scholarly journals The biological response to orthopaedic implants for joint replacement: Part I: Metals

2016 ◽  
Vol 105 (7) ◽  
pp. 2162-2173 ◽  
Author(s):  
Emmanuel Gibon ◽  
Derek F. Amanatullah ◽  
Florence Loi ◽  
Jukka Pajarinen ◽  
Akira Nabeshima ◽  
...  
Author(s):  
M A McGee ◽  
D W Howie ◽  
S D Neale ◽  
D R Haynes ◽  
M J Pearcy

Aseptic loosening is the major cause of failure of joint replacement prostheses. Polyethylene implants removed at revision surgery regularly show wear. It is proposed that the polyethylene particles released into the tissues as a consequence of this wear induce a tissue response that precedes aseptic loosening. This paper presents the results of recent in vivo and in vitro studies of the biological response to polyethylene wear particles undertaken in the authors' laboratories. A clinical perspective is provided by the inclusion of the authors' recent observations of retrieval analyses of joint replacement implant wear and the tissue response to polyethylene in humans.


ASHA Leader ◽  
2016 ◽  
Vol 21 (2) ◽  
pp. 30-31
Author(s):  
Daneen Grooms
Keyword(s):  

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