scholarly journals Relationships between calcified atherosclerotic plaque and bone mineral density in African Americans with type 2 diabetes

2011 ◽  
Vol 26 (7) ◽  
pp. 1554-1560 ◽  
Author(s):  
Jasmin Divers ◽  
Thomas C Register ◽  
Carl D Langefeld ◽  
Lynne E Wagenknecht ◽  
Donald W Bowden ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
African Americans ◽  
Bone Mineral ◽  
Atherosclerotic Plaque ◽  
Mineral Density

scholarly journals Bone Mineral Density and Progression of Subclinical Atherosclerosis in African-Americans With Type 2 Diabetes

2016 ◽  
Vol 101 (11) ◽  
pp. 4135-4141 ◽  
Author(s):  
Lynne E. Wagenknecht ◽  
Jasmin Divers ◽  
Thomas C. Register ◽  
Gregory B. Russell ◽  
Donald W. Bowden ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
African Americans ◽  
Bone Mineral ◽  
Subclinical Atherosclerosis ◽  
Mineral Density

scholarly journals Plasma FGF23 and Calcified Atherosclerotic Plaque in African Americans with Type 2 Diabetes Mellitus

2015 ◽  
Vol 42 (6) ◽  
pp. 391-401 ◽  
Author(s):  
Barry I. Freedman ◽  
Jasmin Divers ◽  
Gregory B. Russell ◽  
Donald W. Bowden ◽  
J. Jeffrey Carr ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
African American ◽  
Coronary Artery ◽  
African Americans ◽  
Kidney Function ◽  
Vascular Calcification ◽  
Atherosclerotic Plaque ◽  
Mineral Density

Background: Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone implicated in disorders of serum phosphorus concentration and vitamin D. The role of FGF23 in vascular calcification remains controversial. Methods: Relationships between FGF23 and coronary artery calcified atherosclerotic plaque (CAC), aortoiliac calcified plaque (CP), carotid artery CP, volumetric bone mineral density (vBMD), albuminuria, and estimated glomerular filtration rate (eGFR) were determined in 545 African Americans with type 2 diabetes (T2D) and preserved kidney function in African American-Diabetes Heart Study participants. Generalized linear models were fitted to test associations between FGF23 and cardiovascular, bone, and renal phenotypes, and change in measurements over time, adjusting for age, gender, African ancestry proportion, body mass index, diabetes duration, hemoglobin A1c, blood pressure, renin-angiotensin-system inhibitors, statins, calcium supplements, serum calcium, and serum phosphate. Results: The sample was 56.7% female with a mean (SD) age of 55.6 (9.6) years, diabetes duration of 10.3 (8.2) years, eGFR 90.9 (22.1) ml/min/1.73 m2, urine albumin:creatinine ratio (UACR) 151 (588) (median 13) mg/g, plasma FGF23 161 (157) RU/ml, and CAC 637 (1,179) mg. In fully adjusted models, FGF23 was negatively associated with eGFR (p < 0.0001) and positively associated with UACR (p < 0.0001) and CAC (p = 0.0006), but not with carotid CP or aortic CP. Baseline FGF23 concentration did not associate with changes in vBMD or CAC after a mean of 5.1 years follow-up. Conclusions: Plasma FGF23 concentrations were independently associated with subclinical coronary artery disease, albuminuria, and kidney function in the understudied African American population with T2D. Findings support relationships between FGF23 and vascular calcification, but not between FGF23 and bone mineral density, in African Americans lacking advanced nephropathy.

Bone Mineral Density and Fractures in Urban African Americans With Type 2 Diabetes

2014 ◽  
Vol 17 (3) ◽  
pp. 424
Author(s):  
S. Madduri ◽  
S.S. Shenoy ◽  
G.L. Nunlee-Bland ◽  
R. Cherqaoui ◽  
C. Bunton-Young ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
African Americans ◽  
Bone Mineral ◽  
Mineral Density

scholarly journals Calcified atherosclerotic plaque and bone mineral density in type 2 diabetes: The diabetes heart study

Bone ◽  
2008 ◽  
Vol 42 (1) ◽  
pp. 43-52 ◽  
Author(s):  
J. Jeffrey Carr ◽  
Thomas C. Register ◽  
Fang-Chi Hsu ◽  
Kurt Lohman ◽  
Leon Lenchik ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
Bone Mineral ◽  
Atherosclerotic Plaque ◽  
Mineral Density ◽  
Heart Study ◽  
Diabetes Heart Study

Bone mineral density in male patients with type 2 diabetes mellitus, with and without hypogonadism

2017 ◽  
Author(s):  
Agathi Vasileiou ◽  
Ioanna Karathanassi ◽  
Parthena Navrozidou ◽  
Marianna Vlychou ◽  
Georgios Koukoulis ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Bone Mineral ◽  
Mineral Density ◽  
Male Patients

scholarly journals Link between vitamin B12, type 2 diabetes mellitus, and bone mineral density in elderly patients

2015 ◽  
Vol 6 (4) ◽  
pp. 120-124 ◽  
Author(s):  
Moatassem S. Amer ◽  
Randa Ali-Labib ◽  
Tamer M. Farid ◽  
Doha Rasheedy ◽  
Mohammad F. Tolba
Keyword(s):  
Diabetes Mellitus ◽  
Bone Mineral Density ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Elderly Patients ◽  
Vitamin B12 ◽  
Bone Mineral ◽  
Mineral Density
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