The effect of calcium phosphate composite scaffolds on the osteogenic differentiation of rabbit dental pulp stem cells

2014 ◽  
Vol 103 (5) ◽  
pp. 1732-1745 ◽  
Author(s):  
Ling E. Ling ◽  
Lin Feng ◽  
Hong‐Chen Liu ◽  
Dong‐Sheng Wang ◽  
Zhan‐Ping Shi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Calcium Phosphate ◽  
Osteogenic Differentiation ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Composite Scaffolds ◽  
Rabbit Dental Pulp

The effect of composition of calcium phosphate composite scaffolds on the formation of tooth tissue from human dental pulp stem cells

Biomaterials ◽  
2011 ◽  
Vol 32 (29) ◽  
pp. 7053-7059 ◽  
Author(s):  
Liqin Zheng ◽  
Fei Yang ◽  
Hong Shen ◽  
Xuefeng Hu ◽  
Chihiro Mochizuki ◽  
...  
Keyword(s):  
Stem Cells ◽  
Calcium Phosphate ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Composite Scaffolds ◽  
Human Dental Pulp ◽  
Tooth Tissue

scholarly journals Development of novel gene carrier using modified nano hydroxyapatite derived from equine bone for osteogenic differentiation of dental pulp stem cells

2021 ◽  
Vol 6 (9) ◽  
pp. 2742-2751
Author(s):  
Myung Chul Lee ◽  
Hoon Seonwoo ◽  
Kyoung Je Jang ◽  
Shambhavi Pandey ◽  
Jaewoon Lim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Osteogenic Differentiation ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Gene Carrier ◽  
Novel Gene ◽  
Equine Bone

Chrysin induces osteogenic differentiation of human dental pulp stem cells

2021 ◽  
Vol 400 (2) ◽  
pp. 112466
Author(s):  
J.F. Huo ◽  
M.L. Zhang ◽  
X.X. Wang ◽  
D.H. Zou
Keyword(s):  
Stem Cells ◽  
Osteogenic Differentiation ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Human Dental Pulp

scholarly journals Enhanced Osteogenesis of Dental Pulp Stem Cells In Vitro Induced by Chitosan–PEG-Incorporated Calcium Phosphate Cement

Polymers ◽  
2021 ◽  
Vol 13 (14) ◽  
pp. 2252
Author(s):  
Jae Eun Kim ◽  
Sangbae Park ◽  
Woong-Sup Lee ◽  
Jinsub Han ◽  
Jae Woon Lim ◽  
...  
Keyword(s):  
Stem Cells ◽  
Calcium Phosphate ◽  
Zeta Potential ◽  
Mechanical Strength ◽  
Calcium Phosphate Cement ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Ion Trapping ◽  
Alizarin Red

The use of bone graft materials is required for the treatment of bone defects damaged beyond the critical defect; therefore, injectable calcium phosphate cement (CPC) is actively used after surgery. The application of various polymers to improve injectability, mechanical strength, and biological function of injection-type CPC is encouraged. We previously developed a chitosan–PEG conjugate (CS/PEG) by a sulfur (VI) fluoride exchange reaction, and the resulting chitosan derivative showed high solubility at a neutral pH. We have demonstrated the CPC incorporated with a poly (ethylene glycol) (PEG)-grafted chitosan (CS/PEG) and developed CS/PEG CPC. The characterization of CS/PEG CPC was conducted using Fourier transform infrared spectroscopy (FT-IR) and X-ray diffraction (XRD). The initial properties of CS/PEG CPCs, such as the pH, porosity, mechanical strength, zeta potential, and in vitro biocompatibility using the WST-1 assay, were also investigated. Moreover, osteocompatibility of CS/PEG CPCs was carried out via Alizarin Red S staining, immunocytochemistry, and Western blot analysis. CS/PEG CPC has enhanced mechanical strength compared to CPC, and the cohesion test also demonstrated in vivo stability. Furthermore, we determined whether CS/PEG CPC is a suitable candidate for promoting the osteogenic ability of Dental Pulp Stem Cells (DPSC). The elution of CS/PEG CPC entraps more calcium ion than CPC, as confirmed through the zeta potential test. Accordingly, the ion trapping effect of CS/PEG is considered to have played a role in promoting osteogenic differentiation of DPSCs. The results strongly suggested that CS/PEG could be used as suitable additives for improving osteogenic induction of bone substitute materials.

The effect of larger than cell diameter polylactic acid surface patterns on osteogenic differentiation of rat dental pulp stem cells

2018 ◽  
Vol 107 (1) ◽  
pp. 174-186 ◽  
Author(s):  
Milda Alksne ◽  
Egidijus Simoliunas ◽  
Migle Kalvaityte ◽  
Edvinas Skliutas ◽  
Ieva Rinkunaite ◽  
...  
Keyword(s):  
Stem Cells ◽  
Osteogenic Differentiation ◽  
Polylactic Acid ◽  
Dental Pulp ◽  
Dental Pulp Stem Cells ◽  
Cell Diameter ◽  
Surface Patterns
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