Fiber-optic probes for in vivo depth-resolved neuron-activity mapping

2010 ◽  
Vol 3 (10-11) ◽  
pp. 660-669 ◽  
Author(s):  
Lyubov V. Doronina-Amitonova ◽  
Il'ya V. Fedotov ◽  
Olga I. Ivashkina ◽  
Marina A. Zots ◽  
Andrei B. Fedotov ◽  
...  
Keyword(s):  
Fiber Optic ◽  
Neuron Activity ◽  
Fiber Optic Probes

scholarly journals Optical pH Detection with U-Shaped Fiber-Optic Probes and Absorption Transducers

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Jakub Zajíc ◽  
Lenka Traplová ◽  
Vlastimil Matějec ◽  
Marie Pospíšilová ◽  
Ivo Bartoň
Keyword(s):  
Fiber Optic ◽  
Ph Monitoring ◽  
Porous Silica ◽  
Bromothymol Blue ◽  
Small Sample ◽  
Physiological Processes ◽  
Ph Indicators ◽  
Fiber Optic Probes ◽  
Ph Range

In medicine knowledge of pH values can provide us with information not only about the patients’ status but also about physiological processes in the patient’s body. Measurements of pH in small-sample volumes and online pH monitoring in vivo can be employed to obtain such information. For such measurements we have developed and investigated U-shaped fiber-optic probes with immobilized pH indicators in this paper. U-shaped probes with a diameter of about 2 mm were prepared. Three different pH indicators, methyl red, methyl orange, and bromothymol blue, were immobilized in two types of matrices, namely, porous silica (PS) and ethylcellulose (EC), and applied on the U-shaped probes. Changes in spectra of transmitted power were measured and calibration curves were determined from these spectra. It has been found that a working pH range of prepared probes was from 3.1 to 7.6. The maximum sensitivity was about 0.1 1/pH unit. Effects of structural relaxations of detection layers and indicator leaching observed in experiments are discussed.

scholarly journals Modelling, Design and Validation of Spatially Resolved Reflectance Based Fiber Optic Probe for Epithelial Precancer Diagnostics

2020 ◽  
Vol 10 (24) ◽  
pp. 8836
Author(s):  
Pankaj Singh ◽  
Prabodh Pandey ◽  
Shivam Shukla ◽  
Naren Naik ◽  
Asima Pradhan
Keyword(s):  
Fiber Optic ◽  
Numerical Study ◽  
Fiber Optic Probe ◽  
Scattering Coefficients ◽  
Spatially Resolved ◽  
Fiber Optic Probes ◽  
Diagnosis Of Cancer ◽  
Optic Probe ◽  
In Vivo Diagnosis

Fiber-optic probes are imperative for in-vivo diagnosis of cancer. Depending on the access to a diseased organ and the mutations one aims to sense, the probe designs vary. We carry out a detailed numerical study of the efficacy of the common probe geometries for epithelial cancer characterization based on spatially resolved reflectance data. As per the outcomes of this comparative study, a probe has been manufactured and using Monte Carlo look up table based inversion scheme, the absorption and scattering coefficients of the epithelium mimicking top layer have been recovered from noisy synthetic as well as experimental data.

Study of Fiber-Optic Probes for in vivo Medical Raman Spectroscopy

1999 ◽  
Vol 53 (6) ◽  
pp. 619-627 ◽  
Author(s):  
Martin G. Shim ◽  
Brian C. Wilson ◽  
Eric Marple ◽  
Michael Wach
Keyword(s):  
Raman Spectroscopy ◽  
Fiber Optic ◽  
Fiber Optic Probes

Fiber-Optic Probes for in Vivo Raman Spectroscopy in the High-Wavenumber Region

2005 ◽  
Vol 77 (20) ◽  
pp. 6747-6752 ◽  
Author(s):  
Luís F. Santos ◽  
Rolf Wolthuis ◽  
S. Koljenović ◽  
Rui M. Almeida ◽  
Gerwin J. Puppels
Keyword(s):  
Raman Spectroscopy ◽  
Fiber Optic ◽  
Fiber Optic Probes ◽  
In Vivo Raman Spectroscopy ◽  
Wavenumber Region

Radio-opaque isotropic fiber optic probes for in vivo photodynamic therapy dosimetry

1994 ◽  
Author(s):  
Emma J. Hudson ◽  
Mark R. Stringer ◽  
Hugo J. van Staveren ◽  
Michael A. Smith
Keyword(s):  
Photodynamic Therapy ◽  
Fiber Optic ◽  
Fiber Optic Probes

Evaluation of fiber optic probes for in-vivo Raman spectroscopy

1998 ◽  
Author(s):  
Martin G. Shim ◽  
Brian C. Wilson ◽  
Eric Marple ◽  
Michael L. Wach
Keyword(s):  
Raman Spectroscopy ◽  
Fiber Optic ◽  
Fiber Optic Probes ◽  
In Vivo Raman Spectroscopy

Infrared fiber optic probes for evaluation of musculoskeletal tissue pathology

2014 ◽  
Author(s):  
Mugdha Padalkar ◽  
Cushla McGoverin ◽  
Quam Onigbanjo ◽  
Richard Spencer ◽  
Scott Barbash ◽  
...  
Keyword(s):  
Fiber Optic ◽  
Musculoskeletal Tissue ◽  
Fiber Optic Probes

Design optimization of fiber optic probes for remote fluorescence spectroscopy

2009 ◽  
Vol 282 (14) ◽  
pp. 2676-2684 ◽  
Author(s):  
G.K. Bhowmick ◽  
Nutan Gautam ◽  
L.M. Gantayet
Keyword(s):  
Fluorescence Spectroscopy ◽  
Design Optimization ◽  
Fiber Optic ◽  
Fiber Optic Probes
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