Lucía Preza-Rodríguez ◽  
Alejandra Gómez-Barrientos ◽  
Ana I Olivas-Martínez ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Abdominal Obesity ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Magnesium Intake ◽  
Metabolically Healthy Obese ◽  
Low Hdl ◽  
Healthy Obese ◽  
Metabolically Healthy

Although magnesium intake is inversely associated with the risk of metabolic abnormalities, whether magnesium intake plays a role on metabolically healthy obese (MHO) phenotype has not been explored. Therefore, the purpose of this study was to determine whether the magnesium intake is associated with the MHO phenotype. Apparently, healthy women and men aged 20–65 years with obesity were enrolled in a cross-sectional study. Subjects were allocated into MHO (n=124) and metabolically unhealthy obese (MUO) (n=123) groups. MHO phenotype was defined by abdominal obesity (waist circumference ≥90 cm in men and ≥80 cm in women) and none, or not more than one of the following risk factors: triglyceride levels ≥150 mg/dL; high-density lipoprotein cholesterol (HDL-C) levels <40 mg/dL in men and <50 mg/dL in women; fasting glucose ≥100 mg/dL; and systolic blood pressure ≥130 mm Hg and/or diastolic blood pressure ≥85 mm Hg. The MUO individuals were characterized by abdominal obesity and the presence of two or more of the aforementioned criteria. The proportion of individuals with high blood pressure (40.7% vs 5.6%, p<0.001), hyperglycemia (69.1% vs 16.9%, p<0.001), hypertriglyceridemia (84.6% vs 36.3%, p<0.001), and low HDL-C (51.2% vs 12.9%, p<0.001) was significantly higher in the MUO individuals as compared with individuals in the MHO group. The logistic regression analysis adjusted by sex and age showed that dietary magnesium intake is significantly associated with the MHO phenotype (OR=1.17; 95% CI 1.07 to 1.25, p=0.005). Our results show that magnesium intake is significantly associated with the MHO phenotype.

scholarly journals Metabolically healthy obese women have longer telomere length than obese women with metabolic syndrome

PLoS ONE ◽  
2017 ◽  
Vol 12 (4) ◽  
pp. e0174945 ◽  
Author(s):  
Andrea E. Iglesias Molli ◽  
Julieta Panero ◽  
Patricia C. Dos Santos ◽  
Claudio D. González ◽  
Jorge Vilariño ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Telomere Length ◽  
Obese Women ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

scholarly journals Are metabolically healthy obese patients also hemorheologically healthy?

2015 ◽  
Vol 61 (1) ◽  
pp. 39-46 ◽  
Author(s):  
Jean-Frédéric Brun ◽  
Emmanuelle Varlet-Marie ◽  
Christine Fedou ◽  
Eric Raynaud de Mauverger
Keyword(s):  
Obese Patients ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

scholarly journals Association of Metabolically Healthy Obesity and Future Depression: Using National Health Insurance System Data in Korea from 2009–2017

2020 ◽  
Vol 18 (1) ◽  
pp. 63
Author(s):  
Yongseok Seo ◽  
Seungyeon Lee ◽  
Joung-Sook Ahn ◽  
Seongho Min ◽  
Min-Hyuk Kim ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Health Insurance ◽  
National Health Insurance ◽  
National Health ◽  
Metabolic Status ◽  
National Health Insurance System ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy

(1) Background: The health implications associated with the metabolically healthy obese (MHO) phenotype, in particular related to symptoms of depression, are still not clear. the purpose of this study is to check whether depression and metabolic status are relevant by classifying them into four groups in accordance with the MHO diagnostic standard. Other impressions seen were the differences between sexes and the effects of the MHO on the occurrence of depression. (2) Methods: A sample of 3,586,492 adult individuals from the National Health Insurance Database of Korea was classified into four categories by their metabolic status and body mass index: (1) metabolically healthy non-obese (MHN); (2) metabolically healthy obese (MHO); (3) metabolically unhealthy non-obese (MUN); and (4) metabolically unhealthy obese (MUO). Participants were followed for six to eight years for new incidences of depression. The statistical significance of the general characteristics of the four groups, as well as the mean differences in metabolic syndrome risk factors, was assessed with the use of a one-way analysis of variance (ANOVA). (3) Results: The MHN ratio in women was higher than in men (men 39.3%, women 55.2%). In both men and women, depression incidence was the highest among MUO participants (odds ratio (OR) = 1.01 in men; OR = 1.09 in women). It was concluded as well that, among the risk factors of metabolic syndrome, waist circumference was the most related to depression. Among the four groups, the MUO phenotype was the most related to depression. Furthermore, in women participants, MHO is also related to a higher risk of depressive symptoms. These findings indicate that MHO is not a totally benign condition in relation to depression in women. (4) Conclusion: Therefore, reducing metabolic syndrome and obesity patients in Korea will likely reduce the incidence of depression.

Visceral white adipose tissue and serum proteomic alternations in metabolically healthy obese patients undergoing bariatric surgery

Cytokine ◽  
2019 ◽  
Vol 115 ◽  
pp. 76-83 ◽  
Author(s):  
Ilias P. Doulamis ◽  
Panagiotis Konstantopoulos ◽  
Aspasia Tzani ◽  
Asier Antoranz ◽  
Angeliki Minia ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Adipose Tissue ◽  
White Adipose Tissue ◽  
Obese Patients ◽  
Metabolically Healthy Obese ◽  
Healthy Obese ◽  
Metabolically Healthy
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