Transfer of a normal human chromosome 11 suppresses tumorigenicity of some but not all tumor cell lines

1990 ◽  
Vol 42 (3) ◽  
pp. 135-142 ◽  
Author(s):  
Mitsuo Oshimura ◽  
Hiroyuki Kugoh ◽  
Minoru Koi ◽  
Motoyuki Shimizu ◽  
Hideto Yamada ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Tumor Cell ◽  
Cell Lines ◽  
Tumor Cell Lines ◽  
Chromosome 11 ◽  
Normal Human

Cytostasis of tumor cell lines by granulocytes from cancer patients and normal human donors

1981 ◽  
Vol 28 (2) ◽  
pp. 119-124 ◽  
Author(s):  
S. Korec ◽  
R. B. Herberman ◽  
G. B. Cannon ◽  
J. Reid ◽  
J. A. Braatz
Keyword(s):  
Tumor Cell ◽  
Cancer Patients ◽  
Cell Lines ◽  
Tumor Cell Lines ◽  
Normal Human

TNF-α-mediated apoptosis in normal human prostate epithelial cells and tumor cell lines

2004 ◽  
Vol 203 (2) ◽  
pp. 145-154 ◽  
Author(s):  
Dharam P. Chopra ◽  
Raymond E. Menard ◽  
Jakub Januszewski ◽  
Raymond R. Mattingly
Keyword(s):  
Epithelial Cells ◽  
Tumor Cell ◽  
Cell Lines ◽  
Human Prostate ◽  
Tumor Cell Lines ◽  
Prostate Epithelial Cells ◽  
Tnf Α ◽  
Normal Human

Complementation of a DNA repair deficiency in six human tumor cell lines by chromosome 11

1992 ◽  
Vol 88 (5) ◽  
pp. 524-528 ◽  
Author(s):  
R. Parshad ◽  
F. M. Price ◽  
M. Oshimura ◽  
J. C. Barrett ◽  
H. Satoh ◽  
...  
Keyword(s):  
Dna Repair ◽  
Tumor Cell ◽  
Cell Lines ◽  
Human Tumor ◽  
Tumor Cell Lines ◽  
Chromosome 11 ◽  
Human Tumor Cell ◽  
Human Tumor Cell Lines ◽  
Repair Deficiency ◽  
Dna Repair Deficiency

Introduction of a normal human chromosome 11 into a Wilms' tumor cell line controls its tumorigenic expression

Science ◽  
1987 ◽  
Vol 236 (4798) ◽  
pp. 175-180 ◽  
Author(s):  
B. Weissman ◽  
P. Saxon ◽  
Pasquale ◽  
G. Jones ◽  
A. Geiser ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Tumor Cell ◽  
Cell Line ◽  
Wilms Tumor ◽  
Tumor Cell Line ◽  
Chromosome 11 ◽  
Normal Human

Normal human chromosome 11 suppresses tumorigenicity of human cervical tumor cell line SiHa

1989 ◽  
Vol 2 (1) ◽  
pp. 12-21 ◽  
Author(s):  
Minoru Koi ◽  
Hiroyuki Morita ◽  
Hideto Yamada ◽  
Hitoshi Satoh ◽  
J. Carl Barrett ◽  
...  
Keyword(s):  
Human Chromosome ◽  
Tumor Cell ◽  
Cell Line ◽  
Tumor Cell Line ◽  
Cervical Tumor ◽  
Chromosome 11 ◽  
Normal Human

Normal human thyroid cells, BCPAP, and TPC-1 thyroid tumor cell lines display different profile in both basal and TNF-α-induced CXCL8 secretion

Endocrine ◽  
2015 ◽  
Vol 54 (1) ◽  
pp. 123-128 ◽  
Author(s):  
Francesca Coperchini ◽  
Patrizia Pignatti ◽  
Paola Leporati ◽  
Andrea Carbone ◽  
Laura Croce ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Thyroid Tumor ◽  
Human Thyroid ◽  
Tumor Cell Lines ◽  
Thyroid Cells ◽  
Cxcl8 Secretion ◽  
Tnf Α ◽  
Normal Human

Interaction of Human Tumor Cells with Human Platelets and the Coagulation System

1983 ◽  
Vol 50 (03) ◽  
pp. 726-730 ◽  
Author(s):  
Hamid Al-Mondhiry ◽  
Virginia McGarvey ◽  
Kim Leitzel
Keyword(s):  
Tumor Cell ◽  
Tumor Cells ◽  
Cell Lines ◽  
Human Tumor ◽  
Human Platelets ◽  
Factor Vii ◽  
Coagulation System ◽  
Breast Adenocarcinoma ◽  
Activate Factor ◽  
Tumor Cell Lines

SummaryThis paper reports studies on the interaction between human platelets, the plasma coagulation system, and two human tumor cell lines grown in tissue culture: Melanoma and breast adenocarcinoma. The interaction was monitored through the use of 125I- labelled fibrinogen, which measures both thrombin activity generated by cell-plasma interaction and fibrin/fibrinogen binding to platelets and tumor cells. Each tumor cell line activates both the platelets and the coagulation system simultaneously resulting in the generation of thrombin or thrombin-like activity. The melanoma cells activate the coagulation system through “the extrinsic pathway” with a tissue factor-like effect on factor VII, but the breast tumor seems to activate factor X directly. Both tumor cell lines activate platelets to “make available” a platelet- derived procoagulant material necessary for the conversion of prothrombin to thrombin. The tumor-derived procoagulant activity and the platelet aggregating potential of cells do not seem to be inter-related, and they are not specific to malignant cells.

Sign in / Sign up

Export Citation Format

Share Document