The optimization of sintering treatment on bovine‐derived bone grafts for bone regeneration: in vitro and in vivo evaluation

2019 ◽  
Vol 108 (1) ◽  
pp. 272-281 ◽  
Author(s):  
An‐Tian Xu ◽  
Wen‐Ting Qi ◽  
Meng‐Na Lin ◽  
Yu‐Hao Zhu ◽  
Fu‐Ming He
Keyword(s):  
Bone Regeneration ◽  
Bone Grafts ◽  
In Vivo Evaluation ◽  
Regeneration In Vitro

Composite clinoptilolite/PCL‐PEG‐PCL scaffolds for bone regeneration: In vitro and in vivo evaluation

2019 ◽  
Vol 14 (1) ◽  
pp. 3-15 ◽  
Author(s):  
Ahmet Engin Pazarçeviren ◽  
Tayfun Dikmen ◽  
Korhan Altunbaş ◽  
Volkan Yaprakçı ◽  
Özge Erdemli ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
In Vivo Evaluation ◽  
Regeneration In Vitro

scholarly journals Graphene and its Derivatives for Bone Tissue Engineering: In Vitro and In Vivo Evaluation of Graphene-Based Scaffolds, Membranes and Coatings

2021 ◽  
Vol 9 ◽  
Author(s):  
Junyao Cheng ◽  
Jianheng Liu ◽  
Bing Wu ◽  
Zhongyang Liu ◽  
Ming Li ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Regenerative Medicine ◽  
Bone Tissue Engineering ◽  
Bone Regeneration ◽  
Bone Tissue ◽  
Bone Grafts ◽  
Biological Properties ◽  
In Vivo Evaluation

Bone regeneration or replacement has been proved to be one of the most effective methods available for the treatment of bone defects caused by different musculoskeletal disorders. However, the great contradiction between the large demand for clinical therapies and the insufficiency and deficiency of natural bone grafts has led to an urgent need for the development of synthetic bone graft substitutes. Bone tissue engineering has shown great potential in the construction of desired bone grafts, despite the many challenges that remain to be faced before safe and reliable clinical applications can be achieved. Graphene, with outstanding physical, chemical and biological properties, is considered a highly promising material for ideal bone regeneration and has attracted broad attention. In this review, we provide an introduction to the properties of graphene and its derivatives. In addition, based on the analysis of bone regeneration processes, interesting findings of graphene-based materials in bone regenerative medicine are analyzed, with special emphasis on their applications as scaffolds, membranes, and coatings in bone tissue engineering. Finally, the advantages, challenges, and future prospects of their application in bone regenerative medicine are discussed.

scholarly journals In Vitro and In Vivo Evaluation of a Three-Dimensional Porous Multi-Walled Carbon Nanotube Scaffold for Bone Regeneration

Nanomaterials ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 46 ◽  
Author(s):  
Manabu Tanaka ◽  
Yoshinori Sato ◽  
Mei Zhang ◽  
Hisao Haniu ◽  
Masanori Okamoto ◽  
...  
Keyword(s):  
Carbon Nanotube ◽  
Bone Regeneration ◽  
Three Dimensional ◽  
In Vivo Evaluation ◽  
Multi Walled Carbon Nanotube

In Vitro and In Vivo Evaluation of a nHA/PA66 Composite Membrane for Guided Bone Regeneration

2011 ◽  
Vol 22 (1-3) ◽  
pp. 263-275 ◽  
Author(s):  
Jidong Li ◽  
Yi Man ◽  
Yi Zuo ◽  
Li Zhang ◽  
Cui Huang ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Composite Membrane ◽  
Guided Bone Regeneration ◽  
In Vivo Evaluation

scholarly journals In Vitro Physico-Chemical Characterization and Standardized In Vivo Evaluation of Biocompatibility of a New Synthetic Membrane for Guided Bone Regeneration

Materials ◽  
2019 ◽  
Vol 12 (7) ◽  
pp. 1186
Author(s):  
Lívia da Costa Pereira ◽  
Carlos Fernando de Almeida Barros Mourão ◽  
Adriana Terezinha Neves Novellino Alves ◽  
Rodrigo Figueiredo de Brito Resende ◽  
Marcelo José Pinheiro Guedes de Uzeda ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Chemical Properties ◽  
Chemical Characterization ◽  
Guided Bone Regeneration ◽  
Tissue Reaction ◽  
In Vivo Evaluation ◽  
Physico Chemical ◽  
Tissue Reactions

This study’s aim was to evaluate the biocompatibility and bioabsorption of a new membrane for guided bone regeneration (polylactic-co-glycolic acid associated with hydroxyapatite and β-tricalcium phosphate) with three thicknesses (200, 500, and 700 µm) implanted in mice subcutaneously. Scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and the quantification of carbon, hydrogen and nitrogen were used to characterize the physico-chemical properties. One hundred Balb-C mice were divided into 5 experimental groups: Group 1—Sham (without implantation); Group 2—200 μm; Group 3—500 μm; Group 4—700 μm; and Group 5—Pratix®. Each group was subdivided into four experimental periods (7, 30, 60 and 90 days). Samples were collected and processed for histological and histomorphometrical evaluation. The membranes showed no moderate or severe tissue reactions during the experimental periods studied. The 500-μm membrane showed no tissue reaction during any experimental period. The 200-μm membrane began to exhibit fragmentation after 30 days, while the 500-μm and 700-µm membranes began fragmentation at 90 days. All membranes studied were biocompatible and the 500 µm membrane showed the best results for absorption and tissue reaction, indicating its potential for clinical guided bone regeneration.

In vitro and in vivo evaluation of e-PTFE and alkali-cellulose membranes for guided bone regeneration

2001 ◽  
Vol 12 (1) ◽  
pp. 62-68 ◽  
Author(s):  
Luiz A. Salata ◽  
Paul V. Hatton ◽  
A. Jane Devlin ◽  
Geoffrey T. Craig ◽  
Ian M. Brook
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
In Vivo Evaluation ◽  
Alkali Cellulose ◽  
Cellulose Membranes

scholarly journals In vitro and in vivo evaluation of synthetic resorbable membrane for guided bone regeneration

2019 ◽  
Author(s):  
Yusuke Sakaguchi ◽  
Kyohei Toyonaga ◽  
Yuuhiro Sakai ◽  
Emiko Arima ◽  
Shinichi Kato ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
In Vivo Evaluation
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