Long noncoding RNA CCAT2 functions as a competitive endogenous RNA to regulate FOXC1 expression by sponging miR‐23b‐5p in lung adenocarcinoma

2018 ◽  
Vol 120 (5) ◽  
pp. 7998-8007 ◽  
Author(s):  
Guo‐dong Hu ◽  
Cheng‐xiang Wang ◽  
Hong‐ying Wang ◽  
Ya‐qin Wang ◽  
Shuo Hu ◽  
...  
Human Cell ◽  
2021 ◽  
Vol 34 (2) ◽  
pp. 478-490
Author(s):  
Xinyue Chen ◽  
Huimin Chen ◽  
Miaowen Liu ◽  
Jianping Xiong ◽  
Zhiwang Song

Oncotarget ◽  
2016 ◽  
Vol 7 (38) ◽  
pp. 62474-62489 ◽  
Author(s):  
Jing Chen ◽  
Kai Zhang ◽  
Haizhu Song ◽  
Rui Wang ◽  
Xiaoyuan Chu ◽  
...  

2021 ◽  
Vol 15 (4) ◽  
pp. 257-271
Author(s):  
Yankuo Zhu ◽  
Yinchuan Zhu ◽  
Yingchao Liu ◽  
Yanru Liu ◽  
Xiaoyu Chen

Aim: To investigate correlations of long noncoding RNA metastasis-associated lung adenocarcinoma transcript 1 (lnc-MALAT1) and its target microRNAs with clinical features and restenosis risk in coronary heart disease (CHD) patients post drug-eluting stent-percutaneous coronary intervention (DES-PCI). Materials & methods: A total of 274 CHD patients undergoing DES-PCI were enrolled, pre-operative plasma samples were obtained to detect lnc-MALAT1, miR-125b, miR-146a, miR-203 by RT-qPCR; 2-year restenosis was determined by quantitative coronary angiography. Results: Lnc-MALAT1 negatively correlated with miR-125b, miR-146a and miR-203. Furthermore, lnc-MALAT1, miR-125b, miR-146a and miR-203 correlated with diabetes mellitus, hyperuricemia, lesion properties, cholesterol, inflammation and cardiac function indexes. Additionally, lnc-MALAT1 was increased, while miR-125b and miR-146a were decreased in patients with 2-year restenosis than patients without 2-year restenosis; however, miR-203 did not differ. Conclusion: Lnc-MALAT1 and its target miRNAs might help manage restenosis risk in CHD patients post DES-PCI.


2020 ◽  
Vol 125 ◽  
pp. 109989 ◽  
Author(s):  
Xiaoqian Mu ◽  
Hongbo Wu ◽  
Jie Liu ◽  
Xiufeng Hu ◽  
Huijuan Wu ◽  
...  

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