scholarly journals Effects of Denosumab, Alendronate, or Denosumab Following Alendronate on Bone Turnover, Calcium Homeostasis, Bone Mass and Bone Strength in Ovariectomized Cynomolgus Monkeys

2015 ◽  
Vol 30 (4) ◽  
pp. 657-669 ◽  
Author(s):  
Paul J Kostenuik ◽  
Susan Y Smith ◽  
Rana Samadfam ◽  
Jacquelin Jolette ◽  
Lei Zhou ◽  
...  
Keyword(s):  
Bone Mass ◽  
Bone Turnover ◽  
Bone Strength ◽  
Calcium Homeostasis ◽  
Cynomolgus Monkeys

scholarly journals Erratum to Fluoride Treatment Increased Serum IGF-1 Bone Turnover, and Bone Mass, But Not Bone Strength, in Rabbits

1997 ◽  
Vol 61 (4) ◽  
pp. 349-349 ◽  
Author(s):  
C. H. Turner ◽  
L. P. Garetto ◽  
A. J. Dunipace ◽  
W. Zhang ◽  
M. E. Wilson ◽  
...  
Keyword(s):  
Bone Mass ◽  
Bone Turnover ◽  
Bone Strength ◽  
Fluoride Treatment

Fluoride Treatment Increased Serum IGF-1, Bone Turnover, and Bone Mass, but Not Bone Strength, in Rabbits

1997 ◽  
Vol 61 (1) ◽  
pp. 77-83 ◽  
Author(s):  
C. H. Turner ◽  
L. P. Garetto ◽  
A. J. Dunipace ◽  
W. Zhang ◽  
M. E. Wilson ◽  
...  
Keyword(s):  
Bone Mass ◽  
Bone Turnover ◽  
Bone Strength ◽  
Fluoride Treatment

scholarly journals Central Neural Regulation of Parathyroid Hormone

2020 ◽  
Author(s):  
L. Zhang ◽  
N. Liu ◽  
J. Shao ◽  
D. Gao ◽  
Y. Liu ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Bone Mass ◽  
Bone Turnover ◽  
Paraventricular Nucleus ◽  
Calcium Homeostasis ◽  
Neural Regulation ◽  
Brain Nuclei ◽  
Trabecular Bone Mass ◽  
Serum Pth ◽  
Stimulation Of

AbstractParathyroid hormone (PTH) is one of the most important hormones responsible for bone turnover and calcium homeostasis, however, the mechanism underlying central neural regulation of PTH in mammals remains largely unknown. In this study, we identified the subfornical organ (SFO) and the paraventricular nucleus (PVN) as two important brain nuclei responded to serum PTH and calcium changes. Using chemogenetics, we found that serum PTH was suppressed by stimulation of SFOGABA neurons followed by a decrease in trabecular bone mass. Conversely, stimulation of SFOVGlut neurons promoted serum PTH and bone mass. The paraventricular nucleus (PVN) is downstream of the SFO, and chemogenetic activation of PVNCaMKII and PVNVGlut neurons induced an increase in serum PTH. These findings reveal important central neural nodes and will advance our understanding of the central neural regulation of PTH at the molecular, cellular and circuit level.

scholarly journals Effects of the Antiepileptic Drugs Phenytoin, Gabapentin, and Levetiracetam on Bone Strength, Bone Mass, and Bone Turnover in Rats

2017 ◽  
Vol 40 (11) ◽  
pp. 1934-1940 ◽  
Author(s):  
Junkichi Kanda ◽  
Nobuo Izumo ◽  
Yoshiko Kobayashi ◽  
Kenji Onodera ◽  
Taketoshi Shimakura ◽  
...  
Keyword(s):  
Bone Mass ◽  
Bone Turnover ◽  
Antiepileptic Drugs ◽  
Bone Strength

scholarly journals Short- to Mid-Term Effects of Ovariectomy on Bone Turnover, Bone Mass and Bone Strength in Rats

2007 ◽  
Vol 30 (5) ◽  
pp. 898-903 ◽  
Author(s):  
Yan Zhang ◽  
Wan-Ping Lai ◽  
Ping-Chung Leung ◽  
Chun-Fu Wu ◽  
Man-Sau Wong
Keyword(s):  
Bone Mass ◽  
Bone Turnover ◽  
Bone Strength

scholarly journals How can bone turnover modify bone strength independent of bone mass?

Bone ◽  
2008 ◽  
Vol 42 (6) ◽  
pp. 1014-1020 ◽  
Author(s):  
C.J. Hernandez
Keyword(s):  
Bone Mass ◽  
Bone Turnover ◽  
Bone Strength

Calcium homeostasis, bone turnover and bone mass in androgen resistant (testicular feminized) male rats

1992 ◽  
Vol 17 ◽  
pp. 166
Author(s):  
D. Vanderschueren ◽  
E. Van Herck ◽  
I. Jans ◽  
K.W. Chung ◽  
R. Bouillon
Keyword(s):  
Bone Mass ◽  
Bone Turnover ◽  
Calcium Homeostasis ◽  
Male Rats
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