Effects of alendronate on bone formation and osteoclastic resorption after implantation of beta-tricalcium phosphate

2009 ◽  
Vol 9999A ◽  
pp. NA-NA ◽  
Author(s):  
Takaaki Tanaka ◽  
Mitsuru Saito ◽  
Masaaki Chazono ◽  
Yoshio Kumagae ◽  
Takahiro Kikuchi ◽  
...  
Keyword(s):  
Bone Formation ◽  
Tricalcium Phosphate ◽  
Beta Tricalcium Phosphate ◽  
Osteoclastic Resorption

Generation of an rhBMP-2-loaded beta-tricalcium phosphate/hydrogel composite and evaluation of its efficacy on peri-implant bone formation

2014 ◽  
Vol 9 (5) ◽  
pp. 055002 ◽  
Author(s):  
Jae Hyup Lee ◽  
Mi Young Ryu ◽  
Hae-Ri Baek ◽  
Jun-Hyuk Seo ◽  
Kyung-Mee Lee ◽  
...  
Keyword(s):  
Bone Formation ◽  
Tricalcium Phosphate ◽  
Hydrogel Composite ◽  
Beta Tricalcium Phosphate

Effects of teriparatide on bone formation in novel unidirectional porous beta-tricalcium phosphate

2019 ◽  
Vol 34 (5) ◽  
pp. 721-727
Author(s):  
Hiroshi Kumagai ◽  
Toru Funayama ◽  
Hisashi Sugaya ◽  
Tomokazu Yoshioka ◽  
Takeshi Makihara ◽  
...  
Keyword(s):  
Bone Formation ◽  
Tricalcium Phosphate ◽  
Beta Tricalcium Phosphate

Bone formation in a rat calvarial defect model after transplanting autogenous bone marrow with beta-tricalcium phosphate

2010 ◽  
Vol 112 (3) ◽  
pp. 270-277 ◽  
Author(s):  
Nobuaki Shirasu ◽  
Takaaki Ueno ◽  
Yasuhisa Hirata ◽  
Azumi Hirata ◽  
Toshimasa Kagawa ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Formation ◽  
Tricalcium Phosphate ◽  
Autogenous Bone ◽  
Calvarial Defect ◽  
Defect Model ◽  
Beta Tricalcium Phosphate ◽  
Rat Calvarial Defect

scholarly journals Osteopontin and Vascular Endothelial Growth Factor-Immunoreactivity in Critical Bone Defects Matrix Production: A Nano-Hydroxyapatite/Beta-Tricalcium Phosphate and Xenogeneic Hydroxyapatite Comparison

Minerals ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 1048
Author(s):  
Ivonete Sena dos Santos ◽  
Igor da Silva Brum ◽  
Victor Hugo Vieira de Oliveira ◽  
Ana Lucia Rosa Nascimento ◽  
Lucio Frigo ◽  
...  
Keyword(s):  
Bone Formation ◽  
Tricalcium Phosphate ◽  
Wistar Rats ◽  
Materials Science ◽  
Bone Matrix ◽  
Bone Substitutes ◽  
Biological Behavior ◽  
Ctrl Group ◽  
Beta Tricalcium Phosphate ◽  
Osteoblast Activity

The development of new bone substitutes has become an area of great interest in materials science. In fact, hydroxyapatite is the most commonly used biomaterial in defects that require bone reconstruction, and that is certainly why the discovery of new products with its formulation has been increasing continuously. The aim of this study was to analyze the biological behavior of a xenogeneic hydroxyapatite widely disclosed in the literature and a synthetic nano-hydroxyapatite/Beta tricalcium phosphate in critical defects in the calvaria of Wistar rats. For this, the groups were divided as follows: 24 adult male Wistar rats were used, weighing between 300 and 350 g, in three groups with eight animals each. In the CTRL group (control), only the clot was kept, without material insertion; in the Bioss group (bovine hydroxyapatite), Bio Oss®—Gleistlich® was introduced; and in the Blue Bone group (REG), the defect was filled in with synthetic nano-hydroxyapatite associated with betatriphosphate of calcium, Blue Bone®—Regener®. According to the results in Goldner’s Trichromics, we can observe a higher percentage of newly formed bone matrix in the REG group than in the CTRL and Bioss groups; in the VEGF, we had a more adequate cell modulation for blood vessel formation in the Blue Bone group (REG) compared to the Bioss and CTRL groups, while in osteopontin, a higher percentage of bone formation was observed in the Blue Bone group (REG) and Bioss group when compared to the CTRL group. We conclude that bone formation, mitosis-inducing cell modulation and main osteoblast activity were higher in the Blue Bone group (REG) than in the CTRL and Bioss groups.

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