Muscle Strength and Physical Performance Improve Fracture Risk Prediction beyond Garvan and FRAX : The Osteoporotic Fractures in Men ( MrOS ) Study

2021 ◽  
Author(s):  
Dima Alajlouni ◽  
Thach Tran ◽  
Dana Bliuc ◽  
Robert D. Blank ◽  
Peggy M. Cawthon ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Fracture Risk ◽  
Physical Performance ◽  
Risk Prediction ◽  
Osteoporotic Fractures ◽  
Fracture Risk Prediction

scholarly journals 64 Association between Risk of Osteoporotic Fractures with Spinal Morphology, Muscle Strength and Physical Performance

2019 ◽  
Vol 48 (Supplement_4) ◽  
pp. iv13-iv17
Author(s):  
Siew Kuan Chua ◽  
Devinder ◽  
KA Singh ◽  
Bala S Rajaratnam ◽  
Sabarul Afian Mokhtar ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Fracture Risk ◽  
Physical Performance ◽  
Tracking System ◽  
Osteoporotic Fractures ◽  
Limited Information ◽  
Functional Impairments ◽  
Mineral Density ◽  
Increased Risk ◽  
Study Results

Abstract Osteoporotic related fractures (OF) are associated with functional impairments and declined quality of life. Low bone mineral density is one of the main risk factor for OF. However, there is limited information regarding the association of spinal morphology, muscle strength and physical performance with OF. The aim of the study was to examine association between risk of osteoporotic fractures with spinal morphology (thoracolumbar curvature and back extensors muscle strength), muscle strength and physical performance. 105 adults aged 50 years and above (69.3+ 8.5 years) were recruited for this cross-sectional study from a spine orthopaedic clinic. Thoracolumbar curvature, back extensors (BEMS) and handgrip (HGS) muscle strength were measured using an electromagnetic tracking system, a load-cell system and hand-held dynamometer respectively. Physical performance was assessed using Short Physical Performance Battery (SPPB). Participants were categorised for major osteoporotic fracture risk (major OF) with cut-point 10% using fracture risk calculator (FRAX®) with BMD. Student t-test analysis demonstrated that there is a significant (p<0.05) difference between participants with low risk and moderate to high risk of major OF for BEMS, HGS, and SPPB. Adjusted logistic models (forward and backward), showed that lower HGS and physical performance were associated with increased risk of major OF (HGS: OR = 0.18 [95% CI, 0.07–0.48]; SPPB: OR = 0.32[95% CI, 0.13–0.80]). Our study results suggest that declined muscle strength and physical performance is associated with higher risk of OF. It is important to promote optimum muscle strength and physical performance among older adults in the prevention of OF.

scholarly journals Developing Novel Prognostic Biomarkers for Multivariate Fracture Risk Prediction Algorithms

2012 ◽  
Vol 91 (3) ◽  
pp. 204-214 ◽  
Author(s):  
Ernest K. Poku ◽  
Mark R. Towler ◽  
Niamh M. Cummins ◽  
Jeff D. Newman
Keyword(s):  
Fracture Risk ◽  
Risk Prediction ◽  
Prognostic Biomarkers ◽  
Prediction Algorithms ◽  
Fracture Risk Prediction

Fracture Risk Prediction by Non-BMD DXA Measures: the 2015 ISCD Official Positions Part 2: Trabecular Bone Score

2015 ◽  
Vol 18 (3) ◽  
pp. 309-330 ◽  
Author(s):  
Barbara C. Silva ◽  
Susan B. Broy ◽  
Stephanie Boutroy ◽  
John T. Schousboe ◽  
John A. Shepherd ◽  
...  
Keyword(s):  
Fracture Risk ◽  
Trabecular Bone ◽  
Risk Prediction ◽  
Trabecular Bone Score ◽  
Fracture Risk Prediction

Metastatic Burst Fracture Risk Prediction Using Biomechanically Based Equations

2004 ◽  
Vol 419 ◽  
pp. 83-90 ◽  
Author(s):  
Sandra E Roth ◽  
Payam Mousavi ◽  
Joel Finkelstein ◽  
Edward Chow ◽  
Hans Kreder ◽  
...  
Keyword(s):  
Fracture Risk ◽  
Risk Prediction ◽  
Burst Fracture ◽  
Fracture Risk Prediction

4:41 Metastatic burst fracture risk prediction

2002 ◽  
Vol 2 (5) ◽  
pp. 75
Author(s):  
Sandra Roth ◽  
Payam Mousavi ◽  
Henry Ahn ◽  
Joel Finkelstein ◽  
Edward Chow ◽  
...  
Keyword(s):  
Fracture Risk ◽  
Risk Prediction ◽  
Burst Fracture ◽  
Fracture Risk Prediction
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