Al2O3Nanoparticles Induce Mitochondria-Mediated Cell Death and Upregulate the Expression of Signaling Genes in Human Mesenchymal Stem Cells

2012 ◽  
Vol 26 (11) ◽  
pp. 469-476 ◽  
Author(s):  
Ali A. Alshatwi ◽  
Periasamy Vaiyapuri Subbarayan ◽  
E. Ramesh ◽  
Amal A. Al-Hazzani ◽  
Mohammed A. Alsaif ◽  
...  
Keyword(s):  
Stem Cells ◽  
Cell Death ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells

Human mesenchymal stem cells protect neutrophils from serum-deprived cell death

2011 ◽  
Vol 35 (12) ◽  
pp. 1247-1251 ◽  
Author(s):  
Maryam Maqbool ◽  
Sharmili Vidyadaran ◽  
Elizabeth George ◽  
Rajesh Ramasamy
Keyword(s):  
Stem Cells ◽  
Cell Death ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells

scholarly journals Statin-induced calcification in human mesenchymal stem cells is cell death related

2009 ◽  
Vol 13 (11-12) ◽  
pp. 4465-4473 ◽  
Author(s):  
Laszlo Kupcsik ◽  
Thomas Meurya ◽  
Matthias Flury ◽  
Martin Stoddart ◽  
Mauro Alini
Keyword(s):  
Stem Cells ◽  
Cell Death ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells

scholarly journals Programmed cell death 4 inhibits proliferation and differentiation and induces apoptosis of human mesenchymal stem cells through suppressing the Wnt/β-catenin pathway

RSC Advances ◽  
2017 ◽  
Vol 7 (43) ◽  
pp. 26566-26573 ◽  
Author(s):  
Yang Liu ◽  
Dongyue Su ◽  
Tao Song
Keyword(s):  
Stem Cells ◽  
Cell Death ◽  
Mesenchymal Stem Cells ◽  
Programmed Cell Death ◽  
Human Mesenchymal Stem Cells ◽  
Proliferation And Differentiation ◽  
Programmed Cell Death 4

PDCD4 was closely related to the proliferation and the apoptosis of OP-hMSCs in osteoporosis.

scholarly journals The sensitivity of human mesenchymal stem cells to vibration and cold storage conditions representative of cold transportation

2012 ◽  
Vol 9 (75) ◽  
pp. 2503-2515 ◽  
Author(s):  
N. I. Nikolaev ◽  
Y. Liu ◽  
H. Hussein ◽  
D. J. Williams
Keyword(s):  
Stem Cells ◽  
Cell Death ◽  
Mesenchymal Stem Cells ◽  
Cell Viability ◽  
Cold Storage ◽  
Human Mesenchymal Stem Cells ◽  
Peak Acceleration ◽  
Trypan Blue Exclusion Method ◽  
Peak Displacement ◽  
Membrane Rupture

In the current study, the mechanical and hypothermic damage induced by vibration and cold storage on human mesenchymal stem cells (hMSCs) stored at 2–8°C was quantified by measuring the total cell number and cell viability after exposure to vibration at 50 Hz (peak acceleration 140 m s −2 and peak displacement 1.4 mm), 25 Hz (peak acceleration 140 m s −2 , peak displacement 5.7 mm), 10 Hz (peak acceleration 20 m s −2 , peak displacement 5.1 mm) and cold storage for several durations. To quantify the viability of the cells, in addition to the trypan blue exclusion method, the combination of annexin V-FITC and propidium iodide was applied to understand the mode of cell death. Cell granularity and a panel of cell surface markers for stemness, including CD29, CD44, CD105 and CD166, were also evaluated for each condition. It was found that hMSCs were sensitive to vibration at 25 Hz, with moderate effects at 50 Hz and no effects at 10 Hz. Vibration at 25 Hz also increased CD29 and CD44 expression. The study further showed that cold storage alone caused a decrease in cell viability, especially after 48 h, and also increased CD29 and CD44 and attenuated CD105 expressions. Cell death would most likely be the consequence of membrane rupture, owing to necrosis induced by cold storage. The sensitivity of cells to different vibrations within the mechanical system is due to a combined effect of displacement and acceleration, and hMSCs with a longer cold storage duration were more susceptible to vibration damage, indicating a coupling between the effects of vibration and cold storage.

Proliferation and multi-differentiation potentials of human mesenchymal stem cells on thermoresponsive PDMS surfaces grafted with PNIPAAm

2010 ◽  
Vol 30 (6) ◽  
pp. 455-455 ◽  
Author(s):  
Dongyan Shi ◽  
Dan Ma ◽  
Feiqing Dong ◽  
Chen Zong ◽  
Liyue Liu ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Human Mesenchymal Stem Cells
Sign in / Sign up

Export Citation Format

Share Document