scholarly journals One‐to‐one registration of en‐face optical coherence tomography attenuation coefficients with histology of a prostatectomy specimen

2018 ◽  
Vol 12 (4) ◽  
pp. e201800274 ◽  
Author(s):  
Abel Swaan ◽  
Berrend G. Muller ◽  
Leah S. Wilk ◽  
Mitra Almasian ◽  
Rob A. A. van Kollenburg ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Attenuation Coefficients ◽  
En Face ◽  
Prostatectomy Specimen ◽  
One To One

scholarly journals En face image-based classification of diabetic macular edema using swept source optical coherence tomography

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Atsushi Fujiwara ◽  
Yuki Kanzaki ◽  
Shuhei Kimura ◽  
Mio Hosokawa ◽  
Yusuke Shiode ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Outer Nuclear Layer ◽  
Subretinal Fluid ◽  
Plexiform Layer ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Swept Source ◽  
En Face

AbstractThis retrospective study was performed to classify diabetic macular edema (DME) based on the localization and area of the fluid and to investigate the relationship of the classification with visual acuity (VA). The fluid was visualized using en face optical coherence tomography (OCT) images constructed using swept-source OCT. A total of 128 eyes with DME were included. The retina was segmented into: Segment 1, mainly comprising the inner nuclear layer and outer plexiform layer, including Henle’s fiber layer; and Segment 2, mainly comprising the outer nuclear layer. DME was classified as: foveal cystoid space at Segment 1 and no fluid at Segment 2 (n = 24), parafoveal cystoid space at Segment 1 and no fluid at Segment 2 (n = 25), parafoveal cystoid space at Segment 1 and diffuse fluid at Segment 2 (n = 16), diffuse fluid at both segments (n = 37), and diffuse fluid at both segments with subretinal fluid (n = 26). Eyes with diffuse fluid at Segment 2 showed significantly poorer VA, higher ellipsoid zone disruption rates, and greater central subfield thickness than did those without fluid at Segment 2 (P < 0.001 for all). These results indicate the importance of the localization and area of the fluid for VA in DME.

scholarly journals Comparison of swept-source versus spectral-domain optical coherence tomography angiography for detection of macular neovascularization

2021 ◽  
Author(s):  
Anna Lentzsch ◽  
Laura Schöllhorn ◽  
Christel Schnorr ◽  
Robert Siggel ◽  
Sandra Liakopoulos
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Swept Source ◽  
En Face ◽  
Increased Sensitivity ◽  
Sensitivity Specificity ◽  
Subretinal Hyperreflective Material

Abstract Purpose To compare swept-source (SS) versus spectral-domain (SD) optical coherence tomography angiography (OCTA) for the detection of macular neovascularization (MNV). Methods In this prospective cohort study, 72 eyes of 54 patients with subretinal hyperreflective material (SHRM) and/or pigment epithelial detachment (PED) on OCT possibly corresponding to MNV in at least one eye were included. OCTA scans were acquired using two devices, the PLEX Elite 9000 SS-OCTA and the Spectralis SD-OCTA. Fluorescein angiography (FA) was used as reference. Two graders independently evaluated en face OCTA images using a preset slab as well as a manually modified slab, followed by a combination of en face and cross-sectional OCTA. Results Sensitivity (specificity) for the automated slabs was 51.7% (93.0%) for SS-OCTA versus 58.6% (95.3%) for SD-OCTA. Manual modification of segmentation increased sensitivity to 79.3% for SS-OCTA but not for SD-OCTA (58.6%). The combination of en face OCTA with cross-sectional OCTA reached highest sensitivity values (SS-OCTA: 82.8%, SD-OCTA: 86.2%), and lowest number of cases with discrepancies between SS-OCTA and SD-OCTA (4.2%). Fleiss kappa as measure of concordance between FA, SS-OCTA, and SD-OCTA was 0.56 for the automated slabs, 0.60 for the manual slabs, and 0.73 (good agreement) for the combination of en face OCTA with cross-sectional OCTA. Concordance to FA was moderate for the automated slabs and good for manual slabs and combination with cross-sectional OCTA of both devices. Conclusion Both devices reached comparable results regarding the detection of MNV on OCTA. Sensitivity for MNV detection and agreement between devices was best when evaluating a combination of en face and cross-sectional OCTA.

Multiple-depth en face optical coherence tomography using active recirculation loops

2010 ◽  
Vol 35 (13) ◽  
pp. 2296 ◽  
Author(s):  
Liviu Neagu ◽  
Adrian Bradu ◽  
Lisha Ma ◽  
James W. Bloor ◽  
Adrian Gh. Podoleanu
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
En Face

Su2030 En Face Optical Coherence Tomography Visualization of Mucosal Surface Patterns for Identifying Early Malignancy in the Upper GI Tract

2015 ◽  
Vol 148 (4) ◽  
pp. S-579
Author(s):  
Osman O. Ahsen ◽  
Hsiang-Chieh Lee ◽  
Kaicheng Liang ◽  
Michael G. Giacomelli ◽  
Zhao Wang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Mucosal Surface ◽  
Optical Coherence ◽  
Gi Tract ◽  
Upper Gi ◽  
En Face ◽  
Surface Patterns ◽  
Upper Gi Tract

scholarly journals Topography and volume measurements of the optic nerve using en-face optical coherence tomography

2001 ◽  
Vol 9 (10) ◽  
pp. 533 ◽  
Author(s):  
John A. Rogers ◽  
Adrian Gh. Podoleanu ◽  
George M. Dobre ◽  
David A. Jackson ◽  
Fred W. Fitzke
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optical Coherence ◽  
En Face ◽  
Volume Measurements

scholarly journals Alterations in Retinal Layer Thickness and Reflectance at Different Stages of Diabetic Retinopathy by En Face Optical Coherence Tomography

2016 ◽  
Vol 57 (9) ◽  
pp. OCT341 ◽  
Author(s):  
Justin Wanek ◽  
Norman P. Blair ◽  
Felix Y. Chau ◽  
Jennifer I. Lim ◽  
Yannek I. Leiderman ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Layer Thickness ◽  
Retinal Layer ◽  
Optical Coherence ◽  
En Face
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