Layer-by-layer coating of textile with two oppositely charged cyclodextrin polyelectrolytes for extended drug delivery

2016 ◽  
Vol 104 (6) ◽  
pp. 1408-1424 ◽  
Author(s):  
Jatupol Junthip ◽  
Nicolas Tabary ◽  
Feng Chai ◽  
Laurent Leclercq ◽  
Mickael Maton ◽  
...  
2006 ◽  
Vol 116 (2) ◽  
pp. 159-169 ◽  
Author(s):  
B.G. De Geest ◽  
C. Déjugnat ◽  
E. Verhoeven ◽  
G.B. Sukhorukov ◽  
A.M. Jonas ◽  
...  

Membranes ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 145
Author(s):  
Kseniia Tsygurina ◽  
Olesya Rybalkina ◽  
Konstantin Sabbatovskiy ◽  
Evgeniy Kirichenko ◽  
Vladimir Sobolev ◽  
...  

Ion exchange membranes covered with layers of polyelectrolytes of alternating charges are characterized by very high monovalent selectivity. This allows the use of such membranes for electrodialytic fractionation of multicomponent solutions. However, the very existence of the boundary at which differently charged layers come in contact can hinder a membrane’s effectiveness by limiting its ion permeability, raising levels of H+ and OH− ions (thus shifting the pH) and increasing the electrical resistance of the membrane, which leads to increased energy consumption. To test how these properties would be changed, we created cheap layer-by-layer-modified membranes based on the heterogeneous MK-40 membrane, on which we adsorbed layers of polyallylamine and sulfonated polystyrene. We created samples with 3, 4, and 5 layers of polyelectrolytes and characterized them. We showed that the application of layers did not decrease the efficiency of the membrane, since the electrical resistance of the modified samples, which increased after application of the first oppositely charged layer, declined with the application of the following layers and became comparable to that of the substrate, while their limiting current density was higher and the shift of pH of treated solution was low in magnitude and comparable with that of the substrate membrane.


2019 ◽  
Vol 488 ◽  
pp. 194-204 ◽  
Author(s):  
Erica D. de Avila ◽  
Antonio G.B. Castro ◽  
Oya Tagit ◽  
Bastiaan P. Krom ◽  
Dennis Löwik ◽  
...  

2020 ◽  
Vol 587 ◽  
pp. 119730
Author(s):  
Jatupol Junthip ◽  
Nicolas Tabary ◽  
Mickael Maton ◽  
Safa Ouerghemmi ◽  
Jean-Noel Staelens ◽  
...  

2021 ◽  
pp. 117604
Author(s):  
Beatriz S. Verza ◽  
Jeroen J.J.P. van den Beucken ◽  
João V. Brandt ◽  
Miguel Jafelicci Junior ◽  
Valentim A.R. Barão ◽  
...  

2015 ◽  
Vol 51 (2) ◽  
pp. 255-263
Author(s):  
Rupali Nanasaheb Kadam ◽  
Raosaheb Sopanrao Shendge ◽  
Vishal Vijay Pande

<p>The use of nanotechnology based on the development and fabrication of nanostructures is one approach that has been employed to overcome the challenges involved with conventional drug delivery systems. Formulating Nanoplex is the new trend in nanotechnology. A nanoplex is a complex formed by a drug nanoparticle with an oppositely charged polyelectrolyte. Both cationic and anionic drugs form complexes with oppositely charged polyelectrolytes. Compared with other nanostructures, the yield of Nanoplex is greater and the complexation efficiency is better. Nanoplex are also easier to prepare. Nanoplex formulation is characterized through the production yield, complexation efficiency, drug loading, particle size and zeta potential using scanning electron microscopy, differential scanning calorimetry, X-ray diffraction and dialysis studies. Nanoplex have wide-ranging applications in different fields such as cancer therapy, gene drug delivery, drug delivery to the brain and protein and peptide drug delivery.</p>


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