scholarly journals The biological response to orthopedic implants for joint replacement. II: Polyethylene, ceramics, PMMA, and the foreign body reaction

2016 ◽  
Vol 105 (6) ◽  
pp. 1685-1691 ◽  
Author(s):  
Emmanuel Gibon ◽  
Luis A. Córdova ◽  
Laura Lu ◽  
Tzu-Hua Lin ◽  
Zhenyu Yao ◽  
...  
Keyword(s):  
Foreign Body ◽  
Joint Replacement ◽  
Foreign Body Reaction ◽  
Biological Response ◽  
Orthopedic Implants

scholarly journals Reducing the Foreign Body Reaction by Surface Modification with Collagen/Hyaluronic Acid Multilayered Films

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Cindy Yi Chi Hsieh ◽  
Fang-Wei Hu ◽  
Wen-Shiang Chen ◽  
Wei-Bor Tsai
Keyword(s):  
Surface Modification ◽  
Hyaluronic Acid ◽  
Foreign Body ◽  
Type I Collagen ◽  
Foreign Body Reaction ◽  
Biological Response ◽  
Multilayer Films ◽  
Type I ◽  
Layer By Layer

Biological response against foreign implants often leads to encapsulation, possibly resulting in malfunction of implants devices. The aim of this study was to reduce the foreign body reaction by surface modification of biomaterials through layer-by-layer deposition of type I collagen (COL)/hyaluronic acid (HA) multilayer films. Polydimethylsiloxane (PDMS) samples were coated with alternative COL and HA layers with different layers. We found that the in vitro adhesion, proliferation, and activation of macrophage-like cells were greatly decreased by COL/HA multilayered deposition. The PDMS samples modified with 20 bilayers of COL/HA were implanted in rats for 3 weeks, and the thickness of encapsulation surrounding the samples was decreased by 29–57% compared to the control unmodified PDMS. This study demonstrates the potential of COL/HA multilayer films to reduce foreign body reaction.

scholarly journals Granuloma Caused by Carbon Deposition in the Dermis

2014 ◽  
Vol 2014 ◽  
pp. 1-2
Author(s):  
Rintaro Shibuya ◽  
Yuichiro Endo ◽  
Akihiro Fujisawa ◽  
Miki Tanioka ◽  
Yoshiki Miyachi
Keyword(s):  
Computed Tomography ◽  
Foreign Body ◽  
Malignant Melanoma ◽  
Soft Tissue ◽  
Soft Tissue Sarcoma ◽  
Foreign Body Reaction ◽  
Carbon Deposition ◽  
Case Reports ◽  
Initial Injury ◽  
Pencil Lead

Pencil core granuloma is characterized by a delayed foreign-body reaction against retained fragments of pencil lead. Previous case reports presented pencil core granuloma resembling malignant melanoma, haemangioma, or soft tissue sarcoma. We present a case of pencil core granuloma arising from the palm 25 years after the initial injury. The patient presented a bluish nodule that had been present over 25 years before. The nodule initially measured 5 mm in diameter. However, five years before presentation, it suddenly enlarged to the size of 30 mm during six months. Computed tomography (CT) of the lesion revealed a linear radiopaque structure of 8 mm long with a mass on its distal end. Surgical resection revealed a bluish muddy mass and pencil lead. Histological examination revealed degenerative tissue with calcification surrounded by massive amounts of black granular material in the middle and lower dermis.

Foreign body reaction after cochlear implantation

2011 ◽  
Vol 75 (11) ◽  
pp. 1455-1458 ◽  
Author(s):  
Hye Jin Lim ◽  
Eun-So Lee ◽  
Hun Yi Park ◽  
Keehyun Park ◽  
Yun-Hoon Choung
Keyword(s):  
Foreign Body ◽  
Cochlear Implantation ◽  
Foreign Body Reaction

Foreign body reaction of the brain: Enzyme-histochemical study in dogs

Neurology ◽  
1967 ◽  
Vol 17 (4) ◽  
pp. 337-337 ◽  
Author(s):  
T. Yanagihara ◽  
N. P. Goldstein ◽  
H. J. Svien ◽  
R. C. Bahn
Keyword(s):  
Foreign Body ◽  
Foreign Body Reaction ◽  
Histochemical Study ◽  
The Brain

scholarly journals Delayed Foreign Body Reaction Caused by Bioabsorbable Plates Used for Maxillofacial Fractures

2016 ◽  
Vol 43 (1) ◽  
pp. 40-45 ◽  
Author(s):  
Hong Bae Jeon ◽  
Dong Hee Kang ◽  
Ja Hea Gu ◽  
Sang Ah Oh
Keyword(s):  
Foreign Body ◽  
Foreign Body Reaction ◽  
Maxillofacial Fractures

scholarly journals Foreign Body Reaction Associated With Artificial LARS Ligaments: A Retrieval Study

2018 ◽  
Vol 6 (12) ◽  
pp. 232596711881160 ◽  
Author(s):  
Zachary Paul Sinagra ◽  
Alan Kop ◽  
Moreica Pabbruwe ◽  
Jeremy Parry ◽  
Gavin Clark
Keyword(s):  
Foreign Body ◽  
Foreign Body Reaction ◽  
Fibrous Tissue ◽  
Case Series ◽  
Significant Degree ◽  
Level Of Evidence ◽  
Tissue Ingrowth ◽  
Artificial Ligaments ◽  
Clinically Significant ◽  
Improved Design

Background: Artificial ligaments have been developed and used in the treatment of ligamentous injuries since the 1970s. The early generation of artificial ligaments showed promising short-term results but resulted in high rates of rupture and inflammatory reaction in the surrounding tissues. Purpose: To determine whether the use of Ligament Augmentation and Reconstruction System (LARS) ligaments is associated with the development of intra-articular foreign body reaction. Study Design: Case series; Level of evidence, 4. Methods: LARS ligaments were explanted from 15 patients under 6 consultant orthopaedic surgeons at 8 surgical centers. Of these, 14 explanted samples were sent for macroscopic and histological analysis, with the 1 remaining sample sent for scanning electron microscopy, to assess for inflammatory change as well as the degree of fibrous tissue ingrowth. Results: We observed a foreign body reaction in 10 of 14 explanted LARS ligaments. Seven samples demonstrated fibrous tissue ingrowth, with 5 producing only focal or incomplete ingrowth. The 2 samples with extensive fibrous coverage were completely free of any foreign body reaction, while all 5 remaining samples with only focal or partial fibrous ingrowth were associated with at least some degree of harmful immune response. Conclusion: The LARS ligament is still associated with a clinically significant degree of foreign body reaction despite the LARS Company’s efforts to reduce complications through improved design. The development and completion of fibrous tissue ingrowth may work to reduce the occurrence of a foreign body reaction.

Sign in / Sign up

Export Citation Format

Share Document