scholarly journals Reference Intervals of Serum Sodium, Potassium, and Chlorine in Chinese Han Population and Comparison of Two ISE Methods

2014 ◽  
Vol 29 (3) ◽  
pp. 226-234 ◽  
Author(s):  
Keke Jia ◽  
Chuanbao Zhang ◽  
Xianzhang Huang ◽  
Lanlan Wang ◽  
Xiaoke Hao ◽  
...  
2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Wenjia Guo ◽  
Qi Zhou ◽  
Yanan Jia ◽  
Jiancheng Xu

Age- and sex-specific reference intervals (RIs) for myocardial enzyme activity of children and adolescents are not available in China. Our study aimed to establish age- and gender-related RIs for AST, LDH, CK, and CKMB activity in healthy Chinese Han population aged 1∼<18 years. Healthy Han children and adolescents (n = 6322, 1∼<18 years old) were assessed from completed questionnaires and defined criteria from communities and schools in 5 administrative districts of Jilin Province from September 2017 to December 2018. Measurements of AST, LDH, CK, and CKMB activity were performed on the VITROS 5600 Integrated System. Percentiles of enzyme activity were completed by LMS. RIs were established by Medcalc according to the EP28-A3c guidelines issued by the Clinical and Laboratory Standards Institute. AST declined rapidly during 1∼<6 years and had been subsided during 11∼<18 years, though LDH decreased at a steady rate. CK activity stabilized while CKMB showed a downward trend. Sex differences started after age 12 when males presented higher results. There were significant differences comparing with domestic and other countries’ experiments which applied similar methodologies. Enzymes were associated with age and sex, while age had greater impact. We established age- and sex-specific RIs of serum AST, LDH, CK, and CKMB activities for Chinese children and adolescents using the VITROS 5600 Integrated System for the first time. These data will lay the groundwork for the next horizon in pediatric RIs as well as improve test result interpretation for pediatric illness.


2018 ◽  
Vol 56 (4) ◽  
pp. 642-648 ◽  
Author(s):  
Zanlin Mai ◽  
Xiaoxia Li ◽  
Zelin Cui ◽  
Wenqi Wu ◽  
Yongda Liu ◽  
...  

Abstract Background: The aim of the study was to establish reference intervals for 24-h urinary stone risk factors in the healthy Chinese Han population. Methods: From May 2013 to July 2014, we collected and analyzed 24-h urine samples from healthy adult Han population during a cross-sectional study across China. The protocol for analysis of 24-h urine included volume, pH, oxalate, citrate, sodium, potassium, chloride, calcium, phosphorous, creatinine, urate, magnesium, the ion activity products of calcium oxalate (AP(CaOx) indexs) and calcium phosphate (AP(CaP) indexs). We calculated the reference intervals according to the Clinical and Laboratory Standards Institute (CLSI) 2008 guidelines and compared them with those recorded in other studies. Results: A total of 132 male and 123 female healthy subjects with a mean (SD, range) age of 52.4 (15.2, 19–89) years were eligible in the final analysis. Men had higher 24-h excretion of creatinine, calcium, urate and phosphorus and lower levels of citrate, magnesium, chloride, sodium and potassium than women. AP(CaOx) indexs and AP(CaP) indexs were significantly higher among men than women. When urinary findings were compared with the reference intervals, most of our data showed a high abnormality rate, especially for creatinine, calcium, citrate, magnesium, chloride, sodium and potassium. Conclusions: The present study revealed the normal metabolic status for stone risk factors of the Chinese Han population. It is therefore necessary for each country or region to define their own reference intervals for comparison of stone risk factors between patients and healthy subjects.


2020 ◽  
Vol 70 (7) ◽  
pp. 1130-1139
Author(s):  
Guolong Tu ◽  
Wenliang Zhan ◽  
Yao Sun ◽  
Jiamin Wu ◽  
Zichao Xiong ◽  
...  

2014 ◽  
Vol 34 (10) ◽  
pp. 1729-1736 ◽  
Author(s):  
Xinglin Yang ◽  
Ming Li ◽  
Liya Wang ◽  
Zhongdan Hu ◽  
Yuanchao Zhang ◽  
...  

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