Chitosan scaffolds for osteochondral tissue regeneration

2010 ◽  
Vol 95A (4) ◽  
pp. 1132-1141 ◽  
Author(s):  
Ander Abarrategi ◽  
Yaiza Lópiz-Morales ◽  
Viviana Ramos ◽  
Ana Civantos ◽  
Luis López-Durán ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Chitosan Scaffolds ◽  
Osteochondral Tissue

scholarly journals A Rabbit Femoral Condyle Defect Model for Assessment of Osteochondral Tissue Regeneration

2020 ◽  
Vol 26 (11) ◽  
pp. 554-564
Author(s):  
Jason L. Guo ◽  
Yu Seon Kim ◽  
Elysse A. Orchard ◽  
Jeroen J.J.P. van den Beucken ◽  
John A. Jansen ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Femoral Condyle ◽  
Defect Model ◽  
Osteochondral Tissue

scholarly journals Peptide-biofunctionalization of biomaterials for osteochondral tissue regeneration in early stage osteoarthritis: challenges and opportunities

2019 ◽  
Vol 7 (7) ◽  
pp. 1027-1044 ◽  
Author(s):  
D. Bicho ◽  
S. Ajami ◽  
C. Liu ◽  
R. L. Reis ◽  
J. M. Oliveira
Keyword(s):  
Articular Cartilage ◽  
Subchondral Bone ◽  
Tissue Regeneration ◽  
Early Stage ◽  
Degenerative Joint Disease ◽  
Synovial Inflammation ◽  
Joint Disease ◽  
Progressive Deterioration ◽  
Challenges And Opportunities ◽  
Osteochondral Tissue

Osteoarthritis is a degenerative joint disease characterized by the progressive deterioration of articular cartilage, synovial inflammation and changes in periarticular and subchondral bone, being a leading cause of disability.

scholarly journals Silk Fibroin/Collagen/Chitosan Scaffolds Cross-Linked by a Glyoxal Solution as Biomaterials toward Bone Tissue Regeneration

Materials ◽  
2020 ◽  
Vol 13 (15) ◽  
pp. 3433
Author(s):  
Sylwia Grabska-Zielińska ◽  
Alina Sionkowska ◽  
Catarina C. Coelho ◽  
Fernando J. Monteiro
Keyword(s):  
Mechanical Properties ◽  
Silk Fibroin ◽  
Tissue Regeneration ◽  
Three Dimensional ◽  
Bone Tissue Regeneration ◽  
New Materials ◽  
Swelling Degree ◽  
Chitosan Scaffolds ◽  
Measured Density ◽  
Scanning Electron

In this study, three-dimensional materials based on blends of silk fibroin (SF), collagen (Coll), and chitosan (CTS) cross-linked by glyoxal solution were prepared and the properties of the new materials were studied. The structure of the composites and the interactions between scaffold components were studied using FTIR spectroscopy. The microstructure was observed using a scanning electron microscope. The following properties of the materials were measured: density and porosity, moisture content, and swelling degree. Mechanical properties of the 3D materials under compression were studied. Additionally, the metabolic activity of MG-63 osteoblast-like cells on materials was examined. It was found that the materials were characterized by a high swelling degree (up to 3000% after 1 h of immersion) and good porosity (in the range of 80–90%), which can be suitable for tissue engineering applications. None of the materials showed cytotoxicity toward MG-63 cells.

Sign in / Sign up

Export Citation Format

Share Document