Aluminium oxide nanoparticles induced morphological changes, cytotoxicity and oxidative stress in Chinook salmon (CHSE-214) cells

2015 ◽  
Vol 35 (10) ◽  
pp. 1133-1140 ◽  
Author(s):  
Koigoora Srikanth ◽  
Amit Mahajan ◽  
Eduarda Pereira ◽  
Armando Costa Duarte ◽  
Janapala Venkateswara Rao
Keyword(s):  
Oxidative Stress ◽  
Chinook Salmon ◽  
Morphological Changes ◽  
Aluminium Oxide ◽  
Oxide Nanoparticles ◽  
Aluminium Oxide Nanoparticles ◽  
And Oxidative Stress

Assessment of cytotoxicity and oxidative stress induced by titanium oxide nanoparticles on Chinook salmon cells

2015 ◽  
Vol 22 (20) ◽  
pp. 15571-15578 ◽  
Author(s):  
Koigoora Srikanth ◽  
Eduarda Pereira ◽  
Armando C Duarte ◽  
Iqbal Ahmad ◽  
Janapala Venkateswara Rao
Keyword(s):  
Oxidative Stress ◽  
Titanium Oxide ◽  
Chinook Salmon ◽  
Oxide Nanoparticles ◽  
Titanium Oxide Nanoparticles ◽  
And Oxidative Stress

scholarly journals Effect of aluminium oxide nanoparticles on the enzymatic activity on microorganisms of activated sludge

2018 ◽  
Vol 44 ◽  
pp. 00033 ◽  
Author(s):  
Nina Doskocz ◽  
Katarzyna Affek ◽  
Monika Załęska-Radziwiłł
Keyword(s):  
Enzymatic Activity ◽  
Activated Sludge ◽  
Hydrolytic Enzymes ◽  
Aluminium Oxide ◽  
Cellular Respiration ◽  
Oxide Nanoparticles ◽  
Oxide Compound ◽  
Commercial Use ◽  
Aluminium Oxide Nanoparticles ◽  
Stimulation Of

The increased production and commercial use of nanoparticles (NPs), combined with a lack of regulation regarding their disposal, may result in the unwanted introduction of NPs to wastewater. Wastewater nutrient removal depends on the metabolisms of activated sludge bacteria and their related key enzymes. Therefore, the aim of this work was to determine the effect of aluminium oxide nanoparticles concentrations on the activated sludge enzymatic activity of microorganisms. Tested nanoparticles inhibition cellular respiration in TTC method in the four highest tested concentrations. Moreover, in most samples observed increase dehydrogenase activity. In this study, nano-Al2O3 also caused a clear stimulation of the activity of hydrolytic enzymes microorganisms of activate sludge. Effects of aluminum oxide (compound in bulk forms) on enzymatic activity were different than in the case of the nano from of Al2O3.

scholarly journals Impact of Solvents, Magnesium Oxide and Aluminium Oxide Nanoparticles on the Photophysical Properties of Acridine Orange Dye

2021 ◽  
pp. 1-7
Author(s):  
Fairooz Kareem ◽  
Mahasin Al-Kadhemy ◽  
Asrar Saeed
Keyword(s):  
Acridine Orange ◽  
Magnesium Oxide ◽  
Fluorescence Spectra ◽  
Aluminium Oxide ◽  
Blue Shift ◽  
Red Shift ◽  
Oxide Nanoparticles ◽  
Absorption And Fluorescence Spectra ◽  
Aluminium Oxide Nanoparticles ◽  
Al2o3 Nps

Absorption and fluorescence spectroscopy techniques were applied to investigate the photophysical characteristics of acridine orange (AO) dye in solvents that included distilled water, dimethyl sulfoxide (DMSO), acetone and ethanol in various concentrations (1×10-4–1×10-6) M. All of the samples were served at room temperature. The relationships between various parameters describing the strength of optical transitions in atoms and molecules were reviewed. This study expresses various viewpoints by describing how concentration and solvent affect the dye's absorption and fluorescence spectra. The absorption spectra of AO exhibit a band at (490 nm), except for DMSO, which shifts more towards red by 5 nm. The fluorescence spectra show a blue shift in AO aqueous solution around 6 nm until (0.5×10-4) M, followed by a red shift at around 7 nm at (1×10-6) M. There is a blue shift in (1×10-5) M for DMSO at around 4 nm, then a 10 nm red shift in higher concentrations as well as a 9 nm red shift in acetone and 6 nm in ethanol. Adding magnesium oxide nanoparticles (MgO NPs) quenched AO in both absorption and fluorescence spectra, whereas maximum fluorescence and intensity increased when aluminium oxide nanoparticles (Al2O3 NPs) were added to the solution. KEYWORDS Laser dye, absorption spectrum, fluorescence spectrum, MgO NPs, Al2O3 NPs

Effect of low-dose exposure of aluminium oxide nanoparticles in Swiss albino mice: Histopathological changes and oxidative damage

2020 ◽  
Vol 36 (8) ◽  
pp. 567-579
Author(s):  
Arpita De ◽  
Swarupa Ghosh ◽  
Manoswini Chakrabarti ◽  
Ilika Ghosh ◽  
Ritesh Banerjee ◽  
...  
Keyword(s):  
Dna Damage ◽  
Oxidative Damage ◽  
Redox Homeostasis ◽  
Aluminium Oxide ◽  
Hydrodynamic Diameter ◽  
Oxide Nanoparticles ◽  
Physico Chemical ◽  
Living Organisms ◽  
Aluminium Oxide Nanoparticles

Rapid growth in the use of aluminium oxide nanoparticles (Al2O3 NPs) in various fields such as medicine, pharmacy, cosmetic industries, and engineering creates concerns since the literature is replete with data regarding their toxicity in living organisms. The objective of the present study was to demonstrate the potential toxicological manifestations of repeated exposure to Al2O3 NP at low doses in vivo. In the present study, Al2O3 NP was orally administered at 15, 30 or 60 mg kg−1 body weight for 5 days to Swiss albino male mice. A battery of well-defined assays was undertaken to evaluate aluminium (Al) bioaccumulation, haematological and histological changes, oxidative damage and genotoxicity. Physico-chemical characterisation demonstrated increases in hydrodynamic diameter along the concentration gradient of Al2O3 NP dispersed in MilliQ water. Brain, liver, spleen, kidney and testes showed high Al retention levels. Histopathological lesions were prominent in the brain and liver. Al2O3 NP treatment increased levels of lipid peroxidation and decreased glutathione content in the test organs at all dose levels. The enzyme activities of catalase and superoxide dismutase were also significantly altered. DNA damage quantified using the comet assay was markedly increased in all the soft organs studied. Anatomical abnormalities, redox imbalance and DNA damage were positively correlated with Al retention in the respective organs. Size, zeta potential and colloidal state might have contributed to the bio-physico-chemical interactions of the NPs in vivo and were responsible for the non-linear dose response. The overall data indicate that Al2O3 NP exposure may result in adverse health consequences, inclusive of but not limited to disturbed redox homeostasis, hepatocellular toxicity, neurodegeneration and DNA damage.

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