Syntheses, Structures and Anticancer Activity of NNO-Tridentate Schiff Base Copper(II) Complexes

2014 ◽  
Vol 61 (12) ◽  
pp. 1333-1340 ◽  
Author(s):  
Rong-Kai Lin ◽  
Cho-Han Hsu ◽  
Chin-I Chiu ◽  
Ying-Ju Lai ◽  
a Feng-Jie Lai ◽  
...  
2021 ◽  
Author(s):  
Nazanin Kordestani ◽  
Hadi Amiri Rudbari ◽  
Alexandra R Fernandes ◽  
Luís R Raposo ◽  
André Luz ◽  
...  

To investigate the effect of different halogen substituents, leaving groups and the flexibility of ligand on the anticancer activity of copper complexes, sixteen copper(II) complexes with eight different tridentate Schiff-base...


2019 ◽  
Vol 48 (40) ◽  
pp. 15220-15230 ◽  
Author(s):  
Katja Dankhoff ◽  
Madeleine Gold ◽  
Luisa Kober ◽  
Florian Schmitt ◽  
Lena Pfeifer ◽  
...  

We report 15 new Cu(ii) complexes with tridentate NNO β-acylenamino ligands derived from 2-picolylamine and bearing up to three alkyl, alkoxy, alkoxycarbonyl, or (pseudo)halide substituents.


2016 ◽  
Vol 26 (6) ◽  
pp. 1927-1938 ◽  
Author(s):  
Ayman A. Abdel Aziz ◽  
Rania G. Mohamed ◽  
Fatma M. Elantabli ◽  
Samir M. El-Medani

2018 ◽  
Vol 42 (3) ◽  
pp. 1634-1641 ◽  
Author(s):  
Samim Khan ◽  
Stephen Sproules ◽  
Louise S. Natrajan ◽  
Klaus Harms ◽  
Shouvik Chattopadhyay

Two new dinuclear Schiff base copper(ii) complexes have been synthesized and characterized. Copper(ii) centres are ferromagnetically coupled in1and antiferromagnetically coupled in2.


INDIAN DRUGS ◽  
2019 ◽  
Vol 56 (03) ◽  
pp. 12-17
Author(s):  
Manpreet Kaur ◽  
S. Singh ◽  

A new series of 2,5-disubstituted-1,3,4-oxadiazole derivatives has been synthesized with the help of different aromatic benzaldehydes and final compounds were characterized by FTIR and 1H NMR. 2,5- disubstituted-1,3,4-oxadiazole derivatives were synthesized by the reaction of Schiff base derivatives with 2,5-disubstituted-1,3,4-oxadiazoles. All the synthesized compounds were screened for their anticancer activity. These compounds were evaluated for their anticancer activity against various cancer cell lines. Five of the compounds possessed good to moderate anti-cancer activity. Three of the synthesized compounds i.e. 6a, 6f and 6g were found to possess maximum growth inhibition. The order for the % control growth inhibition of MCF-7 was found to be 6a>6f>6g>5b>6h, as shown in Table II-VI.


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