Effects of embryonic exposure to polychlorinated biphenyls on zebrafish (Danio rerio) retinal development

2011 ◽  
Vol 32 (3) ◽  
pp. 186-193 ◽  
Author(s):  
Yan-Ping Wang ◽  
Qin Hong ◽  
Da-ni Qin ◽  
Chun-Zhao Kou ◽  
Chun-Mei Zhang ◽  
...  
2021 ◽  
Vol 228 ◽  
pp. 113007
Author(s):  
Peng Xiao ◽  
Wenhua Li ◽  
Jinfang Lu ◽  
Yang Liu ◽  
Qiulan Luo ◽  
...  

2007 ◽  
Vol 23 (9) ◽  
pp. 529-536 ◽  
Author(s):  
T Şişman ◽  
F Geyikoğlu ◽  
M Atamanalp

Polychlorinated biphenyls are a widespread aquatic contaminant. In this article, specific polychlorinated biphenyl congeners were examined for embryo and early life-stage toxicity in zebrafish ( Danio rerio). A set of three polychlorinated biphenyl congeners (non-ortho polychlorinated biphenyl 126, mono-ortho polychlorinated biphenyl 28 and di-ortho polychlorinated biphenyl 153) were tested. The typical lesions observed were yolk sac edema, vertebra defect, craniofacial malformations (double head, triple retina), anaxial body and inhibition of swim bladder inflation. Moreover, embryo and larval mortality increased and hatching success decreased. The severity of abnormalities and mortalities were concentration- and congener-dependent. Of the compounds tested, polychlorinated biphenyl congener 126 was found to be highly toxic to the fish embryos following exposure. The Lethal Concentration 50 values for polychlorinated biphenyl 28, polychlorinated biphenyl 126, polychlorinated biphenyl 153 calculated by probit analysis were 3.270, 1.298 and 5.375 ppm, respectively. The inhibition of swim bladder inflation was the most sensitive endpoint measured, and it is suggested that the inhibition of swim bladder inflation may be mediated by mechanism with an aryl hydrocarbon receptor activation.


2018 ◽  
Vol 110 (11) ◽  
pp. 933-948 ◽  
Author(s):  
Sarah E. Brown ◽  
Karilyn E. Sant ◽  
Shana M. Fleischman ◽  
Olivia Venezia ◽  
Monika A. Roy ◽  
...  

2020 ◽  
Vol 22 (3) ◽  
pp. 728-739 ◽  
Author(s):  
Katharine A. Horzmann ◽  
Ana M. Portales ◽  
Kathryn G. Batcho ◽  
Jennifer L. Freeman

Embryonic exposure to ecologically relevant concentrations of TCE disrupts development, morphology, heart rate, and behavior in the zebrafish (Danio rerio) model system.


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