Doxazosin and erlotinib have anticancer effects in the endometrial cancer cell and important roles in ERα and Wnt/β‐catenin signaling pathways

Comparative transcriptome analysis between patient and endometrial cancer cell lines to determine common signaling pathways and markers linked to cancer progression

Oncotarget ◽

10.18632/oncotarget.28161 ◽

2021 ◽

Vol 12 (26) ◽

pp. 2500-2513

Author(s):

Madelaine J. Cho-Clark ◽

Gauthaman Sukumar ◽

Newton Medeiros Vidal ◽

Sorana Raiciulescu ◽

Mario G. Oyola ◽

...

Keyword(s):

Endometrial Cancer ◽

Signaling Pathways ◽

Cell Lines ◽

Cancer Cell ◽

Cancer Progression ◽

Transcriptome Analysis ◽

Cancer Cell Lines ◽

Comparative Transcriptome ◽

Endometrial Cancer Cell ◽

Comparative Transcriptome Analysis

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Estrogen induces endometrial cancer cell proliferation and invasion by regulating the fat mass and obesity-associated gene via PI3K/AKT and MAPK signaling pathways

Cancer Letters ◽

10.1016/j.canlet.2011.12.033 ◽

2012 ◽

Vol 319 (1) ◽

pp. 89-97 ◽

Cited By ~ 50

Author(s):

Zhenbo Zhang ◽

Dongmei Zhou ◽

Yunli Lai ◽

Yongjuan Liu ◽

Xiang Tao ◽

...

Keyword(s):

Cell Proliferation ◽

Endometrial Cancer ◽

Signaling Pathways ◽

Cancer Cell ◽

Fat Mass ◽

Mapk Signaling ◽

Cancer Cell Proliferation ◽

Endometrial Cancer Cell ◽

Proliferation And Invasion ◽

Mapk Signaling Pathways

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Review for "Pharmacologic inhibition of Akt in combination with chemotherapeutic agents effectively induces apoptosis in ovarian and endometrial cancer cell lines"

10.1002/1878-0261.12888/v1/review2 ◽

2020 ◽

Keyword(s):

Endometrial Cancer ◽

Cell Lines ◽

Cancer Cell ◽

Cancer Cell Lines ◽

Chemotherapeutic Agents ◽

Endometrial Cancer Cell ◽

Pharmacologic Inhibition

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Decision letter for "Pharmacologic inhibition of Akt in combination with chemotherapeutic agents effectively induces apoptosis in ovarian and endometrial cancer cell lines"

10.1002/1878-0261.12888/v2/decision1 ◽

2020 ◽

Keyword(s):

Endometrial Cancer ◽

Cell Lines ◽

Cancer Cell ◽

Cancer Cell Lines ◽

Chemotherapeutic Agents ◽

Endometrial Cancer Cell ◽

Pharmacologic Inhibition

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Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)36630-9 ◽

1994 ◽

Vol 269 (20) ◽

pp. 14367-14370 ◽

Cited By ~ 9

Author(s):

A. Umar ◽

J.C. Boyer ◽

D.C. Thomas ◽

D.C. Nguyen ◽

J.I. Risinger ◽

...

Keyword(s):

Endometrial Cancer ◽

Microsatellite Instability ◽

Mismatch Repair ◽

Cell Lines ◽

Cancer Cell ◽

Cancer Cell Lines ◽

Endometrial Cancer Cell ◽

Defective Mismatch Repair

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Perfluorooctanoic acid induces human Ishikawa endometrial cancer cell migration and invasion through activation of ERK/mTOR signaling

Oncotarget ◽

10.18632/oncotarget.11684 ◽

2016 ◽

Vol 7 (41) ◽

pp. 66558-66568 ◽

Cited By ~ 9

Author(s):

Zhinan Ma ◽

Xiaoqiu Liu ◽

Fujun Li ◽

Yixong Wang ◽

Yang Xu ◽

...

Keyword(s):

Endometrial Cancer ◽

Cell Migration ◽

Cancer Cell ◽

Perfluorooctanoic Acid ◽

Mtor Signaling ◽

Migration And Invasion ◽

Cancer Cell Migration ◽

Endometrial Cancer Cell ◽

Cell Migration And Invasion

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Mutations in tumor suppressor gene, FBXW7, are associated with carboplatin resistance in endometrial cancer cell lines

Gynecologic Oncology ◽

10.1016/j.ygyno.2015.07.059 ◽

2015 ◽

Vol 139 (1) ◽

pp. 194 ◽

Cited By ~ 1

Author(s):

Alexandre Buckley de Meritens ◽

Ayesha Joshi ◽

Christopher Miller ◽

Lora Hedrick Ellenson ◽

Divya Gupta

Keyword(s):

Endometrial Cancer ◽

Tumor Suppressor ◽

Tumor Suppressor Gene ◽

Cell Lines ◽

Cancer Cell ◽

Cancer Cell Lines ◽

Suppressor Gene ◽

Endometrial Cancer Cell

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381 Efficacy of specific FGFR inhibitors against gatekeeper resistance mutations and shared mechanism of cell death in FGFR2-dependent endometrial cancer cell lines

European Journal of Cancer ◽

10.1016/s0959-8049(14)70507-6 ◽

2014 ◽

Vol 50 ◽

pp. 122

Author(s):

L. Packer ◽

S. Byron ◽

S. Stehbens ◽

D. Loch ◽

F. Dehkhoda ◽

...

Keyword(s):

Cell Death ◽

Endometrial Cancer ◽

Cell Lines ◽

Cancer Cell ◽

Cancer Cell Lines ◽

Resistance Mutations ◽

Endometrial Cancer Cell

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Ligand-Activated Peroxisome Proliferator-Activated Receptor β/δ Modulates Human Endometrial Cancer Cell Survival

Hormones and Cancer ◽

10.1007/s12672-013-0157-7 ◽

2013 ◽

Vol 4 (6) ◽

pp. 358-370 ◽

Cited By ~ 4

Author(s):

J. J. Ma ◽

D. Monsivais ◽

M. T. Dyson ◽

J. S. Coon ◽

S. Malpani ◽

...

Keyword(s):

Endometrial Cancer ◽

Cell Survival ◽

Cancer Cell ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Endometrial Cancer Cell ◽

Cancer Cell Survival

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RETRACTED ARTICLE: LncRNA CTBP1-AS2 sponges miR-216a to upregulate PTEN and suppress endometrial cancer cell invasion and migration

Journal of Ovarian Research ◽

10.1186/s13048-020-00639-2 ◽

2020 ◽

Vol 13 (1) ◽

Cited By ~ 6

Author(s):

Qing-an-zi Wang ◽

Yongxiu Yang ◽

Xiaolei Liang

Keyword(s):

Endometrial Cancer ◽

Cancer Cell ◽

Cell Invasion ◽

Cardiomyocyte Hypertrophy ◽

Cancer Cell Invasion ◽

Endometrial Cancer Cell ◽

Invasion And Migration ◽

Tcga Dataset ◽

And Migration ◽

Rna Interaction

Abstract Background Although lncRNA CTBP1-AS2 has been functionally analyzed only in cardiomyocyte hypertrophy and diabetes, analysis of TCGA dataset revealed its downregulation in endometrial carcinoma (EC), indicating its involvement in EC. Results In this study we found that CTBP1-AS2 was downregulated in EC and correlated with poor survival. MiR-216a might form base pairs with CTBP1-AS2 based on RNA-RNA interaction, which was confirmed by luciferase activity assay. Interestingly, upregulation of PTEN was observed after CTBP1-AS2 overexpression. Transwell assay showed that CTBP1-AS2 and PTEN overexpression led to decreased cancer cell invasion and migration and reduced enhancing effects of miR-216a on cell invasion and migration. It was known that miR-216a targeted PTEN. Conclusion Therefore, CTBP1-AS2 may sponge miR-216a to upregulate PTEN, thereby suppressing endometrial cancer cell invasion and migration.

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