Surface modification of medical-grade polyurethane by cyanurchloride-activated tetraether lipid (a new approach for bacterial antiadhesion)

2008 ◽  
Vol 84A (3) ◽  
pp. 672-681 ◽  
Author(s):  
Ananthu Sateesh ◽  
Jürgen Vogel ◽  
Evelyn Dayss ◽  
Beate Fricke ◽  
Karin Dölling ◽  
...  
Keyword(s):  
Surface Modification ◽  
Lipid A ◽  
New Approach ◽  
Tetraether Lipid ◽  
Medical Grade

A Novel Approach for Metal Surface Modification

2007 ◽  
Vol 280-283 ◽  
pp. 1805-1806
Author(s):  
Zhi Jun Cao ◽  
Jia Chen Liu ◽  
Li Bin Liu ◽  
Hao Ye ◽  
Yan Qiu Wei
Keyword(s):  
Surface Modification ◽  
Wear Rate ◽  
Charge State ◽  
Metal Surface ◽  
Surface Hardness ◽  
Metallic Surface ◽  
New Approach ◽  
Novel Approach ◽  
Complex Shapes ◽  
Enhanced Surface

A new approach was developed for surface modification of metallic surface. By treating nano-zirconia particles and metal surface in different charge state, nano-zirconia particles can be dispersedly inlaid in metal surface owing to electrostatic and nanometer effects. By using this method, metal components of complex shapes, especially those having inside surfaces, might be easily improved, i.e., enhanced surface hardness and wear rate.

New approach to improve polymer-Mg interface in biodegradable PLA/Mg composites through particle surface modification

2020 ◽  
Vol 383 ◽  
pp. 125285 ◽  
Author(s):  
Ana Ferrandez-Montero ◽  
Marcela Lieblich ◽  
Rosario Benavente ◽  
José Luis González-Carrasco ◽  
Begoña Ferrari
Keyword(s):  
Surface Modification ◽  
Particle Surface ◽  
New Approach

scholarly journals Analysis of the Networks Controlling the Antimicrobial-Peptide-Dependent Induction of Klebsiella pneumoniae Virulence Factors

2011 ◽  
Vol 79 (9) ◽  
pp. 3718-3732 ◽  
Author(s):  
Enrique Llobet ◽  
Miguel A. Campos ◽  
Paloma Giménez ◽  
David Moranta ◽  
José A. Bengoechea
Keyword(s):  
Klebsiella Pneumoniae ◽  
Defense Mechanisms ◽  
Lipid A ◽  
Multidrug Resistant ◽  
Cross Resistance ◽  
New Approach ◽  
Content Type ◽  
Signaling Systems ◽  
Transcriptional Changes ◽  
Initial Target

ABSTRACTAntimicrobial peptides (APs) impose a threat to the survival of pathogens, and it is reasonable to postulate that bacteria have developed strategies to counteract them. Polymyxins are becoming the last resort to treat infections caused by multidrug-resistant Gram-negative bacteria and, similar to APs, they interact with the anionic lipopolysaccharide. Given that polymyxins and APs share the initial target, it is possible that bacterial defense mechanisms against polymyxins will be also effective against host APs. We sought to determine whether exposure to polymyxin will increaseKlebsiella pneumoniaeresistance to host APs. Indeed, exposure ofK. pneumoniaeto polymyxin induces cross-resistance not only to polymyxin itself but also to APs present in the airways. Polymyxin treatment upregulates the expression of the capsule polysaccharide operon and the loci required to modify the lipid A with aminoarabinose and palmitate with a concomitant increase in capsule and lipid A species containing such modifications. Moreover, these surface changes contribute to APs resistance and also to polymyxin-induced cross-resistance to APs. Bacterial loads of lipid A mutants in trachea and lungs of intranasally infected mice were lower than those of wild-type strain. PhoPQ, PmrAB, and the Rcs system govern polymyxin-induced transcriptional changes, and there is a cross talk between PhoPQ and the Rcs system. Our findings support the notion thatKlebsiellaactivates a defense program against APs that is controlled by three signaling systems. Therapeutic strategies directed to prevent the activation of this program could be a new approach worth exploring to facilitate the clearance of the pathogen from the airways.

New Method for Surface Modification of Nanoporous Aluminum Oxide Membranes Using Tetraether Lipid

2006 ◽  
Vol 2 (1) ◽  
pp. 16-22 ◽  
Author(s):  
Steffen Müller ◽  
Monika Pfannmöller ◽  
Nico Teuscher ◽  
Andreas Heilmann ◽  
Ulrich Rothe
Keyword(s):  
Surface Modification ◽  
Aluminum Oxide ◽  
New Method ◽  
Tetraether Lipid ◽  
Oxide Membranes

Layer-by-Layer Surface Modification of Fruits with Edible Nano-Coatings

2012 ◽  
Vol 229-231 ◽  
pp. 2745-2748 ◽  
Author(s):  
Paveenuch Kittitheeranun ◽  
Stephan Thierry Dubas ◽  
Luxsana Dubas
Keyword(s):  
Surface Modification ◽  
Contact Angles ◽  
Layer By Layer ◽  
New Approach ◽  
Vis Spectroscopy ◽  
Coating Method ◽  
Anti Oxidant ◽  
Poly Styrene Sulfonate ◽  
Fruit Surface ◽  
Modification Of The Surface

A new method for the surface modification of the surface of fruits based on the Layer-by-Layer (LbL) deposition of polyelectrolyte multilayers (PEM) is presented. Mangoes fruits were coated by sequential dipping in solutions of either Poly(diallyldimethylammonium chloride), (PDADMAC) or Poly(styrene sulfonate sodium salt) (PSS). After the deposition of only few polyelectrolyte layers, the skin of the fruits was changed from hydrophobic to hydrophilic as shown by contact angles measurements decreasing from 90 to 10. Fourier transform infrared spectroscopy (FTIR) was used to confirm the deposition of the PEM coating on the fruit which was then used as a matrix to load curcumin as model compound. Ultraviolet Visible (UV-Vis) spectroscopy was used to evaluate the amount of a curcumin loaded on the fruit surface as a function of the thickness of the film by indirect leaching in ethanol. This coating method provides a new approach to dope active compound on the fruit surface such as anti-oxidant, fragrance, color and other nutriment which could increase the market value of fruits.

scholarly journals New Approach toward Laser-Assisted Modification of Biocompatible Polymers Relevant to Neural Interfacing Technologies

Polymers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 3004
Author(s):  
Nadya Stankova ◽  
Anastas Nikolov ◽  
Ekaterina Iordanova ◽  
Georgi Yankov ◽  
Nikolay Nedyalkov ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Neurological Diseases ◽  
Chemical Activation ◽  
Multielectrode Arrays ◽  
Platinum Black ◽  
Homogeneous Microstructure ◽  
New Approach ◽  
Tight Contact ◽  
Medical Grade ◽  
Neural Interfacing

We report on a new approach toward a laser-assisted modification of biocompatible polydimethylsiloxane (PDMS) elastomers relevant to the fabrication of stretchable multielectrode arrays (MEAs) devices for neural interfacing technologies. These applications require high-density electrode packaging to provide a high-resolution integrating system for neural stimulation and/or recording. Medical grade PDMS elastomers are highly flexible with low Young’s modulus < 1 MPa, which are similar to soft tissue (nerve, brain, muscles) among the other known biopolymers, and can easily adjust to the soft tissue curvatures. This property ensures tight contact between the electrodes and tissue and promotes intensive development of PDMS-based MEAs interfacing devices in the basic neuroscience, neural prosthetics, and hybrid bionic systems, connecting the human nervous system with electronic or robotic prostheses for restoring and treating neurological diseases. By using the UV harmonics 266 and 355 nm of Nd:YAG laser medical grade PDMS elastomer is modified by ns-laser ablation of in water. A new approach of processing is proposed to (i) activate the surface and to obtain tracks with (ii) symmetric U-shaped profiles and (iii) homogeneous microstructure This technology provides miniaturization of the device and successful functionalization by electroless metallization of the tracks with platinum (Pt) without preliminary sensitization by tin (Sn) and chemical activation by palladium (Pd). As a result, platinum black layers with a cauliflower-like structure with low values of sheet resistance between 1 and 8 Ω/sq are obtained.

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