Trimodal system for in vivo skin cancer screening with combined optical coherence tomography-Raman and colocalized optoacoustic measurements

2018 ◽  
Vol 11 (6) ◽  
pp. e201700288 ◽  
Author(s):  
Arthur Varkentin ◽  
Mikhail Mazurenka ◽  
Elias Blumenröther ◽  
Lea Behrendt ◽  
Steffen Emmert ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Cancer Screening ◽  
Skin Cancer ◽  
Optical Coherence ◽  
Skin Cancer Screening

scholarly journals PRELIMINARY STUDY ON SKIN CANCER DETECTION IN SENCAR MICE USING MUELLER OPTICAL COHERENCE TOMOGRAPHY

2009 ◽  
Vol 02 (03) ◽  
pp. 289-294 ◽  
Author(s):  
MILOŠ TODOROVIĆ ◽  
SHULIANG JIAO ◽  
GEORGE STOICA ◽  
LIHONG V. WANG
Keyword(s):  
Optical Coherence Tomography ◽  
Skin Cancer ◽  
Cancer Detection ◽  
Morphological Changes ◽  
Optical Coherence ◽  
Optical Scanning ◽  
Integrated Optical ◽  
Skin Cancer Detection ◽  
Continuous Source

We report on the use of a fiber-based Mueller-matrix optical coherence tomography (OCT) system with continuous source-polarization modulation for in vivo imaging of early stages of skin cancer in SENCAR mice. A homemade hand-held probe with integrated optical scanning and beam delivering optics was coupled in the sample arm. The OCT images show the morphological changes in skin resulting from pre-cancerous papilloma formations that are consistent with histology, thus demonstrating the system's potential for early skin cancer detection.

scholarly journals Development of a combined OCT-Raman probe for the prospective in vivo clinical melanoma skin cancer screening

2017 ◽  
Vol 88 (10) ◽  
pp. 105103 ◽  
Author(s):  
M. Mazurenka ◽  
L. Behrendt ◽  
M. Meinhardt-Wollweber ◽  
U. Morgner ◽  
B. Roth
Keyword(s):  
Cancer Screening ◽  
Skin Cancer ◽  
Skin Cancer Screening ◽  
Raman Probe ◽  
Melanoma Skin

258: Diagnosis and Intraoperative Staging of Bladder Disease by in-vivo Optical Coherence Tomography (OCT)

2004 ◽  
Vol 171 (4S) ◽  
pp. 68-68 ◽  
Author(s):  
Markus D. Sachs ◽  
Dmitry Daniltchenko ◽  
Eva Lankenau ◽  
Frank Koenig ◽  
Gerion Huettmann ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Bladder Disease

scholarly journals Evaluating Retinal and Choroidal Perfusion Changes after Isometric and Dynamic Activity Using Optical Coherence Tomography Angiography

Diagnostics ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 808
Author(s):  
Max Philipp Brinkmann ◽  
Nikolas Xavier Kibele ◽  
Michelle Prasuhn ◽  
Vinodh Kakkassery ◽  
Mario Damiano Toro ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Isometric Exercise ◽  
Dynamic Exercise ◽  
Exercise Heart Rate ◽  
Optical Coherence ◽  
Dynamic Activity ◽  
Capillary Plexus ◽  
Choroidal Perfusion

Optical coherence tomography angiography (OCTA) is a non-invasive tool for imaging and quantifying the retinal and choroidal perfusion state in vivo. This study aimed to evaluate the acute effects of isometric and dynamic exercise on retinal and choroidal sublayer perfusion using OCTA. A pilot study was conducted on young, healthy participants, each of whom performed a specific isometric exercise on the first day and a dynamic exercise the day after. At baseline and immediately after the exercise, heart rate (HR), mean arterial pressure (MAP), superficial capillary plexus perfusion (SCPP), deep capillary plexus perfusion (DCPP), choriocapillaris perfusion (CCP), Sattlers’s layer perfusion (SLP), and Haller’s layer perfusion (HLP) were recorded. A total of 34 eyes of 34 subjects with a mean age of 32.35 ± 7.87 years were included. HR as well as MAP increased significantly after both types of exercise. Both SCPP and DCPP did not show any significant alteration due to isometric or dynamic exercise. After performing dynamic exercise, CCP, SLP, as well as HLP significantly increased. Changes in MAP correlated significantly with changes in HLP after the dynamic activity. OCTA-based analysis in healthy adults following physical activity demonstrated a constant retinal perfusion, supporting the theory of autoregulatory mechanisms. Dynamic exercise, as opposed to isometric activity, significantly changed choroidal perfusion. OCTA imaging may represent a novel and sensitive tool to expand the diagnostic spectrum in the field of sports medicine.

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