scholarly journals Compromised Activation of Vitamin D After Elective Surgery: A Prospective Pilot Study

JBMR Plus ◽  
2018 ◽  
Vol 2 (5) ◽  
pp. 281-288 ◽  
Author(s):  
Martin Blomberg Jensen ◽  
Henrik Husted ◽  
Poul Jannik Bjerrum ◽  
Anders Juul ◽  
Henrik Kehlet
2014 ◽  
Vol 01 (03) ◽  
pp. 198-203 ◽  
Author(s):  
Nidhi Panda ◽  
Preethy Mathew ◽  
Y. Narayana ◽  
Aadarsh Kohli ◽  
Komal Gandhi ◽  
...  

AbstractBackground: Nowadays, hypertension is prevalent in middle aged persons. Patients with hypertension are known to have cognitive dysfunction and, therefore, may be vulnerable for post-operative cognitive dysfunction (POCD) also. Intra-operative hypotension is documented to be associated with cognitive decline in hypertensive patients. Materials and Methods: A prospective pilot study was conducted in 30 hypertensive (Group H) and 30 non-hypertensive (Group N) patients, aged 40-59 years, undergoing elective surgery under general anaesthesia to estimate the incidence of early POCD in known hypertensive patients and compared with non-hypertensive patients. All patients underwent a “Neuro-psychological Test Battery” to assess cognitive function on preoperative day and on 7th postoperative day. A standard anaesthesia protocol was followed. Vasopressor boluses were used to maintain mean arterial pressure (MAP) within 20% of the baseline value in both groups. Results: The incidence of POCD was 23.3% in hypertensive patients and 20% in non-hypertensive patients. The vasopressor boluses used to maintain blood pressure was more in hypertensive patients (P = 0.041). Consequently, hypertensive patients had a significantly higher minimal MAP (P = 0.001) and a lower fractional minimal MAP (P = 0.011) compared to non-hypertensive patients. No significant correlation was observed between fractional minimal MAP and occurrence of POCD. Conclusion: This pilot trial shows that the incidence of early POCD in middle aged hypertensive and non-hypertensive patients are similar after general anaesthesia.


2016 ◽  
Vol 3 (1-2) ◽  
pp. 82-88
Author(s):  
Carmen Elena Gutierrez ◽  
Helga Codina ◽  
Cesar Benjamin Matamoros Pinel ◽  
Edin Hidalgo ◽  
Arturo Arellano ◽  
...  

2013 ◽  
Author(s):  
Babinska-Malec Edyta ◽  
Konstantynowicz Jerzy ◽  
Abramowicz Pawel ◽  
Werpachowska Irena ◽  
Bazyluk-Muszynska Malgorzata ◽  
...  

2018 ◽  
Author(s):  
Angelos Kyriacou ◽  
Alexis Kyriacou ◽  
Akheel A Syed ◽  
Petros Perros

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