scholarly journals Retinal Blood Flow Response to Hyperoxia Measured With En Face Doppler Optical Coherence Tomography

2016 ◽  
Vol 57 (9) ◽  
pp. OCT141 ◽  
Author(s):  
Alex D. Pechauer ◽  
Ou Tan ◽  
Liang Liu ◽  
Yali Jia ◽  
Vivian Hou ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Retinal Blood Flow ◽  
Optical Coherence ◽  
Blood Flow Response ◽  
Flow Response ◽  
En Face ◽  
Doppler Optical Coherence Tomography

scholarly journals Assessing total retinal blood flow in diabetic retinopathy using multiplane en face Doppler optical coherence tomography

2017 ◽  
Vol 102 (1) ◽  
pp. 126-130 ◽  
Author(s):  
Alex D Pechauer ◽  
Thomas S Hwang ◽  
Ahmed M Hagag ◽  
Liang Liu ◽  
Ou Tan ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Diabetic Retinopathy ◽  
Retinal Blood Flow ◽  
Optical Coherence ◽  
Data Set ◽  
Doppler Oct ◽  
Significant Difference ◽  
En Face ◽  
Doppler Optical Coherence Tomography

AimTo assess total retinal blood flow (TRBF) in diabetic retinopathy (DR) using multiplane en face Doppler optical coherence tomography (OCT).MethodsA 70 kHz spectral-domain OCT system scanned a 2×2 mm area centred at the optic disc of the eyes with DR and healthy participants. The multiplane en face Doppler OCT algorithm generated a three-dimensional volumetric data set consisting of 195 en face planes. The TRBF was calculated from the maximum flow values of each branching retinal vein at an optimised en face plane. DR severity was graded according to the international clinical classification system. The generalised linear model method was used to compare flow values between DR groups and the control group.ResultsA total of 71 eyes from 71 participants were included. Ten eyes were excluded due to poor image quality. The within-visit repeatability of scans was 4.1% (coefficient of variation). There was no significant difference in the TRBF between the healthy (46.7±10.2 µL/min) and mild/moderate non-proliferative DR (44.9±12.6 µL/min) groups. The TRBF in severe non-proliferative DR (39.1±12.6 µL/min) and proliferative DR (28.9±8.85 µL/min) groups were significantly lower (p=0.04 and p<0.0001, respectively) than that of the healthy group. TRBF was correlated with DR disease severity (p<0.0001, linear trend test).ConclusionThe novel multiplane en face Doppler OCT method provided reliable measurements of TRBF in DR eyes. This may be a useful tool in understanding the pathophysiology of DR.

scholarly journals Total retinal blood flow measurement by three beam Doppler optical coherence tomography

2016 ◽  
Vol 7 (2) ◽  
pp. 287 ◽  
Author(s):  
Richard Haindl ◽  
Wolfgang Trasischker ◽  
Andreas Wartak ◽  
Bernhard Baumann ◽  
Michael Pircher ◽  
...  
Keyword(s):  
Blood Flow ◽  
Optical Coherence Tomography ◽  
Flow Measurement ◽  
Retinal Blood Flow ◽  
Blood Flow Measurement ◽  
Optical Coherence ◽  
Doppler Optical Coherence Tomography
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