Improvement of insulin resistance via increase of GLUT4 and PPARγ in metabolic syndrome-induced rats treated with omega-3 fatty acid orl-carnitine

2018 ◽  
Vol 32 (11) ◽  
pp. e22218 ◽  
Author(s):  
Eman Adel Zayed ◽  
Afaf A. AinShoka ◽  
Kamal A. El Shazly ◽  
Hekma A. Abd El Latif
Author(s):  
Salvador García-López ◽  
Rosina E. Villanueva Arriaga ◽  
Oralia Nájera Medina ◽  
Carmen Paulina Rodríguez López ◽  
Lauro Figueroa-Valverde ◽  
...  

AbstractBackground:This study sought to investigate the effects of omega (ω)-3 polyunsaturated fatty acid (PUFA) supplementation on the lipid profiles and glucose (GLU) levels of overweight (OW) schoolchildren with metabolic syndrome (MS).Methods:Thirty-nine OW schoolchildren with MS, including 19 girls and 20 boys, received 1-month of dietary supplementation with gel capsules containing ω-3 fatty acids. Fasting lipid profiles and GLU levels were measured before and after supplementation.Results:Both sexes of OW schoolchildren with MS who received daily supplementation with 2.4 g of ω-3 fatty acids for 1 month displayed improved lipid profiles, reduced fasting GLU levels and reduced blood pressure (BP).Conclusions:These findings support the addition of omega-3 fatty acid supplementation to programs aiming to improve the metabolic status of OW children with MS, although additional research on the longer-term safety and efficacy of this treatment in this population is required.


Metabolism ◽  
2003 ◽  
Vol 52 (1) ◽  
pp. 30-34 ◽  
Author(s):  
Masataka Kusunoki ◽  
Kazuhiko Tsutsumi ◽  
Tsutomu Hara ◽  
Hitoshi Ogawa ◽  
Takao Nakamura ◽  
...  

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