Incorporation of growth factor loaded microspheres into polymeric electrospun nanofibers for tissue engineering applications

2013 ◽  
Vol 102 (6) ◽  
pp. 1897-1908 ◽  
Author(s):  
P. Selcan Gungor-Ozkerim ◽  
Timucin Balkan ◽  
Gamze T. Kose ◽  
A. Sezai Sarac ◽  
Fatma N. Kok
Keyword(s):  
Tissue Engineering ◽  
Growth Factor ◽  
Electrospun Nanofibers ◽  
Engineering Applications

scholarly journals A new design of an electrospinning apparatus for tissue engineering applications

2017 ◽  
Vol 3 (2) ◽  
Author(s):  
Juliana R. Dias ◽  
Cyril Dos Santos ◽  
João Horta ◽  
Pedro Lopes Granja ◽  
Paulo Jorge Da Silva Bartolo
Keyword(s):  
Tissue Engineering ◽  
Simple Technique ◽  
Electrospun Nanofibers ◽  
Processing Parameters ◽  
Wound Dressings ◽  
Engineering Applications ◽  
Electrospinning Technique ◽  
Skin Tissue Engineering ◽  
Spinning Process ◽  
The Stability

The electrospinning technique is being widely explored in the biomedical field due to its simplicity to produce meshes and its capacity to mimic the micro-nanostructure of the natural extracellular matrix. For skin tissue engineering applications, wound dressings made from electrospun nanofibers present several advantages compared to conventional dressings, such as the promotion of the hemostasis phase, wound exudate absorption, semi-permeability, easy conformability to the wound, functional ability and no scar induction. Despite being a relatively simple technique, electrospinning is strongly influenced by polymer solution characteristics, processing parameters and environmental conditions, which strongly determine the production of fibers and their morphology. However, most electrospinning systems are wrongly designed, presenting a large number of conductive components that compromises the stability of the spinning process. This paper presents a new design of an electrospinning system solving the abovementioned limitations. The system was assessed through the production of polycaprolactone (PCL) and gelatin nanofibers.  Different solvents and processing parameters were considered. Results show that the proposed electrospinning system is suitable to produce reproducible and homogeneous electrospun fibers for tissue engineering applications.

Design and characterization of biodegradable multi layered electrospun nanofibers for corneal tissue engineering applications

2019 ◽  
Vol 107 (10) ◽  
pp. 2340-2349 ◽  
Author(s):  
Zohreh Arabpour ◽  
Alireza Baradaran‐Rafii ◽  
Nasrin L. Bakhshaiesh ◽  
Jafar Ai ◽  
Somayeh Ebrahimi‐Barough ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Electrospun Nanofibers ◽  
Corneal Tissue ◽  
Engineering Applications
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