Changes in mechanical properties and cellularity during long-term culture of collagen fiber ACL reconstruction scaffolds

2005 ◽  
Vol 73A (4) ◽  
pp. 388-397 ◽  
Author(s):  
Andrea B. Caruso ◽  
Michael G. Dunn
Keyword(s):  
Mechanical Properties ◽  
Acl Reconstruction ◽  
Collagen Fiber ◽  
Long Term Culture

Relationship Between Mechanical Properties and Collagen Structure of Closed and Open Wounds

1988 ◽  
Vol 110 (4) ◽  
pp. 352-356 ◽  
Author(s):  
Charles J. Doillon ◽  
Michael G. Dunn ◽  
Frederick H. Silver
Keyword(s):  
Mechanical Properties ◽  
Tensile Strength ◽  
Ultimate Tensile Strength ◽  
Collagen Fiber ◽  
Fiber Diameter ◽  
Normal Skin ◽  
Collagen Fibers ◽  
Collagen Structure ◽  
Collagen Network

Mechanical properties and collagen structure of excisional wounds left open are compared with wounds closed by clips. In both wound models, collagen fiber diameter increases with time post-wounding and is related to tensile strength. Clipped wounds show a higher ultimate tensile strength and tangent modulus compared with open wounds. In clipped wounds, newly deposited collagen appears as a biaxially oriented network as observed in normal skin. In open wounds a delay in the organization of the collagen network is observed and parallel wavy-shaped ribbons of collagen fibers are deposited. At long term, the high extensibility observed in open wounds may be due to the sliding of ribbons of collagen fibers past each other.

Engineering anisotropic cardiac monolayers on microelectrode arrays for non-invasive analyses of electrophysiological properties

The Analyst ◽  
2020 ◽  
Vol 145 (1) ◽  
pp. 139-149 ◽  
Author(s):  
Ahmad Alassaf ◽  
Gulistan Tansik ◽  
Vera Mayo ◽  
Laura Wubker ◽  
Daniel Carbonero ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Microelectrode Arrays ◽  
Cardiac Tissues ◽  
Long Term Culture ◽  
Electrophysiological Properties ◽  
Non Invasive

Engineering cardiac tissues with physiological architectural and mechanical properties on microelectrode arrays enables long term culture and non-invasive collection of electrophysiological readouts.

scholarly journals Provision of exogenous lipid interacts with maternal BMI to affect human embryo survival in long term culture

2017 ◽  
Vol 108 (3) ◽  
pp. e59-e60
Author(s):  
R. Kile ◽  
Y. Yuan ◽  
H. Silz ◽  
S. McCormick ◽  
W.B. Schoolcraft ◽  
...  
Keyword(s):  
Human Embryo ◽  
Embryo Survival ◽  
Long Term Culture ◽  
Exogenous Lipid ◽  
Maternal Bmi

scholarly journals Mechanical Properties of Cement-Treated Soil Mixed with Cellulose Nanofibre

2021 ◽  
Vol 11 (14) ◽  
pp. 6425
Author(s):  
Hidenori Takahashi ◽  
Shinya Omori ◽  
Hideyuki Asada ◽  
Hirofumi Fukawa ◽  
Yusuke Gotoh ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Flexural Strength ◽  
Geotechnical Engineering ◽  
Strength Development ◽  
Soft Ground ◽  
Wood Cellulose ◽  
Treated Soil ◽  
Made In ◽  
Cement Treatment

Cellulose nanofibre (CNF), a material composed of ultrafine fibres of wood cellulose fibrillated to nano-order level, is expected to be widely used because of its excellent properties. However, in the field of geotechnical engineering, almost no progress has been made in the development of techniques for using CNFs. The authors have focused on the use of CNF as an additive in cement treatment for soft ground, where cement is added to solidify the ground, because CNF can reduce the problems associated with cement-treated soil. This paper presents the results of a study on the method of mixing CNF, the strength and its variation obtained by adding CNF, and the change in permeability. CNF had the effect of mixing the cement evenly and reducing the variation in the strength of the treated soil. The CNF mixture increased the strength at the initial age but reduced the strength development in the long term. The addition of CNF also increased the flexural strength, although it hardly changed the permeability.

scholarly journals Long-term culture of SH-SY5Y neuroblastoma cells in the absence of neurotrophins: a novel model of neuronal ageing

2021 ◽  
pp. 109301
Author(s):  
Lisa Strother ◽  
Gareth B. Miles ◽  
Alison R. Holiday ◽  
Ying Cheng ◽  
Gayle H. Doherty
Keyword(s):  
Neuroblastoma Cells ◽  
Long Term Culture ◽  
Novel Model

scholarly journals High-strength and fibrous capsule–resistant zwitterionic elastomers

2021 ◽  
Vol 7 (1) ◽  
pp. eabc5442
Author(s):  
Dianyu Dong ◽  
Caroline Tsao ◽  
Hsiang-Chieh Hung ◽  
Fanglian Yao ◽  
Chenjue Tang ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Mechanical Strength ◽  
High Strength ◽  
Design Principles ◽  
Fibrous Capsule ◽  
High Mechanical Strength ◽  
Capsule Formation ◽  
Locking Mechanism ◽  
Fibrous Capsule Formation

The high mechanical strength and long-term resistance to the fibrous capsule formation are two major challenges for implantable materials. Unfortunately, these two distinct properties do not come together and instead compromise each other. Here, we report a unique class of materials by integrating two weak zwitterionic hydrogels into an elastomer-like high-strength pure zwitterionic hydrogel via a “swelling” and “locking” mechanism. These zwitterionic-elastomeric-networked (ZEN) hydrogels are further shown to efficaciously resist the fibrous capsule formation upon implantation in mice for up to 1 year. Such materials with both high mechanical properties and long-term fibrous capsule resistance have never been achieved before. This work not only demonstrates a class of durable and fibrous capsule–resistant materials but also provides design principles for zwitterionic elastomeric hydrogels.

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