scholarly journals Clinical value of jointly detection pleural fluid Midkine, pleural fluid adenosine deaminase, and pleural fluid carbohydrate antigen 125 in the identification of nonsmall cell lung cancer-associated malignant pleural effusion

2018 ◽  
Vol 32 (8) ◽  
pp. e22576
Author(s):  
Fan Zhang ◽  
Junjun Wang ◽  
Xiaoyong Zheng ◽  
Lijuan Hu ◽  
Jie Chen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Pleural Effusion ◽  
Adenosine Deaminase ◽  
Pleural Fluid ◽  
Cell Lung Cancer ◽  
Malignant Pleural Effusion ◽  
Nonsmall Cell Lung Cancer ◽  
Carbohydrate Antigen ◽  
Clinical Value ◽  
Carbohydrate Antigen 125

scholarly journals Does cytoreduction surgery and hyperthermic intrathoracic chemotherapy prolong survival in patients with N0–N1 nonsmall cell lung cancer and malignant pleural effusion?

2019 ◽  
Vol 28 (153) ◽  
pp. 190018 ◽  
Author(s):  
Marcello Migliore ◽  
Marco Nardini
Keyword(s):  
Lung Cancer ◽  
Systematic Review ◽  
Pleural Effusion ◽  
Cell Lung Cancer ◽  
Malignant Pleural Effusion ◽  
Single Case ◽  
Case Reports ◽  
Controlled Trial ◽  
Nonsmall Cell Lung Cancer ◽  
Debulking Surgery

IntroductionDebulking surgery and hyperthermic intrathoracic chemotherapy (HITHOC) has been successfully used in the treatment of thoracic tumours. Few authors report on the feasibility of its use in patients with lung cancer and malignant pleural effusion. The aim of this study was to evaluate the efficacy and results of debulking surgery and HITHOC in the treatment of selected patients with nonsmall cell lung cancer (NSCLC) and malignant pleural effusion.MethodsA systematic review was conducted in MEDLINE in accordance with PRISMA guidelines. The word search included: “hyperthermic intrathoracic chemotherapy and/or HITHOC or hyperthermic intrapleural”. Inclusion criteria were only those studies reporting a sufficient amount of data on HITHOC and surgery for lung cancer. Single case reports and review articles were excluded.Results20 articles were selected as they related to the topic of HITHOC and lung cancer. Most were from China (n=8) and Japan (n=6). Only four out of the 20 articles had sufficient data for this review. In total, data for 21 patients were collected. Debulking surgery ranged from wedge resection to pneumonectomy and pleurectomy. Mean survival was 27 months and median survival was 18 months (range 1–74 months). 13 patients out of 21 (62%) were alive at 1 year and six (28.5%) were alive at 2 years. 10 patients were still alive at the time of the respective publication in the 21 patients included. Systemic toxicity and treatment-related mortality were nil. There were insufficient data to perform a meta-analysis.ConclusionAlthough reported survival in this systematic review is encouraging, available evidence concerning debulking surgery and HITHOC in N0–N1 NSCLC with malignant pleural effusion is weak. Better evidence in the form of a randomised controlled trial is mandatory.

scholarly journals Malignant Pleural Effusion at Presentation in Patients with Small-Cell Lung Cancer

Respiration ◽  
2019 ◽  
Vol 98 (3) ◽  
pp. 198-202 ◽  
Author(s):  
Samira Shojaee ◽  
Inderjit Singh ◽  
Ian Solsky ◽  
Patrick Nana-Sinkam
Keyword(s):  
Lung Cancer ◽  
Pleural Effusion ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Malignant Pleural Effusion ◽  
Small Cell ◽  
Small Cell Lung

scholarly journals Permanent pleural catheter (PPC) for malignant pleural effusion (PE) in advanced non-small cell lung cancer (NSCLC)

2019 ◽  
Vol 30 ◽  
pp. ii63
Author(s):  
M. Martinez Kareaga ◽  
N. Urbieta-Macazaga ◽  
C. Sanchez-Vieco ◽  
L. Tomás-López ◽  
I. Intxaurbe-Etxebarria ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Pleural Effusion ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Malignant Pleural Effusion ◽  
Small Cell ◽  
Small Cell Lung ◽  
Pleural Catheter

scholarly journals Malignant pleural effusion as a predictor of the efficacy of anti‐PD‐1 antibody in patients with non‐small cell lung cancer

2019 ◽  
Vol 10 (4) ◽  
pp. 815-822 ◽  
Author(s):  
Ryota Shibaki ◽  
Shuji Murakami ◽  
Yuki Shinno ◽  
Yuji Matsumoto ◽  
Yasushi Goto ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Pleural Effusion ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Malignant Pleural Effusion ◽  
Small Cell ◽  
Small Cell Lung
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