Preparation and characterization of injectable PMMA‐strontium‐substituted bioactive glass bone cement composites

2017 ◽  
Vol 106 (3) ◽  
pp. 1245-1257 ◽  
Author(s):  
I. Goñi ◽  
R. Rodríguez ◽  
I. García‐Arnáez ◽  
J. Parra ◽  
M. Gurruchaga
Keyword(s):  
Bioactive Glass ◽  
Bone Cement ◽  
Cement Composites

scholarly journals Antibiotic Elution and Mechanical Strength of PMMA Bone Cement Loaded With Borate Bioactive Glass

2018 ◽  
Vol 3 (4) ◽  
pp. 187-196 ◽  
Author(s):  
Grahmm A. Funk ◽  
Jonathan C. Burkes ◽  
Kimberly A. Cole ◽  
Mohamed N. Rahaman ◽  
Terence E. McIff
Keyword(s):  
Mechanical Strength ◽  
Bioactive Glass ◽  
Bone Cement ◽  
Weight Bearing ◽  
Cement Composites ◽  
Delivery Vehicle ◽  
Glass Composites ◽  
Pmma Bone Cement ◽  
Borate Bioactive Glass ◽  
Do So

Abstract. Introduction: Local delivery of antibiotics using bone cement as the delivery vehicle is an established method of managing implant-associated orthopedic infections. Various fillers have been added to cement to increase antibiotic elution, but they often do so at the expense of strength. This study evaluated the effect of adding a borate bioactive glass, previously shown to promote bone formation, on vancomycin elution from PMMA bone cement.Methods: Five cement composites were made: three loaded with borate bioactive glass along with 0, 1, and 5 grams of vancomycin and two without any glass but with 1 and 5 grams vancomycin to serve as controls. The specimens were soaked in PBS. Eluate of vancomycin was collected every 24 hours and analyzed by HPLC. Orthopedic-relevant mechanical properties of each composite were tested over time.Results: The addition of borate bioactive glass provided an increase in vancomycin release at Day 1 and an increase in sustained vancomycin release throughout the treatment period. An 87.6% and 21.1% increase in cumulative vancomycin release was seen for both 1g and 5g loading groups, respectively. Compressive strength of all composites remained above the weight-bearing threshold of 70 MPa throughout the duration of the study with the glass-containing composites showing comparable strength to their respective controls.Conclusion: The incorporation of borate bioactive glass into commercial PMMA bone cement can significantly increase the elution of vancomycin. The mechanical strength of the cement-glass composites remained above 70 MPa even after soaking for 8 weeks, suggesting their suitability for orthopedic weight-bearing applications.

New bioactive glass-ceramic: Synthesis and application in PMMA bone cement composites

2011 ◽  
Vol 21 (4) ◽  
pp. 247-258 ◽  
Author(s):  
Hamizah Abd Samad ◽  
Mariatti Jaafar ◽  
Radzali Othman ◽  
Masakazu Kawashita ◽  
Noor Hayati Abdul Razak
Keyword(s):  
Bioactive Glass ◽  
Bone Cement ◽  
Glass Ceramic ◽  
Cement Composites ◽  
Ceramic Synthesis ◽  
Pmma Bone Cement

Synthesis and characterization of electrospun bioactive glass nanofibers-reinforced calcium sulfate bone cement and its cell biological response

2020 ◽  
Vol 46 (8) ◽  
pp. 10029-10039 ◽  
Author(s):  
Mehdi Shams ◽  
Nader Nezafati ◽  
Delaram Poormoghadam ◽  
Siamak Zavareh ◽  
Ali Zamanian ◽  
...  
Keyword(s):  
Bioactive Glass ◽  
Bone Cement ◽  
Calcium Sulfate ◽  
Biological Response ◽  
Synthesis And Characterization

Synthesis and Characterization of Diethyl Fumarate‐1,4‐Cyclohexanedimethanol Polyesters for Use in Bioresorbable Bone Cement Composites

2006 ◽  
Vol 43 (3) ◽  
pp. 459-467 ◽  
Author(s):  
Gregory B. Kharas ◽  
Anthony Scola ◽  
Kristen Mc Colough ◽  
Allison Crawford ◽  
Celeste A. Diener ◽  
...  
Keyword(s):  
Bone Cement ◽  
Synthesis And Characterization ◽  
Cement Composites

Characterization of the conversion of bone cement and borate bioactive glass composites

2020 ◽  
Vol 108 (4) ◽  
pp. 1580-1591
Author(s):  
Kimberly A. Cole ◽  
Grahmm A. Funk ◽  
Mohamed N. Rahaman ◽  
Terence E. McIff
Keyword(s):  
Bioactive Glass ◽  
Bone Cement ◽  
Glass Composites ◽  
Borate Bioactive Glass

Synthesis and characterization of fumarate-based polyesters for use in bioresorbable bone cement composites

1997 ◽  
Vol 66 (6) ◽  
pp. 1123-1137 ◽  
Author(s):  
Gregory B. Kharas ◽  
Marina Kamenetsky ◽  
James Simantirakis ◽  
Kimberly C. Beinlich ◽  
Ann-Marie T. Rizzo ◽  
...  
Keyword(s):  
Bone Cement ◽  
Synthesis And Characterization ◽  
Cement Composites

scholarly journals Development and characterization of an experimental ZnO cement containing niobophosphate bioactive glass as filling temporary material

2021 ◽  
Author(s):  
Paulo Vitor Campos Ferreira ◽  
Gabriel Flores Abuna ◽  
Bárbara Emanoele Costa Oliveira ◽  
Simonides Consani ◽  
Mário Sinhoreti ◽  
...  
Keyword(s):  
Bioactive Glass
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