scholarly journals Osteoclastogenesis and osteoclastic resorption of tricalcium phosphate: Effect of strontium and magnesium doping

2012 ◽  
pp. n/a-n/a ◽  
Author(s):  
Mangal Roy ◽  
Susmita Bose
Keyword(s):  
Tricalcium Phosphate ◽  
Magnesium Doping ◽  
Phosphate Effect ◽  
Osteoclastic Resorption

scholarly journals Effect of grain orientation and magnesium doping on β-tricalcium phosphate resorption behavior

2019 ◽  
Vol 89 ◽  
pp. 391-402 ◽  
Author(s):  
Marta Gallo ◽  
Bastien Le Gars Santoni ◽  
Thierry Douillard ◽  
Fei Zhang ◽  
Laurent Gremillard ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Grain Orientation ◽  
Magnesium Doping

scholarly journals Microporosities in 3D-Printed Tricalcium-Phosphate-Based Bone Substitutes Enhance Osteoconduction and Affect Osteoclastic Resorption

2020 ◽  
Vol 21 (23) ◽  
pp. 9270
Author(s):  
Chafik Ghayor ◽  
Tse-Hsiang Chen ◽  
Indranil Bhattacharya ◽  
Mutlu Özcan ◽  
Franz E. Weber
Keyword(s):  
Additive Manufacturing ◽  
Tricalcium Phosphate ◽  
Major Complication ◽  
Bone Substitutes ◽  
In Vivo Studies ◽  
Patient Specific ◽  
Osteoclastic Resorption ◽  
3D Printed ◽  
High Degree

Additive manufacturing is a key technology required to realize the production of a personalized bone substitute that exactly meets a patient’s need and fills a patient-specific bone defect. Additive manufacturing can optimize the inner architecture of the scaffold for osteoconduction, allowing fast and reliable defect bridging by promoting rapid growth of new bone tissue into the scaffold. The role of scaffold microporosity/nanoarchitecture in osteoconduction remains elusive. To elucidate this relationship, we produced lithography-based osteoconductive scaffolds from tricalcium phosphate (TCP) with identical macro- and microarchitecture, but varied their nanoarchitecture/microporosity by ranging maximum sintering temperatures from 1000 °C to 1200 °C. After characterization of the different scaffolds’ microporosity, compression strength, and nanoarchitecture, we performed in vivo studies that showed that ingrowth of bone as an indicator of osteoconduction significantly decreased with decreasing microporosity. Moreover, at the 1200 °C peak sinter temperature and lowest microporosity, osteoclastic degradation of the material was inhibited. Thus, even for wide-open porous TCP-based scaffolds, a high degree of microporosity appears to be essential for optimal osteoconduction and creeping substitution, which can prevent non-unions, the major complication during bone regeneration procedures.

α-Tricalcium phosphate hydrolysis to octacalcium phosphate: effect of sodium polyacrylate

Biomaterials ◽  
2002 ◽  
Vol 23 (8) ◽  
pp. 1849-1854 ◽  
Author(s):  
A. Bigi ◽  
E. Boanini ◽  
R. Botter ◽  
S. Panzavolta ◽  
K. Rubini
Keyword(s):  
Tricalcium Phosphate ◽  
Octacalcium Phosphate ◽  
Sodium Polyacrylate ◽  
Phosphate Effect ◽  
Phosphate Hydrolysis

Effects of alendronate on bone formation and osteoclastic resorption after implantation of beta-tricalcium phosphate

2009 ◽  
Vol 9999A ◽  
pp. NA-NA ◽  
Author(s):  
Takaaki Tanaka ◽  
Mitsuru Saito ◽  
Masaaki Chazono ◽  
Yoshio Kumagae ◽  
Takahiro Kikuchi ◽  
...  
Keyword(s):  
Bone Formation ◽  
Tricalcium Phosphate ◽  
Beta Tricalcium Phosphate ◽  
Osteoclastic Resorption

scholarly journals α-Tricalcium Phosphate Effect on the Properties of Calcium Phosphate Bone Cements

2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Mostafa Shahrezaei ◽  
Jalal Shahrouzi ◽  
Saeed Hesaraki ◽  
Ali Zamanian
Keyword(s):  
Calcium Phosphate ◽  
Tricalcium Phosphate ◽  
Bone Cements ◽  
Phosphate Effect
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