scholarly journals Comparing calculated free testosterone with total testosterone for screening and diagnosing late-onset hypogonadism in aged males: A cross-sectional study

2016 ◽  
Vol 31 (5) ◽  
pp. e22073 ◽  
Author(s):  
Zhangshun Liu ◽  
Jie Liu ◽  
Xiaohong Shi ◽  
Lihong Wang ◽  
Yan Yang ◽  
...  
Keyword(s):  
Late Onset ◽  
Free Testosterone ◽  
Cross Sectional Study ◽  
Total Testosterone ◽  
Sectional Study ◽  
Cross Sectional ◽  
Late Onset Hypogonadism

MP84-12 DOES CALCULATED FREE TESTOSTERONE OVERCOME TOTAL TESTOSTERONE IN PROTECTING FROM SEXUAL SYMPTOMS IMPAIRMENT? FINDINGS OF A CROSS-SECTIONAL STUDY

2017 ◽  
Vol 197 (4S) ◽  
Author(s):  
Luca Boeri ◽  
Paolo Capogrosso ◽  
Eugenio Ventimiglia ◽  
Walter Cazzaniga ◽  
Filippo Pederzoli ◽  
...  
Keyword(s):  
Free Testosterone ◽  
Cross Sectional Study ◽  
Total Testosterone ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sexual Symptoms

Does Calculated Free Testosterone Overcome Total Testosterone in Protecting From Sexual Symptom Impairment? Findings of a Cross-Sectional Study

2017 ◽  
Vol 14 (12) ◽  
pp. 1549-1557 ◽  
Author(s):  
Luca Boeri ◽  
Paolo Capogrosso ◽  
Eugenio Ventimiglia ◽  
Walter Cazzaniga ◽  
Filippo Pederzoli ◽  
...  
Keyword(s):  
Free Testosterone ◽  
Cross Sectional Study ◽  
Total Testosterone ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals The Epidemiological Characteristics of Late-Onset Hypogonadism in Chinese Middle-Aged and Elderly Men: Two Cross-Sectional Studies in the Same Community

2020 ◽  
Vol 14 (6) ◽  
pp. 155798832097799
Author(s):  
Shan-Jie Zhou ◽  
Ming-Jia Zhao ◽  
Yi-Hong Yang ◽  
Di Guan ◽  
Zhi-Guang Li ◽  
...  
Keyword(s):  
Late Onset ◽  
Community Dwelling ◽  
Total Testosterone ◽  
Middle Aged ◽  
Cross Sectional ◽  
Cutoff Values ◽  
Significant Difference ◽  
Cross Sectional Studies ◽  
Late Onset Hypogonadism ◽  
Epidemiological Characteristics

The purpose of this study was to investigate the prevalence and epidemiological characteristics of late-onset hypogonadism (LOH) in middle-aged and elderly Chinese men. Two cross-sectional studies were conducted at 5-year intervals in community-dwelling men living in the same area. A total of 1472 (Study 1, S1) and 944 (Study 2, S2) men aged 40–69 years old were recruited as subjects. Subjects were evaluated through combining serum reproductive hormone levels with the Androgen Deficiency in Aging Males (ADAM) questionnaire and the Aging Males’ Symptoms (AMS) scale. A significant difference was found in mean testosterone deficiency (TD) prevalence between S1 and S2, using either serum total testosterone (TT; 14.02% vs. 6.36%) or serum calculated free testosterone (cFT; 43.69% vs. 16.53%) cutoff values. According to the S1 or S2 data, the mean prevalence of LOH was 37.85%/15.47% in the positive ADAM test and 15.42%/9.43% in the positive AMS test ( p < .01). According to classifications of TD based on gonadal status, the prevalence of secondary TD (27.34%) was higher than the primary (16.36%) and compensated (15.42%) TD in S1 ( p < .01). However, there were significant differences among the prevalence of primary (6.89%), secondary (9.64%), and compensated (27.65%) TD in S2 ( p < .05). Different types of testosterone levels, TD cutoff values, and questionnaires influenced the prevalence of TD and LOH. The serum FT cutoff value was an optimal threshold for evaluating and diagnosing TD and LOH, whose prevalence increased gradually with male aging.

Admixture analysis of age at onset in older patients with schizophrenia spectrum disorders

2020 ◽  
Vol 32 (6) ◽  
pp. 781-785
Author(s):  
Maureen M. J. Smeets-Janssen ◽  
Idan M. Aderka ◽  
Paul D. Meesters ◽  
Sjors Lange ◽  
Sigfried Schouws ◽  
...  
Keyword(s):  
Late Onset ◽  
Age At Onset ◽  
Cross Sectional Study ◽  
Data Driven ◽  
Admixture Analysis ◽  
Schizophrenia Spectrum Disorders ◽  
Sectional Study ◽  
Cross Sectional ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders

ABSTRACTThe nature of schizophrenia spectrum disorders with an onset in middle or late adulthood remains controversial. The aim of our study was to determine in patients aged 60 and older if clinically relevant subtypes based on age at onset can be distinguished, using admixture analysis, a data-driven technique. We conducted a cross-sectional study in 94 patients aged 60 and older with a diagnosis of schizophrenia or schizoaffective disorder. Admixture analysis was used to determine if the distribution of age at onset in this cohort was consistent with one or more populations of origin and to determine cut-offs for age at onset groups, if more than one population could be identified. Results showed that admixture analysis based on age at onset demonstrated only one normally distributed population. Our results suggest that in older schizophrenia patients, early- and late-onset ages form a continuum.

scholarly journals A comparison of sexual desire in opiate-dependent men receiving methadone and buprenorphine maintenance treatment

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Anne Yee ◽  
Huai Seng Loh ◽  
Huai Heng Loh ◽  
Shahrzad Riahi ◽  
Chong Guan Ng ◽  
...  
Keyword(s):  
Sexual Desire ◽  
Rating Scale ◽  
Methadone Maintenance ◽  
Cross Sectional Study ◽  
Opiate Dependence ◽  
Total Testosterone ◽  
Sectional Study ◽  
Cross Sectional ◽  
Male Patients ◽  
Dependent Patient

Abstract Background Methadone is an effective therapy for opiate dependence. However, one of the commonest side effects is sexual dysfunction among male patients. Buprenorphine is an alternative to methadone. This study aimed to compare sexual desire among opiate-dependent male patients on buprenorphine (BMT) and methadone maintenance therapy (MMT). Methods This cross-sectional study involved 126 male opiate-dependent patient who were tested for total testosterone (TT) and prolactin levels, and were interviewed and completed the Sexual Desire Inventory-2 (SDI-2), Malay language of International Index of Erectile Function (Mal-IIEF-15) and the Malay version of the self-rated Montgomery-Asberg Depression Rating Scale (MADRS-BM) questionnaires. Results There were 95 (75.4%) patients on MMT and 31 (24.6%) on BMT. Patients on MMT scored significantly lower in the sexual desire domain (Mal-IIEF-15 scores) (p < 0.01), dyadic sexual desire (p = 0.04) and TT plasma level (p < 0.01) when compared to BMT group after controlling all the confounders. Conclusions Patients on MMT are associated with lower sexual desire when compared with patients on BMT. Smoking may further lower testosterone and, hence, sexual desire in those already on methadone.

Executive functions and basic symptoms in adolescent antisocial behavior: A cross-sectional study on an Italian sample of late-onset offenders

2014 ◽  
Vol 55 (3) ◽  
pp. 631-638 ◽  
Author(s):  
Maria Rosaria A. Muscatello ◽  
Giuseppe Scimeca ◽  
Gianluca Pandolfo ◽  
Umberto Micò ◽  
Vincenzo M. Romeo ◽  
...  
Keyword(s):  
Executive Functions ◽  
Antisocial Behavior ◽  
Late Onset ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Basic Symptoms ◽  
Italian Sample
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