Polyester fibers can be rendered calcium phosphate-binding by surface functionalization with bisphosphonate groups

2017 ◽  
Vol 105 (8) ◽  
pp. 2335-2342 ◽  
Author(s):  
Alessandro Polini ◽  
Daniela Geta Petre ◽  
Michele Iafisco ◽  
Sonia de Lacerda Schickert ◽  
Anna Tampieri ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Surface Functionalization ◽  
Phosphate Binding ◽  
Polyester Fibers

scholarly journals Laser-assisted wet coating of calcium phosphate for surface-functionalization of PEEK

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0206524 ◽  
Author(s):  
Ayako Oyane ◽  
Maki Nakamura ◽  
Ikuko Sakamaki ◽  
Yoshiki Shimizu ◽  
Saori Miyata ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Surface Functionalization

Surface functionalization of cuttlefish bone-derived biphasic calcium phosphate scaffolds with polymeric coatings

2019 ◽  
Vol 105 ◽  
pp. 110014 ◽  
Author(s):  
Ana S. Neto ◽  
Ana C. Fonseca ◽  
J.C.C. Abrantes ◽  
Jorge F.J. Coelho ◽  
José M.F. Ferreira
Keyword(s):  
Calcium Phosphate ◽  
Surface Functionalization ◽  
Biphasic Calcium Phosphate ◽  
Polymeric Coatings

Synthesis of calcium phosphate-binding liposome for drug delivery

2009 ◽  
Vol 19 (15) ◽  
pp. 4148-4150 ◽  
Author(s):  
Takahisa Anada ◽  
Yoichi Takeda ◽  
Yoshitomo Honda ◽  
Kazuo Sakurai ◽  
Osamu Suzuki
Keyword(s):  
Drug Delivery ◽  
Calcium Phosphate ◽  
Phosphate Binding

scholarly journals Protein-Bound Calcium Phosphate in Uremic Rat Serum: A Quantitative Study

2020 ◽  
Author(s):  
Hong-Xing Fan ◽  
Bao-Di Gou ◽  
Yu-Xi Gao ◽  
Gang Wu ◽  
Shu-Hu Liu ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Calcium Phosphate ◽  
Kidney Disease ◽  
Serum Proteins ◽  
Chemical Interaction ◽  
Molar Ratio ◽  
Phosphate Binding ◽  
Rat Serum ◽  
Discrete State ◽  
Edge Structure

Protein-bound calcium (prCa) constitutes about 40% of serum total calcium, in which albumin is the most dominant protein. Given the chemical interaction between calcium and phosphate (Pi), the increased serum Pi in chronic kidney disease may cause changes in the composition and structure of the prCa fraction. Here, we report <a>the phosphate binding on the protein-bound calcium in uremic rat serum.</a> Using adenine-fed rats as a uremic model, we determined the levels of calcium and phosphate fractions in rat serum by ultrafiltration, and found that the level of protein-bound phosphate (prPi) in the uremic serum was markedly higher than in control. The elevated prPi level was comparable to the prCa level, consistent with the presence of <a>protein-bound calcium phosphate</a> pr(Ca)<sub>j-m</sub>(CaPi)<sub>m</sub>. We then confirmed its presence by ex vivo X-ray absorption near-edge structure spectroscopy, revealing the discrete state of the calcium phosphate clusters associated with protein. Finally, in a quantitative investigation using Ca- and Pi-boosted serum, we discovered the threshold concentration for the Pi binding on prCa, and determined the binding constant. The threshold, while preventing Pi from binding to prCa in normal condition, allows excess Pi to do so. The protein-bound calcium phosphate could act as a link between the metabolism of serum proteins and the homeostasis of phosphate and calcium, and it deserves further investigation whether the molar ratio of (prPi/prCa)×100% may serve as a serum index of the vascular calcification status in chronic kidney disease.

scholarly journals Biological nano-functionalization of titanium-based biomaterial surfaces: a flexible toolbox

2009 ◽  
Vol 7 (suppl_1) ◽  
Author(s):  
René Beutner ◽  
Jan Michael ◽  
Bernd Schwenzer ◽  
Dieter Scharnweber
Keyword(s):  
Calcium Phosphate ◽  
Titanium Oxide ◽  
Surface Functionalization ◽  
Bioactive Molecules ◽  
Main Field ◽  
Vast Number ◽  
Anodic Titanium Oxide ◽  
Biomaterial Surfaces

Surface functionalization with bioactive molecules (BAMs) on a nanometre scale is a main field in current biomaterial research. The immobilization of a vast number of substances and molecules, ranging from inorganic calcium phosphate phases up to peptides and proteins, has been investigated throughout recent decades. However, in vitro and in vivo results are heterogeneous. This may be at least partially attributed to the limits of the applied immobilization methods. Therefore, this paper highlights, in the first part, advantages and limits of the currently applied methods for the biological nano-functionalization of titanium-based biomaterial surfaces. The second part describes a new immobilization system recently developed in our groups. It uses the nanomechanical fixation of at least partially single-stranded nucleic acids (NAs) into an anodic titanium oxide layer as an immobilization principle and their hybridization ability for the functionalization of the surface with BAMs conjugated to the respective complementary NA strands.

Calcium Phosphate Coating on a Bioresorbable Hydroxyapatite/Collagen Nanocomposite for Surface Functionalization

2013 ◽  
Vol 42 (9) ◽  
pp. 1029-1031 ◽  
Author(s):  
Subhadip Bodhak ◽  
Masanori Kikuchi ◽  
Yu Sogo ◽  
Hideo Tsurushima ◽  
Atsuo Ito ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Surface Functionalization ◽  
Calcium Phosphate Coating ◽  
Phosphate Coating

Investigation of uranium interactions with calcium phosphate-binding proteins using ICP/MS and CE-ICP/MS

Metallomics ◽  
2016 ◽  
Vol 8 (11) ◽  
pp. 1185-1192 ◽  
Author(s):  
Thi-Ngoc Suong Huynh ◽  
Claude Vidaud ◽  
Agnès Hagège
Keyword(s):  
Calcium Phosphate ◽  
Binding Proteins ◽  
Phosphate Binding ◽  
Icp Ms
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