Osteoblastic cell responses and antibacterial efficacy of Cu/Zn co-substituted hydroxyapatite coatings on pure titanium using electrodeposition method

RSC Advances ◽  
2015 ◽  
Vol 5 (22) ◽  
pp. 17076-17086 ◽  
Author(s):  
Yong Huang ◽  
Xuejiao Zhang ◽  
Huanhuan Mao ◽  
Tingting Li ◽  
Ranlin Zhao ◽  
...  
Keyword(s):  
Bacterial Infection ◽  
Dental Implant ◽  
Pure Titanium ◽  
Osteoblastic Cell ◽  
Antibacterial Efficacy ◽  
Electrodeposition Method ◽  
Cell Responses ◽  
Hydroxyapatite Coatings ◽  
Bone Integration

Effective physiological bone integration and absence of bacterial infection are essential for a successful orthopaedic or dental implant.

DJK-5 incorporated porous titanium alloy with combined superior antibacterial efficacy and enhanced osteoblastic cell responses

2019 ◽  
Vol 251 ◽  
pp. 161-164 ◽  
Author(s):  
Junwei Zhang ◽  
Yao Wang ◽  
Tao Gao ◽  
Nihui Zhang ◽  
Jing He ◽  
...  
Keyword(s):  
Titanium Alloy ◽  
Porous Titanium ◽  
Osteoblastic Cell ◽  
Antibacterial Efficacy ◽  
Cell Responses

Antibiotic-Loaded Chitosan Hydrogel with Superior Dual Functions: Antibacterial Efficacy and Osteoblastic Cell Responses

2014 ◽  
Vol 6 (13) ◽  
pp. 10005-10013 ◽  
Author(s):  
Fang Wu ◽  
Guolong Meng ◽  
Jing He ◽  
Yao Wu ◽  
Fang Wu ◽  
...  
Keyword(s):  
Osteoblastic Cell ◽  
Antibacterial Efficacy ◽  
Chitosan Hydrogel ◽  
Cell Responses ◽  
Dual Functions

scholarly journals Long-lasting renewable antibacterial porous polymeric coatings enable titanium biomaterials to prevent and treat peri-implant infection

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Shuyi Wu ◽  
Jianmeng Xu ◽  
Leiyan Zou ◽  
Shulu Luo ◽  
Run Yao ◽  
...  
Keyword(s):  
Dental Implant ◽  
Pathogenic Bacteria ◽  
Titanium Surface ◽  
Polymeric Coating ◽  
Antibacterial Efficacy ◽  
Polymeric Coatings ◽  
Implant Infection ◽  
Titanium Surfaces

AbstractPeri-implant infection is one of the biggest threats to the success of dental implant. Existing coatings on titanium surfaces exhibit rapid decrease in antibacterial efficacy, which is difficult to promisingly prevent peri-implant infection. Herein, we report an N-halamine polymeric coating on titanium surface that simultaneously has long-lasting renewable antibacterial efficacy with good stability and biocompatibility. Our coating is powerfully biocidal against both main pathogenic bacteria of peri-implant infection and complex bacteria from peri-implantitis patients. More importantly, its antibacterial efficacy can persist for a long term (e.g., 12~16 weeks) in vitro, in animal model, and even in human oral cavity, which generally covers the whole formation process of osseointegrated interface. Furthermore, after consumption, it can regain its antibacterial ability by facile rechlorination, highlighting a valuable concept of renewable antibacterial coating in dental implant. These findings indicate an appealing application prospect for prevention and treatment of peri-implant infection.

Wettability and osteoblastic cell adhesion on ultrapolished commercially pure titanium surfaces: the role of the oxidation and pollution states

2014 ◽  
Vol 28 (12) ◽  
pp. 1207-1218 ◽  
Author(s):  
Miguel A. Fernández-Rodríguez ◽  
Alda Y. Sánchez-Treviño ◽  
Elvira De Luna-Bertos ◽  
Javier Ramos-Torrecillas ◽  
Olga García-Martínez ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Pure Titanium ◽  
Osteoblastic Cell ◽  
Commercially Pure Titanium ◽  
Commercially Pure ◽  
Titanium Surfaces

Bacterial Infection with Listeria monocytogenes in Mice and Subsequent Analysis of AntigenSpecific CD8 T Cell Responses

BIO-PROTOCOL ◽  
2021 ◽  
Vol 11 (23) ◽  
Author(s):  
Bojana Jakic ◽  
Janine Kimpel ◽  
William Olson ◽  
Verena Labi ◽  
Natascha Hermann-Kleiter
Keyword(s):  
Listeria Monocytogenes ◽  
T Cell ◽  
Bacterial Infection ◽  
T Cell Responses ◽  
Cd8 T Cell ◽  
Cell Responses

scholarly journals Lactoferrin Coating Improves the Antibacterial and Osteogenic Properties of Alkali-Treated Titanium with Nanonetwork Structures

2020 ◽  
Vol 2020 ◽  
pp. 1-13
Author(s):  
Derong Yin ◽  
Yonglong Hong ◽  
Luyuan Chen ◽  
Satoshi Komasa ◽  
Yuanyuan Yang ◽  
...  
Keyword(s):  
Dental Implant ◽  
Alkali Treatment ◽  
Pure Titanium ◽  
Antimicrobial Properties ◽  
Biological Properties ◽  
Bacterial Attachment ◽  
Physiological Concentration ◽  
Implant Materials

Titanium and its alloys are the main dental implant materials used at present. The biological properties of pure titanium can be further improved by surface treatment methods. Alkali treatment of pure titanium at room temperature can form nanonetwork structures (TNS) on the surface, which has better osteoinductive ability than pure titanium. However, TNS does not possess antimicrobial properties, and bacterial infection is one of the main reasons for the failure of dental implant therapy. Therefore, it was the focus of our research to endow TNS with certain antimicrobial properties on the premise of maintaining its osteoinductive ability. Because of its excellent broad-spectrum antimicrobial properties and because it promotes osteoblast-like cell growth, lactoferrin (LF) was considered a promising prospect as a surface biological treatment material. In this study, bovine LF of physiological concentration was successfully coated on the surface of TNS to form the TNS-LF composite material. Results from in vitro and in vivo experiments showed that TNS-LF had better osteoinductive ability than TNS. Bacterial attachment and biofilm formation were also significantly decreased on the surface of TNS-LF. Therefore, this study has provided an experimental basis for the development of osteoinduction-antimicrobial composite implant materials for dental applications.

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