Hyaline cartilage formation and enchondral ossification modeled with KUM5 and OP9 chondroblasts

2007 ◽  
Vol 100 (5) ◽  
pp. 1240-1254 ◽  
Author(s):  
Tadashi Sugiki ◽  
Taro Uyama ◽  
Masashi Toyoda ◽  
Hideo Morioka ◽  
Shoen Kume ◽  
...  
Keyword(s):  
Hyaline Cartilage ◽  
Cartilage Formation ◽  
Enchondral Ossification

scholarly journals Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem cells

2015 ◽  
Vol 36 (3) ◽  
pp. 179-186 ◽  
Author(s):  
Taku SAITO ◽  
Fumiko YANO ◽  
Daisuke MORI ◽  
Manabu KAWATA ◽  
Kazuto HOSHI ◽  
...  
Keyword(s):  
B Cells ◽  
Hyaline Cartilage ◽  
Cartilage Formation ◽  
Induced Pluripotent

scholarly journals A cell‐free approach with a supporting biomaterial in the form of dispersed microspheres induces hyaline cartilage formation in a rabbit knee model

2020 ◽  
Vol 108 (4) ◽  
pp. 1428-1438 ◽  
Author(s):  
Javier Zurriaga Carda ◽  
Maria L. Lastra ◽  
Carmen M. Antolinos‐Turpin ◽  
Rosa M. Morales‐Román ◽  
María Sancho‐Tello ◽  
...  
Keyword(s):  
Hyaline Cartilage ◽  
Cartilage Formation ◽  
Knee Model ◽  
Rabbit Knee ◽  
A Cell

scholarly journals Chondrolipoma of the stomach

2019 ◽  
Vol 12 (3) ◽  
pp. e228757
Author(s):  
Reuben J Chen ◽  
Yi Qiu Sun ◽  
Michael W Hii ◽  
Mary Ann Johnson
Keyword(s):  
Adipose Tissue ◽  
Rare Variant ◽  
Hyaline Cartilage ◽  
Wedge Resection ◽  
Postoperative Recovery ◽  
Cartilage Formation ◽  
Mature Adipose Tissue ◽  
First Case ◽  
Uneventful Postoperative Recovery ◽  
Mesenchymal Neoplasm

Chondrolipoma, a rare variant of a lipoma, is a benign mesenchymal neoplasm characterised by mature adipocytes with neoplastic hyaline cartilage formation. We describe the first case of a gastric chondrolipoma. The tumour was completely excised via laparoscopic gastric wedge resection with uneventful postoperative recovery. Histology of the tumour demonstrates mature adipose tissue and benign cartilage with patchy calcification.

scholarly journals Intermittent hypoxia inhibits mandibular cartilage growth with reduced TGF-β and SOX9 expressions in neonatal rats

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kochakorn Lekvijittada ◽  
Jun Hosomichi ◽  
Hideyuki Maeda ◽  
Haixin Hong ◽  
Chidsanu Changsiripun ◽  
...  
Keyword(s):  
Bone Mineral ◽  
Intermittent Hypoxia ◽  
Hyaline Cartilage ◽  
Body Weight Gain ◽  
Mandibular Condyle ◽  
Neonatal Rats ◽  
Sprague Dawley ◽  
Cartilage Growth ◽  
Condylar Cartilage ◽  
Sprague Dawley Rats

AbstractIntermittent hypoxia (IH) has been associated with skeletal growth. However, the influence of IH on cartilage growth and metabolism is unknown. We compared the effects of IH on chondrocyte proliferation and maturation in the mandibular condyle fibrocartilage and tibial hyaline cartilage of 1-week-old male Sprague–Dawley rats. The rats were exposed to normoxic air (n = 9) or IH at 20 cycles/h (nadir, 4% O2; peak, 21% O2; 0% CO2) (n = 9) for 8 h each day. IH impeded body weight gain, but not tibial elongation. IH also increased cancellous bone mineral and volumetric bone mineral densities in the mandibular condylar head. The mandibular condylar became thinner, but the tibial cartilage did not. IH reduced maturative and increased hypertrophic chondrocytic layers of the middle and posterior mandibular cartilage. PCR showed that IH shifted proliferation and maturation in mandibular condyle fibrocartilage toward hypertrophic differentiation and ossification by downregulating TGF-β and SOX9, and upregulating collagen X. These effects were absent in the tibial growth plate hyaline cartilage. Our results showed that neonatal rats exposed to IH displayed underdeveloped mandibular ramus/condyles, while suppression of chondrogenesis marker expression was detected in the growth-restricted condylar cartilage.

scholarly journals A Case Report of Spindle Cell Carcinoma with Osteoid and Cartilage Formation in the Tongue

Reports ◽  
2021 ◽  
Vol 4 (1) ◽  
pp. 5
Author(s):  
Sawako Ono ◽  
Takuma Makino ◽  
Hiroyuki Yanai ◽  
Hotaka Kawai ◽  
Kiyofumi Takabatake ◽  
...  
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Spindle Cell ◽  
Spindle Cell Carcinoma ◽  
Cartilage Formation ◽  
And Cartilage

Spindle cell carcinoma (SCSCC) with osteoid and/or cartilage formation in the head and neck is rare; only one case was reported in the tongue. Herein, we report an SCSCC with osteoid and cartilage formation of the tongue developed in an 85-year-old man, and then review the report.

The Reliability of Ultrasound in the Assessment of Hyaline Cartilage in Rheumatoid Arthritis and Healthy Metacarpal Heads

2020 ◽  
Author(s):  
Edoardo Cipolletta ◽  
Emilio Filippucci ◽  
Andrea Di Matteo ◽  
Giulia Tesei ◽  
Micaela Ana Cosatti ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Scoring System ◽  
Quantitative Assessment ◽  
Hyaline Cartilage ◽  
Scoring Systems ◽  
Thickness Measurement ◽  
Cartilage Thickness ◽  
Observer Agreement ◽  
Very High Frequency ◽  
Observer Reliability

Abstract Purpose i) To assess the inter- and intra-observer reliability of ultrasound (US) in the evaluation of the hyaline cartilage (HC) of the metacarpal head (MH) in patients with rheumatoid arthritis (RA) and in healthy subjects (HS) both qualitatively and quantitatively. ii) To calculate the smallest detectable difference (SDD) of the MH cartilage thickness measurement. iii) To correlate the qualitative scoring system and the quantitative assessment. Materials and Methods US examination was performed on 280 MHs of 20 patients with RA and 15 HS using a very high frequency probe (up to 22 MHz). HC status was evaluated both qualitatively (using a five-grade scoring system) and quantitatively (using the average value of the longitudinal and transverse measures). The HC of MHs from II to V metacarpophalangeal joint of both hands were scanned independently on the same day by two rheumatologists to assess inter-observer reliability. All subjects were re-examined using the same scanning protocol and the same US setting by one sonographer after a week to assess intra-observer reliability. Results The inter-observer agreement and intra-observer agreement were moderate to substantial (k = 0.66 and k = 0.73) for the qualitative scoring system and high (ICC = 0.93 and ICC = 0.94) for the quantitative assessment. The SDD of the MH cartilage thickness measurement was 0.09 mm. A significant correlation between the two scoring systems was found (r = –0.35; p < 0.001). Conclusion The present study describes the main methodological issues of HC assessment. Using a standardized protocol, both the qualitative and the quantitative scoring systems can be reliable.

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