Osteoblastic cell response on biphasic fluorhydroxyapatite/strontium-substituted hydroxyapatite coatings

2013 ◽  
Vol 102 (3) ◽  
pp. 621-627 ◽  
Author(s):  
Ping Yin ◽  
Fang Fang Feng ◽  
Ting Lei ◽  
Xiao Huan Zhong ◽  
Xin Chun Jian
Keyword(s):  
Cell Response ◽  
Osteoblastic Cell ◽  
Hydroxyapatite Coatings

Osteoblastic cell response on fluoridated hydroxyapatite coatings: the effect of magnesium incorporation

2010 ◽  
Vol 5 (5) ◽  
pp. 054114 ◽  
Author(s):  
Y L Cai ◽  
J J Zhang ◽  
S Zhang ◽  
S S Venkatraman ◽  
X T Zeng ◽  
...  
Keyword(s):  
Cell Response ◽  
Osteoblastic Cell ◽  
Fluoridated Hydroxyapatite ◽  
Hydroxyapatite Coatings

Osteoblastic cell response on fluoridated hydroxyapatite coatings

2007 ◽  
Vol 3 (2) ◽  
pp. 191-197 ◽  
Author(s):  
Yongsheng Wang ◽  
Sam Zhang ◽  
Xianting Zeng ◽  
Lwin Lwin Ma ◽  
Wenjian Weng ◽  
...  
Keyword(s):  
Cell Response ◽  
Osteoblastic Cell ◽  
Fluoridated Hydroxyapatite ◽  
Hydroxyapatite Coatings

scholarly journals Surface characteristics and osteoblastic cell response of alkali-and heat-treated titanium-8tantalum-3niobium alloy

2012 ◽  
Vol 42 (6) ◽  
pp. 248 ◽  
Author(s):  
Bo-Ah Lee ◽  
Choong-Hee Kang ◽  
Mong-Sook Vang ◽  
Young-Suk Jung ◽  
Xing Hui Piao ◽  
...  
Keyword(s):  
Cell Response ◽  
Surface Characteristics ◽  
Osteoblastic Cell ◽  
Heat Treated

Osteoblastic cell responses and antibacterial efficacy of Cu/Zn co-substituted hydroxyapatite coatings on pure titanium using electrodeposition method

RSC Advances ◽  
2015 ◽  
Vol 5 (22) ◽  
pp. 17076-17086 ◽  
Author(s):  
Yong Huang ◽  
Xuejiao Zhang ◽  
Huanhuan Mao ◽  
Tingting Li ◽  
Ranlin Zhao ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Dental Implant ◽  
Pure Titanium ◽  
Osteoblastic Cell ◽  
Antibacterial Efficacy ◽  
Electrodeposition Method ◽  
Cell Responses ◽  
Hydroxyapatite Coatings ◽  
Bone Integration

Effective physiological bone integration and absence of bacterial infection are essential for a successful orthopaedic or dental implant.

scholarly journals Human foetal osteoblastic cell response to polymer-demixed nanotopographic interfaces

2005 ◽  
Vol 2 (2) ◽  
pp. 97-108 ◽  
Author(s):  
Jung Yul Lim ◽  
Joshua C Hansen ◽  
Christopher A Siedlecki ◽  
James Runt ◽  
Henry J Donahue
Keyword(s):  
Cell Response ◽  
Cell Function ◽  
Early Stage ◽  
Control Cell ◽  
Bone Cell ◽  
Cell Phenotype ◽  
Osteoblastic Cell ◽  
Bone Cell Differentiation ◽  
Biomaterial Interfaces ◽  
Cells Cultured

Nanoscale cell–substratum interactions are of significant interest in various biomedical applications. We investigated human foetal osteoblastic cell response to randomly distributed nanoisland topography with varying heights (11, 38 and 85 nm) produced by a polystyrene (PS)/polybromostyrene polymer-demixing technique. Cells displayed island-conforming lamellipodia spreading, and filopodia projections appeared to play a role in sensing the nanotopography. Cells cultured on 11 nm high islands displayed significantly enhanced cell spreading and larger cell dimensions than cells on larger nanoislands or flat PS control, on which cells often displayed a stellate shape. Development of signal transmitting structures such as focal adhesive vinculin protein and cytoskeletal actin stress fibres was more pronounced, as was their colocalization, in cells cultured on smaller nanoisland surfaces. Cell adhesion and proliferation were greater with decreasing island height. Alkaline phosphatase (AP) activity, an early stage marker of bone cell differentiation, also exhibited nanotopography dependence, i.e. higher AP activity on 11 nm islands compared with that on larger islands or flat PS. Therefore, randomly distributed island topography with varying nanoscale heights not only affect adhesion-related cell behaviour but also bone cell phenotype. Our results suggest that modulation of nanoscale topography may be exploited to control cell function at cell–biomaterial interfaces.

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