Cytotoxic, genotoxic and the hemolytic effect of titanium dioxide (TiO2) nanoparticles on human erythrocyte and lymphocyte cellsin vitro

2013 ◽  
Vol 33 (10) ◽  
pp. 1097-1110 ◽  
Author(s):  
Manosij Ghosh ◽  
Anirban Chakraborty ◽  
Anita Mukherjee
Keyword(s):  
Titanium Dioxide ◽  
Tio2 Nanoparticles ◽  
Human Erythrocyte ◽  
Hemolytic Effect

scholarly journals Responses of metabolic enzymes (GOT, GPT and LDH) in an Indian major carp Cirrhinus mrigala exposed to titanium dioxide (TiO2 ) nanorods under short-term exposure

2020 ◽  
Vol 15 ◽  
pp. 69-78
Author(s):  
B. Rangasamy ◽  
A.P. Ashokan ◽  
M. Ramesh ◽  
A. Narayanasamy
Keyword(s):  
Titanium Dioxide ◽  
Tio2 Nanoparticles ◽  
Aquatic Organisms ◽  
Tio2 Nanorods ◽  
Freshwater Ecosystem ◽  
X Ray Diffraction ◽  
Short Term ◽  
Indian Major Carp ◽  
Cirrhinus Mrigala ◽  
Short Term Exposure

Titanium dioxide (TiO2) nanoparticles are extensively manufactured due to their potential properties and applications invarious fields such as biomedical, electrical and environmental. These particles are likely to reach the aquatic environmentand may cause adverse effects on aquatic organisms. In this study, we investigated the effects of different concentrations (1, 50 and 100 mg L-l) of TiO2 nanorods (NRs). The enzymatic activity of glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT), and lactate dehydrogenase (LDH) was measured in the liver and muscle of an Indian major carp, Cirrhinus mrigala, under short-term exposure (96 h). The synthesised particles were characterized using X-ray diffraction (XRD), scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), UV-Visspectroscopy (UV-Vis) and photoluminescence (PL) techniques before conducting the toxicity assay. The GOT and GPT activities were significantly elevated in both liver and muscle of fish treated with TiO2 nanorods (except 50 mg L-l in muscle for GPT). Similarly, the activity of LDH was also found to be elevated. The findings of the present investigation suggest that TiO2:NRs might have be absorbed, circulated, accumulated in liver and muscles of C. mrigala resulting in alterations in the enzyme activities. The results revealed that TiO2 nanorods induced alterations in GOT, GPT and LDH activities of fish at tested concentrations. The alterations of these enzymatic parameters can be useful for monitoring the environmental contamination of titanium dioxide (TiO2) nanoparticles in freshwater ecosystem.

scholarly journals Study on penetration of titanium dioxide (TiO2) nanoparticles into intact and damaged skin in vitro

2010 ◽  
Vol 35 (1) ◽  
pp. 107-113 ◽  
Author(s):  
Mika Senzui ◽  
Toshiaki Tamura ◽  
Keiko Miura ◽  
Yoshiaki Ikarashi ◽  
Yoshiteru Watanabe ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Tio2 Nanoparticles

Genotoxicity of titanium dioxide (TiO2) nanoparticles at two trophic levels: Plant and human lymphocytes

Chemosphere ◽  
2010 ◽  
Vol 81 (10) ◽  
pp. 1253-1262 ◽  
Author(s):  
Manosij Ghosh ◽  
Maumita Bandyopadhyay ◽  
Anita Mukherjee
Keyword(s):  
Titanium Dioxide ◽  
Tio2 Nanoparticles ◽  
Human Lymphocytes ◽  
Trophic Levels

Environmental assessment of a bottom-up hydrolytic synthesis of TiO2 nanoparticles

2015 ◽  
Vol 17 (1) ◽  
pp. 518-531 ◽  
Author(s):  
Martina Pini ◽  
Roberto Rosa ◽  
Paolo Neri ◽  
Federica Bondioli ◽  
Anna Maria Ferrari
Keyword(s):  
Titanium Dioxide ◽  
Tio2 Nanoparticles ◽  
Environmental Assessment ◽  
Sol Gel ◽  
Lca Methodology ◽  
Bottom Up ◽  
Sol Gel Synthesis

A green metrics evaluation of the bottom-up hydrolytic sol–gel synthesis of titanium dioxide (TiO2) nanoparticles has been performed by following two different approaches, namely, EATOS software and LCA methodology.

Subacute toxicity of titanium dioxide (TiO2) nanoparticles in male rats: emotional behavior and pathophysiological examination

2015 ◽  
Vol 22 (11) ◽  
pp. 8728-8737 ◽  
Author(s):  
Naima Rihane Ben Younes ◽  
Salem Amara ◽  
Imen Mrad ◽  
Imen Ben-Slama ◽  
Mustapha Jeljeli ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Tio2 Nanoparticles ◽  
Emotional Behavior ◽  
Male Rats ◽  
Subacute Toxicity

scholarly journals Structural Analysis of Plants Exposed to Titanium Dioxide (TiO2) Nanoparticles

2013 ◽  
Vol 19 (S2) ◽  
pp. 104-105 ◽  
Author(s):  
E. McDaniel ◽  
I. Chen ◽  
E. Balogh ◽  
Y. Yang ◽  
S. Ghoshroy
Keyword(s):  
Titanium Dioxide ◽  
Structural Analysis ◽  
Tio2 Nanoparticles

Extended abstract of a paper presented at Microscopy and Microanalysis 2013 in Indianapolis, Indiana, USA, August 4 – August 8, 2013.

Dispersion and stability of titanium dioxide nanoparticles in aqueous suspension: effects of ultrasonication and concentration

2013 ◽  
Vol 67 (1) ◽  
pp. 147-151 ◽  
Author(s):  
J. Qi ◽  
Y. Y. Ye ◽  
J. J. Wu ◽  
H. T. Wang ◽  
F. T. Li
Keyword(s):  
Titanium Dioxide ◽  
Zeta Potential ◽  
Tio2 Nanoparticles ◽  
Titanium Dioxide Nanoparticles ◽  
Aqueous Suspension ◽  
Solution Chemistry ◽  
Hydrodynamic Diameter ◽  
Nanoparticles Dispersion ◽  
Nanoparticles Concentration ◽  
Nanoparticles Suspension

The increasing applications of titanium dioxide (TiO2) nanoparticles raise concerns about their potential environmental impacts. To investigate the fate and transport of TiO2 nanoparticles in aqueous suspension, ultrasonication is widely used for the dispersion of TiO2 nanoparticles in laboratory-scale studies. There is a pressing need for detailed information on the dispersion and stability of TiO2 nanoparticles. This study investigated the change of size, zeta potential, and pH of TiO2 nanoparticles aqueous suspension under different conditions of ultrasonication and concentrations. It was found that the hydrodynamic diameter of TiO2 nanoparticles decreased with increasing suspension concentration and remained stable for more than 1 hour after sonication, which is enough for experimental research. The pH decreased with increasing nanoparticles concentration. Ultrasonication remarkably improved zeta potential to be above 15 mV for all the samples. Therefore, 20 minutes of ultrasonication (180 W) is sufficient for the dispersion of this rutile TiO2 nanoparticles suspension, which can remain stable for more than 1 hour. However, the optimum sonication time for TiO2 nanoparticles dispersion is influenced by many factors, such as TiO2 nanoparticles concentration, solution chemistry, and sonicator parameters.

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