scholarly journals Effect of fiber crosslinking on collagen-fiber reinforced collagen-chondroitin-6-sulfate materials for regenerating load-bearing soft tissues

2012 ◽  
Vol 101A (1) ◽  
pp. 176-184 ◽  
Author(s):  
J. H. Shepherd ◽  
S. Ghose ◽  
S. J. Kew ◽  
A. Moavenian ◽  
S. M. Best ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-9
Author(s):  
Yan Chen ◽  
Yuting Yan ◽  
Xiaoming Li ◽  
He Li ◽  
Huiting Tan ◽  
...  

To date, fiber reinforce scaffolds have been largely applied to repair hard and soft tissues. Meanwhile, monitoring the scaffolds for long periodsin vivois recognized as a crucial issue before its wide use. As a consequence, there is a growing need for noninvasive and convenient methods to analyze the implantation remolding processin situand in real time. In this paper, diagnostic medical ultrasound was used to monitor thein vivobone formation and degradation process of the novel mineralized collagen fiber reinforced composite which is synthesized by chitosan (CS), nanohydroxyapatite (nHA), and collagen fiber (Col). To observe the impact of cells on bone remodeling process, the scaffolds were planted into the back of the SD rats with and without rat bone mesenchymal stem cells (rBMSCs). Systematic data of scaffoldsin vivowas extracted from ultrasound images. Significant consistency between the data from the ultrasound and DXA could be observedP<0.05. This indicated that ultrasound may serve as a feasible alternative for noninvasive monitoring the evolution of scaffoldsin situduring cell growth.


2020 ◽  
Vol 143 (1) ◽  
Author(s):  
Madison E. Wale ◽  
Derek Q. Nesbitt ◽  
Bradley S. Henderson ◽  
Clare K. Fitzpatrick ◽  
Jaremy J. Creechley ◽  
...  

Abstract Tensile testing is an essential experiment to assess the mechanical integrity of musculoskeletal soft tissues, yet standard test methods have not been developed to ensure the quality and reproducibility of these experiments. The ASTM International standards organization has created tensile test standards for common industry materials that specify geometric dimensions of test specimens (coupons) that promote valid failures within the gage section (midsubstance), away from the grips. This study examined whether ASTM test standards for plastics, elastomers, and fiber-reinforced composites are suitable for tensile testing of bovine meniscus along the circumferential fiber direction. We found that dumbbell (DB) shaped coupons based on ASTM standards for elastomers and plastics had an 80% and 60% rate of midsubstance failures, respectively. The rate of midsubstance failures dropped to 20% when using straight (ST) coupons based on ASTM standards for fiber-reinforced composites. The mechanical properties of dumbbell shaped coupons were also significantly greater than straight coupons. Finite element models of the test coupons revealed stress distributions that supported our experimental findings. In addition, we found that a commercial deli-slicer was able to slice meniscus to uniform layer thicknesses that were within ASTM dimensional tolerances. This study provides methods, recommendations, and insights that can advance the standardization of tensile testing in meniscus and other soft fibrous tissues.


2020 ◽  
Vol 46 (6) ◽  
pp. 7903-7911
Author(s):  
Xueni Zhao ◽  
Jiamei Zheng ◽  
Weigang Zhang ◽  
Xueyan Chen ◽  
Zhenzhen Gui

Author(s):  
Hussain Alghahtani ◽  
Seyed M. Allameh

Biomimicked composites have shown to be superior to monolithic structural materials. However, they need reinforcement to replace conventional load-bearing structural composites. Carbon Fibers in long and short forms were used as reinforcement in biomimicked composites. Mechanical tests including four point bending were conducted to determine the effects of form and volume fraction of fibers on the fracture toughness of the biomimicked composites.


2010 ◽  
Vol 6 (7) ◽  
pp. 2365-2381 ◽  
Author(s):  
John A. Stella ◽  
Antonio D’Amore ◽  
William R. Wagner ◽  
Michael S. Sacks
Keyword(s):  

2013 ◽  
Vol 689 ◽  
pp. 353-357
Author(s):  
Chong Xi Bai ◽  
Xin Yan Shao ◽  
Qiu Ping Wang

The law of stress increment of unbonded carbon fiber reinforced polymer (CFRP) tendons at service stage and flexural load bearing capacity limit state is unclear, so it is difficult to accurately calculate crack width, deflection and load bearing capacity. In order to calculate the stress of CFRP tendons, deformation compatibility condition and moment-curvature analysis method are used to compile nonlinear full-range analysis programs of simply supported concrete beam partially prestressed with unbonded CFRP tendons. The computing results of stress in CFRP tendons are in good agreement with the tested results as a whole, so it indicates that the simulation analysis programs are reliable.


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