scholarly journals Downturn in Childhood Bone Mass ‐ A Cross‐Sectional Study Over Four Decades

JBMR Plus ◽  
2021 ◽  
Author(s):  
Björn E. Rosengren ◽  
Erika Bergman ◽  
Jessica Karlsson ◽  
Henrik Ahlborg ◽  
Lars Jehpsson ◽  
...  
2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
M. Intriago ◽  
G. Maldonado ◽  
R. Guerrero ◽  
O. D. Messina ◽  
C. Rios

Introduction. An intimate relationship between osteoporosis and sarcopenia has been established. At present, there are few epidemiological studies about osteosarcopenia due to the recent use of this term, especially in Latin America. Objective. To study the association between osteoporosis and sarcopenia and determine the prevalence of osteosarcopenia in patients who attended a rheumatology center in Ecuador. Methods. A cross-sectional study was conducted in a population of patients who had a densitometric study. The diagnosis of sarcopenia was determined by the DXA standard gold test, screening, and conventional methods (bioimpedance, anthropometric measurements, SARC-F, muscle function, and gait test). Results. A total of 92 patients were studied. The median age was 66 ± 10, 90% females. Using the criteria of SMI, 65% had sarcopenia of which 9% had only sarcopenia and 56% had osteosarcopenia; 22% had only osteopenia/osteoporosis; and 13% none of these conditions. The prevalence of sarcopenia according to handgrip strength was 60%, gait speed 45%, and SARC-F score 40%. The prevalence of osteosarcopenia according to handgrip strength was 51%, gait speed 34%, and SARC-F score 32%. Osteoporosis was associated with a higher prevalence of sarcopenia using the criteria of SMI since 40% had sarcopenia in the normal DXA group, 64% in the osteopenia group, and 76% in the osteoporosis group (p=0.017). Of the women, 69% had sarcopenia compared to 33% of the men (p=0.034). The BMI was lower in the group with sarcopenia (25.1 ± 4.1 kg/m2) compared to the group without sarcopenia (29.4 ± 4.1 kg/m2, p<0.001). Patients with osteosarcopenia and sarcopenia had lower BMI, handgrip strength, ASM, SMI, and total-body skeletal muscle mass than those with osteopenia/osteoporosis or normal patients. Conclusion. 65% of the studied population had sarcopenia. It is clear that the prevalence of sarcopenia is higher in patients with greater loss of bone mass. Identifying pathways that affect both bone and muscle could facilitate the development of treatments that simultaneously improve osteoporosis and sarcopenia.


Maturitas ◽  
2013 ◽  
Vol 74 (1) ◽  
pp. 44-53 ◽  
Author(s):  
Alba Gómez-Cabello ◽  
Ignacio Ara ◽  
Alejandro González-Agüero ◽  
José Antonio Casajús ◽  
Germán Vicente-Rodríguez

Bone ◽  
2021 ◽  
pp. 116217
Author(s):  
Ulysses Fagundes ◽  
Rodrigo Luiz Vancini ◽  
Aldo Seffrin ◽  
Alexandre Aparecido de Almeida ◽  
Pantelis T. Nikolaidis ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-6 ◽  
Author(s):  
Nermeen Hijazi ◽  
Zaynab Alourfi

Background. Osteoporosis and hypertension are frequent and often coexisting diseases among the elderly. Recent studies suggested that both diseases may share the same etiopathology. Moreover, the treatment of hypertension can affect the bone mineral density and worsen osteoporosis. The aim of this cross-sectional study was to assess the prevalence of low bone mass and osteoporosis in postmenopausal Syrian women and investigate their relationship with hypertension and antihypertensive drugs. Methods. 813 postmenopausal women were involved in this cross-sectional study, aged between 40 and 96 yrs. Their menopause duration ranged between 1 and 43 yrs. Bone mineral density was measured using a dual-energy X-ray absorptiometry at the total lumbar spine (L1-L4) and left hip. T-score values were used to determine the diagnosis of osteoporosis. The existence of HTN was defined as blood pressure ≥130/85 mmHg or a history of hypertension medication. Results. Using the world health organization criteria, 24% had osteoporosis and 45.2% had low bone mass. The incidence of osteoporosis and low bone mass significantly increased with age and menopause duration and decreased with BMI. Prevalence of hypertension was almost equal among the women who had or did not have osteoporosis. However, hypertensive women who used thiazides or beta blockers had higher values of total lumbar BMD compared with the women who did not. Conclusion. Hypertension in postmenopausal Syrian women aged over 40 was not found to be associated with osteoporosis. However, the mean total lumbar BMD of the hypertensive women who took thiazide diuretics or beta blocker was found to be increased significantly comparing to the women who did not take either.


2002 ◽  
Vol 3 (1) ◽  
Author(s):  
Yuichirou Yahata ◽  
Kiyoshi Aoyagi ◽  
Shoji Yoshida ◽  
Philip D Ross ◽  
Itsuro Yoshimi ◽  
...  

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